| Differential Glial Chitotriosidase 1 and Chitinase 3-like Protein 1 Expression in the Human Primary Visual Cortex and Cerebellum after Global Hypoxia-Ischemia. | Differential Glial Chitotriosidase 1 and Chitinase 3-like Protein 1 Expression in the Human Primary Visual Cortex and Cerebellum after Global Hypoxia-Ischemia.
Yilmazer-Hanke D, Ouali Alami N, Fang L, Klotz S, Kovacs GG, Pankratz H, Weis J, Katona I, Scheuerle A, Streit WJ, Del Tredici K. | 12/17/2022 |
| Longitudinal and Comparative Measures of Serum Chitotriosidase and YKL-40 in Patients With Idiopathic Pulmonary Fibrosis. | Longitudinal and Comparative Measures of Serum Chitotriosidase and YKL-40 in Patients With Idiopathic Pulmonary Fibrosis.
Majewski S, Szewczyk K, Jerczyńska H, Miłkowska-Dymanowska J, Białas AJ, Gwadera Ł, Piotrowski WJ., Free PMC Article | 04/16/2022 |
| Increased Plasma YKL-40 Level and Chitotriosidase Activity in Cystic Fibrosis Patients. | Increased Plasma YKL-40 Level and Chitotriosidase Activity in Cystic Fibrosis Patients.
Topcu DB, Tugcu G, Er B, Polat SE, Hizal M, Yalcin EE, Ersoz DD, Coplu L, Ozcelik U, Kiper N, Lay I, Oztas Y. | 04/9/2022 |
| Cardiopharyngeal deconstruction and ancestral tunicate sessility. | Cardiopharyngeal deconstruction and ancestral tunicate sessility.
Ferrández-Roldán A, Fabregà-Torrus M, Sánchez-Serna G, Duran-Bello E, Joaquín-Lluís M, Bujosa P, Plana-Carmona M, Garcia-Fernàndez J, Albalat R, Cañestro C. | 04/2/2022 |
| Serum chitotriosidase and YKL-40 in acute pancreatitis: Reliability as prognostic marker for disease severity and correlation with inflammatory markers | Serum chitotriosidase and YKL-40 in acute pancreatitis: Reliability as prognostic marker for disease severity and correlation with inflammatory markers.
Ünal Çetin E, Kamiş F, Çetin AU, Beyazit Y, Kekilli M., Free PMC Article | 01/8/2022 |
| A novel marker of systemic inflammation in psoriasis and related comorbidities: chitotriosidase | A novel marker of systemic inflammation in psoriasis and related comorbidities: chitotriosidase.
İlanbey B, Elmas ÖF, Sözmen EY, Günay Ü, Demirbaş A, Atasoy M, Türsen Ü, Lotti T. | 12/4/2021 |
| Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy. | Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy.
Freigang M, Steinacker P, Wurster CD, Schreiber-Katz O, Osmanovic A, Petri S, Koch JC, Rostásy K, Falkenburger B, Ludolph AC, Otto M, Hermann A, Günther R., Free PMC Article | 09/18/2021 |
| Chitotriosidase as biomarker for early stage amyotrophic lateral sclerosis: a multicenter study. | Chitotriosidase as biomarker for early stage amyotrophic lateral sclerosis: a multicenter study.
Steinacker P, Feneberg E, Halbgebauer S, Witzel S, Verde F, Oeckl P, Van Damme P, Gaur N, Gray E, Grosskreutz J, Jardel CG, Kachanov M, Kuhle J, Lamari F, Maceski A, Del Mar Amador M, Mayer B, Morelli C, Petri S, Poesen K, Raaphorst J, Salachas F, Silani V, Turner MR, Verbeek MM, Volk AE, Weishaupt JH, Weydt P, Ludolph AC, Otto M. | 09/11/2021 |
| Chitotriosidase gene polymorphisms and mutations limit the determination of chitotriosidase expression in sarcoidosis. | Chitotriosidase gene polymorphisms and mutations limit the determination of chitotriosidase expression in sarcoidosis.
