| DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/beta-Catenin Signaling Pathway. | DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
Wen R, Zhou L, Jiang S, Fan H, Zheng K, Yu Y, Gao X, Hao L, Lou Z, Yu G, Yang F, Zhang W. | 11/7/2023 |
| Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes. | Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes.
Tan L, Cheng W, Liu F, Wang DO, Wu L, Cao N, Wang J., Free PMC Article | 01/22/2022 |
| The actin depolymerizing factor destrin serves as a negative feedback inhibitor of smooth muscle cell differentiation. | The actin depolymerizing factor destrin serves as a negative feedback inhibitor of smooth muscle cell differentiation.
Liao KA, Rangarajan KV, Bai X, Taylor JM, Mack CP., Free PMC Article | 10/30/2021 |
| ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells. | ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells.
Ullo MF, Logue JS., Free PMC Article | 10/9/2021 |
| Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/beta-Catenin Signaling Pathway. | Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway.
Zhang HJ, Chang WJ, Jia CY, Qiao L, Zhou J, Chen Q, Zheng XW, Zhang JH, Li HC, Yang ZY, Liu ZH, Liu GC, Ji SP, Lu F. | 10/2/2021 |
| analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover | TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover.
Chin SM, Jansen S, Goode BL., Free PMC Article | 09/17/2016 |
| Destrin is upregulated in nerve-invasive pancreatic cancer cells and its expression might be related to perineural invasiveness | The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer.
Klose T, Abiatari I, Samkharadze T, De Oliveira T, Jäger C, Kiladze M, Valkovskaya N, Friess H, Michalski CW, Kleeff J. | 01/12/2013 |
| The ADF/cofilin1-dependent severing of actin filaments exposes and promotes the activation of SPCA1, which pumps Ca(2+) into the lumen of the TGN for the sorting of the class of secretory cargo that binds Ca(2+). | ADF/cofilin regulates secretory cargo sorting at the TGN via the Ca2+ ATPase SPCA1.
von Blume J, Alleaume AM, Cantero-Recasens G, Curwin A, Carreras-Sureda A, Zimmermann T, van Galen J, Wakana Y, Valverde MA, Malhotra V. | 07/16/2011 |
| Changes in the expression of cytoskeletal regulatory proteins such as LIMK and cofilin may play a role in weakening thoracic aortic medial tissue, as a precondition to thoracic aortic dissection. | A study of the expression and interaction of Destrin, cofilin, and LIMK in Debakey I type thoracic aortic dissection tissue.
Tian L, Liao MF, Zhang L, Lu QS, Jing ZP. | 03/12/2011 |
| The results of this study suggested that temporally regulated ADF/cofilin activities function in postsynaptic modifications of receptor number and spine size during synaptic plasticity. | ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity.
Gu J, Lee CW, Fan Y, Komlos D, Tang X, Sun C, Yu K, Hartzell HC, Chen G, Bamburg JR, Zheng JQ., Free PMC Article | 10/23/2010 |
| destrin is a significant regulator of various processes important for invasive phenotype of human colon cancer Isreco1 cells whereas cofilin-1 may be involved in only a subset of them | Differential involvement of destrin and cofilin-1 in the control of invasive properties of Isreco1 human colon cancer cells.
Estornes Y, Gay F, Gevrey JC, Navoizat S, Nejjari M, Scoazec JY, Chayvialle JA, Saurin JC, Abello J. | 01/21/2010 |
| differences in actin binding by human ADF and cofilin | Determining the differences in actin binding by human ADF and cofilin.
Yeoh S, Pope B, Mannherz HG, Weeds A. | 01/21/2010 |
| Important sequence differences between actin-depolymerizing factor/cofilin were correlated with unique structural determinants in the F-actin-binding site to account for differences in biochemical activities of the two proteins. | Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor.
Pope BJ, Zierler-Gould KM, Kühne R, Weeds AG, Ball LJ. | 01/21/2010 |
| downregulated following UV exposure in epidermis | Proteomic profiling identifies an UV-induced activation of cofilin-1 and destrin in human epidermis.
Hensbergen P, Alewijnse A, Kempenaar J, van der Schors RC, Balog CA, Deelder A, Beumer G, Ponec M, Tensen CP. | 01/21/2010 |
| In the absence of any crystal structures of ADF or cofilin in complex with actin, these studies provide further information about the binding sites on F-actin for these important actin regulatory proteins. | Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.
Mannherz HG, Ballweber E, Galla M, Villard S, Granier C, Steegborn C, Schmidtmann A, Jaquet K, Pope B, Weeds AG. | 01/21/2010 |