| Non-canonical function of ADAM10 in presynaptic plasticity. | Non-canonical function of ADAM10 in presynaptic plasticity.
Bär J, Fanutza T, Reimann CC, Seipold L, Grohe M, Bolter JR, Delfs F, Bucher M, Gee CE, Schweizer M, Saftig P, Mikhaylova M., Free PMC Article | 08/21/2024 |
| Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation. | Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation.
Babendreyer A, Kieselhorst J, Rinkens C, Lyashenko AM, Düsterhöft S, Jahr H, Craveiro RB, Wolf M, Ludwig A., Free PMC Article | 06/25/2024 |
| A Disintegrin And Metalloprotease 10 expression within the murine central nervous system. | A Disintegrin And Metalloprotease 10 expression within the murine central nervous system.
Padilla-Ferrer A, Carrete A, Simon A, Meffre D, Jafarian-Tehrani M. | 06/5/2024 |
| SHMT2 Mediates Small-Molecule-Induced Alleviation of Alzheimer Pathology Via the 5'UTR-dependent ADAM10 Translation Initiation. | SHMT2 Mediates Small-Molecule-Induced Alleviation of Alzheimer Pathology Via the 5'UTR-dependent ADAM10 Translation Initiation.
Song L, Pan QL, Zhou GF, Liu SW, Zhu BL, Lin PJ, Hu XT, Zha JS, Long Y, Luo B, Chen J, Tang Y, Tang J, Xiang XJ, Xie XY, Deng XJ, Chen GJ., Free PMC Article | 03/21/2024 |
| ADAM10 and Neprilysin level decreases in immune cells of mice bearing metastatic breast carcinoma: Possible role in cancer inflammatory response. | ADAM10 and Neprilysin level decreases in immune cells of mice bearing metastatic breast carcinoma: Possible role in cancer inflammatory response.
Erin N, Akdeniz Ö. | 01/29/2024 |
| Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis. | Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis.
Alfano DN, Miller MJ, Bubeck Wardenburg J., Free PMC Article | 12/5/2023 |
| Treadmill workout activates PPARalpha in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease. | Treadmill workout activates PPARα in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease.
Rangasamy SB, Jana M, Dasarathi S, Kundu M, Pahan K., Free PMC Article | 03/16/2023 |
| A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain. | A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain.
Guo D, Huang F, Xue R, Ma Y, Xiao L, Lou H, Pan S., Free PMC Article | 02/15/2023 |
| Loss of Adam10 Disrupts Ion Transport in Immortalized Kidney Collecting Duct Cells. | Loss of Adam10 Disrupts Ion Transport in Immortalized Kidney Collecting Duct Cells.
Assmus A, Mullins L, Ward M, Dobie R, Hunter R, Henderson NC, Mullins JJ., Free PMC Article | 02/9/2023 |
| ADAM10- and gamma-secretase-dependent cleavage of the transmembrane protein PTPRT attenuates neurodegeneration in the mouse model of Alzheimer's disease. | ADAM10- and γ-secretase-dependent cleavage of the transmembrane protein PTPRT attenuates neurodegeneration in the mouse model of Alzheimer's disease.
Liu S, Zhang Z, Li L, Yao L, Ma Z, Li J. | 01/11/2023 |
| Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. | Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A., Free PMC Article | 12/31/2022 |
| Metalloprotease ADAM10 inhibition mitigates acute liver injury via repression of intrahepatic inflammation. | Metalloprotease ADAM10 inhibition mitigates acute liver injury via repression of intrahepatic inflammation.
Cheng W, Meng W, Gu Y. | 07/23/2022 |
| The development of ADAM10 endocytosis inhibitors for the treatment of Alzheimer's disease. | The development of ADAM10 endocytosis inhibitors for the treatment of Alzheimer's disease.