Csongrádi A, Altorjay IT, Fülöp GÁ, Enyedi A, Enyedi EE, Hajnal P, Takács I, Tóth A, Papp Z, Fagyas M. | 08/21/2021 |
| Association of plasma YKL-40 with brain amyloid-beta levels, memory performance, and sex in subjective memory complainers. | Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers.
Vergallo A, Lista S, Lemercier P, Chiesa PA, Zetterberg H, Blennow K, Potier MC, Habert MO, Baldacci F, Cavedo E, Caraci F, Dubois B, Hampel H, INSIGHT-preAD study group and the Alzheimer Precision Medicine Initiative (APMI), INSIGHT-preAD study group, Alzheimer Precision Medicine Initiative (APMI). | 07/24/2021 |
| Investigation of seminal plasma chitotriosidase-1 and leukocyte elastase as potential markers for 'silent' inflammation of the reproductive tract of the infertile male - a pilot study. | Investigation of seminal plasma chitotriosidase-1 and leukocyte elastase as potential markers for 'silent' inflammation of the reproductive tract of the infertile male - a pilot study.
Kratz EM, Zurawska-Plaksej E, Solkiewicz K, Kokot I, Faundez R, Piwowar A. | 07/17/2021 |
| Chitotriosidase, a biomarker of amyotrophic lateral sclerosis, accentuates neurodegeneration in spinal motor neurons through neuroinflammation. | Chitotriosidase, a biomarker of amyotrophic lateral sclerosis, accentuates neurodegeneration in spinal motor neurons through neuroinflammation.
Varghese AM, Ghosh M, Bhagat SK, Vijayalakshmi K, Preethish-Kumar V, Vengalil S, Chevula PC, Nashi S, Polavarapu K, Sharma M, Dhaliwal RS, Philip M, Nalini A, Alladi PA, Sathyaprabha TN, Raju TR., Free PMC Article | 07/3/2021 |
| Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity. | Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity.
Kimura M, Watanabe T, Sekine K, Ishizuka H, Ikejiri A, Sakaguchi M, Kamaya M, Yamanaka D, Matoska V, Bauer PO, Oyama F. | 04/17/2021 |
| Dramatically changed immune-related molecules as early diagnostic biomarkers of non-small cell lung cancer. | Dramatically changed immune-related molecules as early diagnostic biomarkers of non-small cell lung cancer.
Ye X, Zhang N, Jin Y, Xu B, Guo C, Wang X, Su Y, Yang Q, Song J, Yu W, Cheng P, Cheng L, Gong Y, Fu X, Sun H. | 10/24/2020 |
| Clinical Significance of Serum Chitotriosidase Level in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease. | Clinical Significance of Serum Chitotriosidase Level in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease.
Fujisawa T, Hozumi H, Yasui H, Suzuki Y, Karayama M, Furuhashi K, Enomoto N, Nakamura Y, Inui N, Suda T. | 09/19/2020 |
| Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes. | Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes.
Vu L, An J, Kovalik T, Gendron T, Petrucelli L, Bowser R., Free PMC Article | 08/22/2020 |
| angiotensin converting enzyme and chitotriosidase analysis improves the laboratory diagnosis of sarcoidosis | Combined application of angiotensin converting enzyme and chitotriosidase analysis improves the laboratory diagnosis of sarcoidosis.
Enyedi A, Csongrádi A, Altorjay IT, Beke GL, Váradi C, Enyedi EE, Kiss DR, Bányai E, Kalina E, Kappelmayer J, Tóth A, Papp Z, Takács I, Fagyas M. | 06/6/2020 |
| Determined chitotriosidase-1 (CHIT1) levels in adipose tissue and plasma of individuals ranging from lean to obese, as well as in patients with type 2 diabetes. Found plasma levels of CHIT1 is of limited value as a circulating biomarker for adipose tissue inflammation in human subjects. | Evaluation of chitotriosidase as a biomarker for adipose tissue inflammation in overweight individuals and type 2 diabetic patients.
