Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration. | Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration. Ding JY, Yan X, Zhang RJ, Zhang HQ, Kang L, Jia CY, Thorne RF, Liu XY, Shen CL., Free PMC Article | 04/5/2024 |
The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study. | The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study. Iwanicka J, Balcerzyk-Matić A, Iwanicki T, Mizia-Stec K, Bańka P, Filipecki A, Gawron K, Jarosz A, Nowak T, Krauze J, Niemiec P., Free PMC Article | 02/28/2024 |
ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1. | ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1. Sharifi MA, Wierer M, Dang TA, Milic J, Moggio A, Sachs N, von Scheidt M, Hinterdobler J, Müller P, Werner J, Stiller B, Aherrahrou Z, Erdmann J, Zaliani A, Graettinger M, Reinshagen J, Gul S, Gribbon P, Maegdefessel L, Bernhagen J, Sager HB, Mann M, Schunkert H, Kessler T., Free PMC Article | 10/2/2023 |
miR-654-5p Suppresses Migration and Proliferation of Vascular Smooth Muscle Cells by Targeting ADAMTS-7. | miR-654-5p Suppresses Migration and Proliferation of Vascular Smooth Muscle Cells by Targeting ADAMTS-7. Li L, Wang S, Wang M, Liu G, Yang Z, Wang L. | 07/26/2023 |
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice. | ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice. Gong Z, Huang J, Wang D, Yang S, Ma Z, Fu Y, Ma Q, Kong W. | 03/29/2023 |
Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways. | Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways. Yu Z, Zekavat SM, Haidermota S, Bernardo R, MacDonald BT, Libby P, Finucane HK, Natarajan P., Free PMC Article | 05/7/2022 |
Coronary Disease Association With ADAMTS7 Is Due to Protease Activity. | Coronary Disease Association With ADAMTS7 Is Due to Protease Activity. Mizoguchi T, MacDonald BT, Bhandary B, Popp NR, Laprise D, Arduini A, Lai D, Zhu QM, Xing Y, Kaushik VK, Kathiresan S, Ellinor PT., Free PMC Article | 01/15/2022 |
ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas. | ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas. Wang C, Chen Y, Xiang H, Wu X, Tang Q, Ma X, Zhang L., Free PMC Article | 11/6/2021 |
Hypomethylation of DNA promoter upregulates ADAMTS7 and contributes to HTR-8/SVneo and JEG-3 cells abnormalities in pre-eclampsia. | Hypomethylation of DNA promoter upregulates ADAMTS7 and contributes to HTR-8/SVneo and JEG-3 cells abnormalities in pre-eclampsia. Zhang L, Zhao F, Li C, Li H, Tang Q, Chen Y, Yao Y, Ding Z, Xu Y, Chen A, Liu S. | 04/13/2021 |
Association of polymorphisms in ADAMTS-7 gene with the susceptibility to coronary artery disease - a systematic review and meta-analysis. | Association of polymorphisms in ADAMTS-7 gene with the susceptibility to coronary artery disease - a systematic review and meta-analysis. Hosseini DK, Ataikia S, Hosseini HK, Han B, Sun H., Free PMC Article | 04/3/2021 |
ADATMS-7 regulates the focal adhesion kinase signaling and promotes invasiveness of trophoblasts in early pregnancy. | ADATMS-7 regulates the focal adhesion kinase signaling and promotes invasiveness of trophoblasts in early pregnancy. Meng YH, Zhang JB, Sun YL, Liu XL. | 02/13/2021 |
Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis. | Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis. Pu X, Chan K, Yang W, Xiao Q, Zhang L, Moore AD, Liu C, Webb TR, Caulfield MJ, Samani NJ, Zhu J, Ye S. | 01/16/2021 |
Upregulation of miR423 improves autologous vein graft restenosis via targeting ADAMTS7. | Upregulation of miR‑423 improves autologous vein graft restenosis via targeting ADAMTS‑7. Ren W, Liang L, Li Y, Wei FY, Mu N, Zhang L, He W, Cao Y, Xiong D, Li H., Free PMC Article | 09/12/2020 |
Genetic variants of ADAMTS7 confer risk for ischaemic stroke in the Chinese population. | Genetic variants of ADAMTS7 confer risk for ischaemic stroke in the Chinese population. Chen L, Hu W, Li S, Yao S, Wang M, Chen X, Chen S, Deng F, Zhu P, Li K, Zhong W, Zhao B, Ma G, Li Y., Free PMC Article | 09/5/2020 |
