| RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C. | RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C.
Suo J, Wang Y, Wang L, Qiu B, Wang Z, Yan A, Qiang B, Han W, Peng X., Free PMC Article | 01/9/2024 |
| Overexpression of RAB31 in gastric cancer is associated with released exosomes and increased tumor cell invasion and metastasis. | Overexpression of RAB31 in gastric cancer is associated with released exosomes and increased tumor cell invasion and metastasis.
Wu S, Tang C, Zhang QW, Zhuang Q, Ye X, Xia J, Shi Y, Ning M, Dong ZX, Wan XJ., Free PMC Article | 10/20/2023 |
| lncRNA MAGI2-AS3 suppresses castration-resistant prostate cancer proliferation and migration via the miR-106a-5p/RAB31 axis. | lncRNA MAGI2-AS3 suppresses castration-resistant prostate cancer proliferation and migration via the miR-106a-5p/RAB31 axis.
Yang G, Li T, Liu J, Quan Z, Liu M, Guo Y, Wu Y, Ou L, Wu X, Zheng Y. | 03/27/2023 |
| Rab31 promotes metastasis and cisplatin resistance in stomach adenocarcinoma through Twist1-mediated EMT. | Rab31 promotes metastasis and cisplatin resistance in stomach adenocarcinoma through Twist1-mediated EMT.
Chen K, Xu J, Tong YL, Yan JF, Pan Y, Wang WJ, Zheng L, Zheng XX, Hu C, Hu X, Shen X, Chen W., Free PMC Article | 02/16/2023 |
| A novel membrane targeting domain mediates the endosomal or Golgi localization specificity of small GTPases Rab22 and Rab31. | A novel membrane targeting domain mediates the endosomal or Golgi localization specificity of small GTPases Rab22 and Rab31.
Banworth MJ, Liang Z, Li G., Free PMC Article | 10/22/2022 |
| Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency. | Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency.
Jalagadugula G, Mao G, Goldfinger LE, Wurtzel J, Del Carpio-Cano F, Lambert MP, Estevez B, French DL, Poncz M, Rao AK., Free PMC Article | 09/24/2022 |
| LncRNA HOXA10-AS Activated by E2F1 Facilitates Proliferation and Migration of Nasopharyngeal Carcinoma Cells Through Sponging miR-582-3p to Upregulate RAB31. | LncRNA HOXA10-AS Activated by E2F1 Facilitates Proliferation and Migration of Nasopharyngeal Carcinoma Cells Through Sponging miR-582-3p to Upregulate RAB31.
Wang X, Nie P, Zhu D. | 04/9/2022 |
| Rab31-dependent regulation of transforming growth factor ss expression in breast cancer cells. | Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells.
Soelch S, Beaufort N, Loessner D, Kotzsch M, Reuning U, Luther T, Kirchner T, Magdolen V., Free PMC Article | 03/26/2022 |
| RAB31 marks and controls an ESCRT-independent exosome pathway. | RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T., Free PMC Article | 12/25/2021 |
| High expression of Rab31 confers a poor prognosis and enhances cell proliferation and invasion in oral squamous cell carcinoma. | High expression of Rab31 confers a poor prognosis and enhances cell proliferation and invasion in oral squamous cell carcinoma.
Li X, Zhu F, Liu Z, Tang X, Han Y, Jiang J, Ma C, He Y., Free PMC Article | 10/16/2021 |
| Shigella escapes lysosomal degradation through inactivation of Rab31 by IpaH4.5. | Shigella escapes lysosomal degradation through inactivation of Rab31 by IpaH4.5.
Sun J, Wang X, Lin H, Wan L, Chen J, Yang X, Li D, Zhang Y, He X, Wang B, Dong M, Zhong H, Wei C. | 08/7/2021 |
| Upregulation of Rab31 is associated with poor prognosis and promotes colorectal carcinoma proliferation via the mTOR/p70S6K/Cyclin D1 signalling pathway. | Upregulation of Rab31 is associated with poor prognosis and promotes colorectal carcinoma proliferation via the mTOR/p70S6K/Cyclin D1 signalling pathway.
Yang L, Tian X, Chen X, Lin X, Tang C, Gao Y, Chen S, Ge Z. | 09/19/2020 |
| The impaired EGFR signaling and its effects on epidermal differentiation were also observed in familial AI patients and Ncstn(DeltaKC) mice. Thus, our study showed that miR-30a-3p/RAB31/EGFR signaling pathway may play a key role in the pathogenesis of familial AI with NCSTN mutations. | Nicastrin/miR-30a-3p/RAB31 Axis Regulates Keratinocyte Differentiation by Impairing EGFR Signaling in Familial Acne Inversa.
