| Network analysis of DUSP12 partners in the nucleus under genotoxic stress. | Network analysis of DUSP12 partners in the nucleus under genotoxic stress.
Monteiro LF, Forti FL. | 07/18/2020 |
| Results from a study on gene variability markers in early-stage human embryos shows that DUSP12 is a putative variability marker for the 3-day, 8-cell embryo stage. | Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.
Hasegawa Y, Taylor D, Ovchinnikov DA, Wolvetang EJ, de Torrenté L, Mar JC., Free PMC Article | 07/23/2018 |
| A significant decrease in DUSP12 expression in hypertrophic hearts and cardiomyocytes. | Dual specific phosphatase 12 ameliorates cardiac hypertrophy in response to pressure overload.
Li WM, Zhao YF, Zhu GF, Peng WH, Zhu MY, Yu XJ, Chen W, Xu DC, Xu YW. | 07/8/2017 |
| These results propagate a role for dual specificity phosphatases at RNP particles and suggest that hYVH1 may affect a variety of fundamental cellular processes by regulating messenger ribonucleoprotein (mRNP) dynamics. | The Atypical Dual Specificity Phosphatase hYVH1 Associates with Multiple Ribonucleoprotein Particles.
Geng Q, Xhabija B, Knuckle C, Bonham CA, Vacratsis PO., Free PMC Article | 06/3/2017 |
| hYVH1 is a novel modulator of cell cycle progression mediated by a phosphorylation site located at the C-terminal end of the zinc-binding domain | The dual-specificity phosphatase hYVH1 (DUSP12) is a novel modulator of cellular DNA content.
Kozarova A, Hudson JW, Vacratsis PO. | 10/1/2011 |
| propose that the BRC repeats in BRCA2 cooperate in a partially redundant but reinforcing manner to ensure a high probability of RAD51 filament formation | Characterization of a human cell line stably over-expressing the candidate oncogene, dual specificity phosphatase 12.
Cain EL, Braun SE, Beeser A., Free PMC Article | 09/24/2011 |
| these data suggests common SNPs within DUSP12-ATF6 locus may not play a major role in glucose metabolism in the Chinese. | Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese population.
Hu C, Zhang R, Wang C, Ma X, Wang J, Bao Y, Xiang K, Jia W., Free PMC Article | 02/26/2011 |
| tudies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML. | Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.
Biernacki MA, Marina O, Zhang W, Liu F, Bruns I, Cai A, Neuberg D, Canning CM, Alyea EP, Soiffer RJ, Brusic V, Ritz J, Wu CJ., Free PMC Article | 03/15/2010 |
| Data determined that hYVH1 forms intramolecular disulfide bonds at the catalytic cleft as well as within the zinc binding domain to avoid irreversible inactivation during severe oxidative stress. | Redox regulation of the human dual specificity phosphatase YVH1 through disulfide bond formation.
Bonham CA, Vacratsis PO., Free PMC Article | 01/21/2010 |
| hYVH1 is a novel cell survival phosphatase that co-operates with Hsp70 to positively affect cell viability in response to cellular insults. | The dual-specificity phosphatase hYVH1 interacts with Hsp70 and prevents heat-shock-induced cell death.
Sharda PR, Bonham CA, Mucaki EJ, Butt Z, Vacratsis PO. | 01/21/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Type 2 diabetes susceptibility genes on chromosome 1q21-24.
Hasstedt SJ, Chu WS, Das SK, Wang H, Elbein SC. | 04/3/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articles[Association of -6735T-->C variant of glucokinase-associated dual-specificity phosphatase 12 gene with type 2 diabetes in Chinese].
Gao F, Zhang R, Hu C, Fang QC, Wang CR, Ma XJ, Lu JX, Xu J, Jia WP, Xiang KS. Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes.
Das SK, Chu WS, Hale TC, Wang X, Craig RL, Wang H, Shuldiner AR, Froguel P, Deloukas P, McCarthy MI, Zeggini E, Hasstedt SJ, Elbein SC, Das SK, Chu WS, Hale TC, Wang X, Craig RL, Wang H, Shuldiner AR, Froguel P, Deloukas P, McCarthy MI, Zeggini E, Hasstedt SJ, Elbein SC. | 03/13/2008 |
| Our data suggest that sequences in or upstream of DUSP12 may contribute to type 2 diabetes susceptibility, but the lack of replication suggests a small effect size. | Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes.
Das SK, Chu WS, Hale TC, Wang X, Craig RL, Wang H, Shuldiner AR, Froguel P, Deloukas P, McCarthy MI, Zeggini E, Hasstedt SJ, Elbein SC, Das SK, Chu WS, Hale TC, Wang X, Craig RL, Wang H, Shuldiner AR, Froguel P, Deloukas P, McCarthy MI, Zeggini E, Hasstedt SJ, Elbein SC. | 01/21/2010 |