Tans R, van Diepen JA, Bijlsma S, Verschuren L, Suppers A, Stienstra R, Wevers RA, Tack CJ, Gloerich J, van Gool AJ. | 05/30/2020 |
| These studies demonstrate that CHIT1 regulates TGF-beta1/SMAD7 axis via TGFBRAP1 and FOXO3 and highlight the importance of these pathways in the pathogenesis of pulmonary fibrosis. | Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.
Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG., Free PMC Article | 01/25/2020 |
| The median CHIT1 concentration in CSF was fourfold to ninefold increased in the patients with genetic ALS compared with controls, asymptomatic mutation carriers and genetic frontotemporal dementia cases. | Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase.
Oeckl P, Weydt P, Steinacker P, Anderl-Straub S, Nordin F, Volk AE, Diehl-Schmid J, Andersen PM, Kornhuber J, Danek A, Fassbender K, Fliessbach K, German Consortium for Frontotemporal Lobar Degeneration, Jahn H, Lauer M, Müller K, Knehr A, Prudlo J, Schneider A, Thal DR, Yilmazer-Hanke D, Weishaupt JH, Ludolph AC, Otto M. | 12/14/2019 |
| The elevated CHIT1 and CYP1B1 are early indicators of chronic obstructive pulmonary disease (COPD) development in HIV-infected smokers that may serve as biomarkers for determining this risk. | Upregulation of Chitinase 1 in Alveolar Macrophages of HIV-Infected Smokers.
Logue EC, Neff CP, Mack DG, Martin AK, Fiorillo S, Lavelle J, Vandivier RW, Campbell TB, Palmer BE, Fontenot AP., Free PMC Article | 11/16/2019 |
| In ALS, CHIT1 CSF levels were higher compared with health controls, ALS mimics, and Alzheimer's disease, Parkinson's disease, and frontotemporal lobar degeneration. In the spinal cord of patients with ALS, but not CHIT1 was expressed in the corticospinal tract and CHIT1 staining colocalised with markers of microglia (IBA1) and macrophages (CD68). | Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.
Steinacker P, Verde F, Fang L, Feneberg E, Oeckl P, Roeber S, Anderl-Straub S, Danek A, Diehl-Schmid J, Fassbender K, Fliessbach K, Foerstl H, Giese A, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer GB, Lauer M, Pinkhardt EH, Prudlo J, Rosenbohm A, Schneider A, Schroeter ML, Tumani H, von Arnim CAF, Weishaupt J, Weydt P, Ludolph AC, Yilmazer Hanke D, Otto M, FTLDc study group. | 07/6/2019 |
| pretreatment ChT levels appear to be mainly dependent on the presence/absence of the dup24 allele | Chitotriosidase on treatment-naïve patients with Gaucher disease: A genotype vs phenotype study.
Sperb-Ludwig F, Heineck BL, Michelin-Tirelli K, Alegra T, Schwartz IVD. | 03/23/2019 |
| CHIT1 might be considered as a circulating biomarker in polycythemia vera. Additional studies are needed to clarify the role of CHIT1 in promoting disease progression and bone marrow fibrosis in polycythemia vera. | Serum chitotriosidase: a circulating biomarker in polycythemia vera.
Krecak I, Gveric-Krecak V, Roncevic P, Basic-Kinda S, Gulin J, Lapic I, Fumic K, Ilic I, Horvat I, Zadro R, Holik H, Coha B, Peran N, Aurer I, Durakovic N. | 11/3/2018 |
| Data suggest that up-regulation of amniotic fluid chitotriosidase may serve as prenatal diagnostic biomarker for lysosomal storage disorders, more specifically for Gaucher and Niemann-Pick A/B diseases; these findings appear to result from gene duplication. This study was conducted in India. | Utility of amniotic fluid chitotriosidase in the prenatal diagnosis of lysosomal storage disorders.
Kadali S, Madalasa T, Reddy GM, Naushad SM. | 10/27/2018 |