Musardo S, Therin S, Pelucchi S, D'Andrea L, Stringhi R, Ribeiro A, Manca A, Balducci C, Pagano J, Sala C, Verpelli C, Grieco V, Edefonti V, Forloni G, Gardoni F, Meli G, Di Marino D, Di Luca M, Marcello E., Free PMC Article | 07/16/2022 |
| The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo. | The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo.
Kirschke S, Ogunsulire I, Selvakumar B, Schumacher N, Sezin T, Rose-John S, Scheffold A, Garbers C, Lokau J., Free PMC Article | 07/2/2022 |
| ADAM10-cleaved ephrin-A5 contributes to prostate cancer metastasis. | ADAM10-cleaved ephrin-A5 contributes to prostate cancer metastasis.
Cai C, Zhang M, Liu L, Zhang H, Guo Y, Lan T, Xu Y, Ma P, Li S., Free PMC Article | 05/28/2022 |
| shRNAs targeting mouse Adam10 diminish cell response to proinflammatory stimuli independently of Adam10 silencing. | shRNAs targeting mouse Adam10 diminish cell response to proinflammatory stimuli independently of Adam10 silencing.
Czarnek M, Stalińska K, Sarad K, Bereta J., Free PMC Article | 05/14/2022 |
| ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease. | ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.
Cozzolino F, Vezzoli E, Cheroni C, Besusso D, Conforti P, Valenza M, Iacobucci I, Monaco V, Birolini G, Bombaci M, Falqui A, Saftig P, Rossi RL, Monti M, Cattaneo E, Zuccato C. | 04/2/2022 |
| Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner. | Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner.
Cheng XS, Shi FX, Zhao KP, Lin W, Li XY, Zhang J, Bu YY, Zhu R, Li XH, Duan DX, Ji XY, Wei JS, Wang JZ, Du J, Zhou XW., Free PMC Article | 01/29/2022 |
| Simvastatin mitigates streptozotocin-induced type 1 diabetes in mice through downregulation of ADAM10 and ADAM17. | Simvastatin mitigates streptozotocin-induced type 1 diabetes in mice through downregulation of ADAM10 and ADAM17.
Abdel-Bakky MS, Alqasoumi A, Altowayan WM, Amin E, Darwish MA. | 01/15/2022 |
| Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone. | Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone.
Diener N, Fontaine JF, Klein M, Hieronymus T, Wanke F, Kurschus FC, Ludwig A, Ware C, Saftig P, Bopp T, Clausen BE, Backer RA., Free PMC Article | 01/15/2022 |
| miR-520d suppresses rapid pacing-induced apoptosis of atrial myocytes through mediation of ADAM10. | miR-520d suppresses rapid pacing-induced apoptosis of atrial myocytes through mediation of ADAM10.
Fu Q, Tang Y, Peng J, He J, Zou Q, Yan S, Zheng Z, Pan H. | 12/18/2021 |
| ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis. | ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis.
Zbodakova O, Chalupsky K, Sarnova L, Kasparek P, Jirouskova M, Gregor M, Sedlacek R., Free PMC Article | 11/13/2021 |
| ADAM10 partially protects mice against influenza pneumonia by suppressing specific myeloid cell population. | ADAM10 partially protects mice against influenza pneumonia by suppressing specific myeloid cell population.
Okamori S, Ishii M, Asakura T, Suzuki S, Namkoong H, Kagawa S, Hegab AE, Yagi K, Kamata H, Kusumoto T, Ogawa T, Takahashi H, Yoda M, Horiuchi K, Hasegawa N, Fukunaga K. | 11/13/2021 |
| ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage. | ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage.
Sachs M, Wetzel S, Reichelt J, Sachs W, Schebsdat L, Zielinski S, Seipold L, Heintz L, Müller SA, Kretz O, Lindenmeyer M, Wiech T, Huber TB, Lüllmann-Rauch R, Lichtenthaler SF, Saftig P, Meyer-Schwesinger C., Free PMC Article | 10/9/2021 |
| Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site. | Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site.
Sriranganathan S, Tutunea-Fatan E, Abbasi A, Gunaratnam L. | 07/17/2021 |