Data show that common variants in A disintegrin and metalloproteinase with thrombospondin motifs 7 protein (ADAMTS7) and zinc finger, C3HC-type containing 1 protein (ZC3HC1) genes contribute to an increased risk for both coronary artery disease (CAD) and large artery ischemic stroke (LA atherosclerotic) IS. | ADAMTS7 and ZC3HC1 Share Genetic Predisposition to Coronary Artery Disease and Large Artery Ischemic Stroke. Jafaripour S, Sasanejad P, Dadgarmoghaddam M, Sadr-Nabavi A. | 08/12/2020 |
ADAMTS7 tagSNP rs3825807 contributes to MI susceptibility in the Chinese Han population. | Association between ADAMTS7 TagSNPs and the risk of myocardialinfarction. Liang LL, Zhou YL, Cheng J, Xiao YT, Tang ZB, Liu SM, Lian JC, Wang XX, Liu X, Xiong XD. | 05/2/2020 |
findings reveal LTBP4 as an ADAMTS7 substrate, whose cleavage may potentially impact elastogenesis in the cardiovascular system. | Proteomic discovery of substrates of the cardiovascular protease ADAMTS7. Colige A, Monseur C, Crawley JTB, Santamaria S, de Groot R., Free PMC Article | 12/14/2019 |
Degenerated human biceps tendons had reduced ADAMTS7 mRNA compared with healthy biceps tendons, which expressed both ADAMTS7 and ADAMTS12. These results suggest that ADAMTS7 and ADAMTS12 may be essential for human tendon health. | The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification. Mead TJ, McCulloch DR, Ho JC, Du Y, Adams SM, Birk DE, Apte SS., Free PMC Article | 11/30/2019 |
ADAMTS7 polymorphisms of both rs7173743 and rs3825807 were associated with carotid plaque vulnerability but not the prevalence of ischemic stroke. The T/T genotype of rs7173743 and A/A genotype of rs3825807 were considered as risk genotypes for vulnerable plaque susceptibility. In conclusion, ADAMTS7 variants rs3825807 and rs7173743 are associated with the risk for carotid plaque vulnerability. | Association between ADAMTS7 polymorphism and carotid artery plaque vulnerability. Li HW, Shen M, Gao PY, Li ZR, Cao JL, Zhang WL, Sui BB, Wang YX, Wang YJ., Free PMC Article | 11/9/2019 |
Serum ADAMTS7 level is positively associated with acute coronary syndrome, and patients with the CT/TT genotype at the rs1994016 allele are less prone to suffer from ACS. | Association of serum ADAMTS7 levels and genetic variant rs1994016 with acute coronary syndrome in a Chinese population: A case control study. Lin Y, Chen H, Wang Y, Jin C, Lin X, Wang C, Lu Y, Chen Z, Wang JA, Xiang M. | 10/26/2019 |
presents the expression levels of ADAMTS-7 and COMP in the decidual tissues of mice and humans suffering from SA. | Upregulation of ADAMTS‑7 and downregulation of COMP are associated with spontaneous abortion. Mu Y, Zhou DN, Yan NN, Ding JL, Yang J., Free PMC Article | 08/3/2019 |
data show that ADAMTS-7 is associated with a vulnerable plaque phenotype in human carotid lesions. These data support previous observations of a potential proatherogenic role of ADAMTS-7. | ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis. Bengtsson E, Hultman K, Dunér P, Asciutto G, Almgren P, Orho-Melander M, Melander O, Nilsson J, Hultgårdh-Nilsson A, Gonçalves I., Free PMC Article | 12/22/2018 |
Multivariate analysis showed that DeltaADAMTS-7(day 7 minus day 1) was independently associated with left ventricular reverse remodeling | Association of serum ADAMTS-7 levels with left ventricular reverse remodeling after ST-elevation myocardial infarction. Wu W, Li J, Yu C, Gao Y, Fan S, Ye X, Wang Y, Zheng J., Free PMC Article | 09/29/2018 |
Genetic variation at the ADAMTS7 locus is associated with reduced severity of coronary artery disease. | Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease. Chan K, Pu X, Sandesara P, Poston RN, Simpson IA, Quyyumi AA, Ye S, Patel RS., Free PMC Article | 07/21/2018 |
Studied gene expression of genetic variants of ADAMTS7 in atherosclerotic occlusive peripheral arterial disease (PAD). Found mRNA levels of ADAMTS7 to be significantly higher in PAD patients than controls, and that the rs1994016 CC and rs3825807 TT genotypes may upregulate ADAMTS7 mRNA levels and may influence PAD development. | Genetic variants rs1994016 and rs3825807 in ADAMTS7 affect its mRNA expression in atherosclerotic occlusive peripheral arterial disease. Bayoglu B, Arslan C, Tel C, Ulutin T, Dirican A, Deser SB, Cengiz M., Free PMC Article | 05/19/2018 |