He Y, Xu H, Li C, Zhang X, Zhou P, Xiao X, Zhang W, Wu Y, Zeng R, Wang B. | 11/2/2019 |
| Findings identified a breast cancer (BC) susceptibility SNP, rs6506689 G>T in RAB31. Functional analysis of this germline mutation suggested that the rs6506689-T allele may increase FOXA1-binding affinity and up-regulates the expression of RAB31, ultimately promoting the development of BC. | Integrative functional genomics identifies regulatory genetic variant modulating RAB31 expression and altering susceptibility to breast cancer.
Zhang Y, Yang B, Cheng X, Liu L, Zhu Y, Gong Y, Yang Y, Tian J, Peng X, Zou D, Yang L, Mei S, Wang X, Lou J, Ke J, Li J, Gong J, Chang J, Yuan P, Zhong R. | 05/18/2019 |
| the role of Rab31 in cancer progression, is reported. | The Critical Role of Rab31 in Cell Proliferation and Apoptosis in Cancer Progression.
Pan Y, Zhang Y, Chen L, Liu Y, Feng Y, Yan J. | 01/13/2018 |
| this study provides the evidence of Rab31 overexpression in HCC, and Rab31 is potentially used as a novel biomarker of poor prognosis in patients with HCC. PI3K/AKT/Bcl-2/BAX axis was involved in Rab31-promoting HCC progression. | Rab31 promoted hepatocellular carcinoma (HCC) progression via inhibition of cell apoptosis induced by PI3K/AKT/Bcl-2/BAX pathway.
Sui Y, Zheng X, Zhao D. | 04/16/2016 |
| Data indicate that early endosome antigen 1 (EEA1) is important for the small GTPase Rab31-mediated enhancement of ligand-bound EGF receptor (EGFR) endocytic trafficking. | Engagement of the small GTPase Rab31 protein and its effector, early endosome antigen 1, is important for trafficking of the ligand-bound epidermal growth factor receptor from the early to the late endosome.
Chua CE, Tang BL., Free PMC Article | 08/9/2014 |
| MUC1-C and Rab31 function in an autoinductive loop that contributes to overexpression of MUC1-C in breast cancer cells. | Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
Jin C, Rajabi H, Pitroda S, Li A, Kharbanda A, Weichselbaum R, Kufe D., Free PMC Article | 03/23/2013 |
| Overexpression of rab31 in breast cancer cells leads to a switch from an invasive to a proliferative phenotype as indicated by an increased cell proliferation, reduced adhesion and invasion in vitro, and a reduced capacity to form lung metastases in vivo. | Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells.
Grismayer B, Sölch S, Seubert B, Kirchner T, Schäfer S, Baretton G, Schmitt M, Luther T, Krüger A, Kotzsch M, Magdolen V., Free PMC Article | 03/23/2013 |
| Neither UPARwt, nor UPAR-del4/5 nor RAB31 mRNA expression levels were found to be prognostic markers in advanced ovarian cancer. | mRNA expression levels of the biological factors uPAR, uPAR-del4/5, and rab31, displaying prognostic value in breast cancer, are not clinically relevant in advanced ovarian cancer.
Kotzsch M, Dorn J, Doetzer K, Schmalfeldt B, Krol J, Baretton G, Kiechle M, Schmitt M, Magdolen V. | 01/28/2012 |
| RIN3 specifically acts as a GEF for Rab31. | Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31.
Kajiho H, Sakurai K, Minoda T, Yoshikawa M, Nakagawa S, Fukushima S, Kontani K, Katada T., Free PMC Article | 09/10/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Rab22B possibly plays role in regulating epidermal growth factor receptor (EGFR) and mannose 6-phosphate receptor (M6PR) transport into late endosomes. | Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.
Ng EL, Ng JJ, Liang F, Tang BL. | 01/21/2010 |
| uPAR-del4/5 and rab31 mRNA represent independent prognostic markers in breast cancer and may be components of different, but possibly associated, tumor-relevant signaling pathways. | Urokinase receptor splice variant uPAR-del4/5-associated gene expression in breast cancer: identification of rab31 as an independent prognostic factor.
Kotzsch M, Sieuwerts AM, Grosser M, Meye A, Fuessel S, Meijer-van Gelder ME, Smid M, Schmitt M, Baretton G, Luther T, Magdolen V, Foekens JA. | 01/21/2010 |
| Thus, Rab22B may have a role in anterograde exit from the trans-Golgi network . | Rab22B's role in trans-Golgi network membrane dynamics.
Ng EL, Wang Y, Tang BL. | 01/21/2010 |