| Identification of the hybrid gene LILRB5-3 by long-read sequencing and implication of its novel signaling function. | Identification of the hybrid gene LILRB5-3 by long-read sequencing and implication of its novel signaling function.
Hirayasu K, Khor SS, Kawai Y, Shimada M, Omae Y, Hasegawa G, Hashikawa Y, Tanimoto H, Ohashi J, Hosomichi K, Tajima A, Nakamura H, Nakamura M, Tokunaga K, Hanayama R, Nagasaki M., Free PMC Article | 09/17/2024 |
| Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans. | Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.
Bashirova AA, Kasprzak W, O'hUigin C, Carrington M., Free PMC Article | 05/25/2023 |
| LilrB3 is a putative cell surface receptor of APOE4. | LilrB3 is a putative cell surface receptor of APOE4.
Zhou J, Wang Y, Huang G, Yang M, Zhu Y, Jin C, Jing D, Ji K, Shi Y., Free PMC Article | 02/11/2023 |
| LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2-cFLIP-NF-kappaB signaling axis. | LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2-cFLIP-NF-κB signaling axis.
Wu G, Xu Y, Schultz RD, Chen H, Xie J, Deng M, Liu X, Gui X, John S, Lu Z, Arase H, Zhang N, An Z, Zhang CC., Free PMC Article | 05/7/2022 |
| Epithelial cells remove precancerous cells by cell competition via MHC class I-LILRB3 interaction. | Epithelial cells remove precancerous cells by cell competition via MHC class I-LILRB3 interaction.
Ayukawa S, Kamoshita N, Nakayama J, Teramoto R, Pishesha N, Ohba K, Sato N, Kozawa K, Abe H, Semba K, Goda N, Fujita Y, Maruyama T. | 11/22/2021 |
| KLRD1, FOSL2 and LILRB3 as potential biomarkers for plaques progression in acute myocardial infarction and stable coronary artery disease. | KLRD1, FOSL2 and LILRB3 as potential biomarkers for plaques progression in acute myocardial infarction and stable coronary artery disease.
Zhang Q, Zheng Y, Ning M, Li T., Free PMC Article | 10/16/2021 |
| Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population. | Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.
Hirayasu K, Sun J, Hasegawa G, Hashikawa Y, Hosomichi K, Tajima A, Tokunaga K, Ohashi J, Hanayama R. | 09/11/2021 |
| LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation. | LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.
Yeboah M, Papagregoriou C, Jones DC, Chan HTC, Hu G, McPartlan JS, Schiött T, Mattson U, Mockridge CI, Tornberg UC, Hambe B, Ljungars A, Mattsson M, Tews I, Glennie MJ, Thirdborough SM, Trowsdale J, Frendeus B, Chen J, Cragg MS, Roghanian A., Free PMC Article | 05/22/2021 |
| The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils. | The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils.
Zhao Y, van Woudenbergh E, Zhu J, Heck AJR, van Kessel KPM, de Haas CJC, Aerts PC, van Strijp JAG, McCarthy AJ. | 09/26/2020 |
| Together, this study identified ILT5 as an immunosuppressive regulator during sepsis, which may provide potential therapeutic strategy for sepsis. | Immunoglobulin-Like Transcript 5 Inhibits Macrophage-Mediated Bacterial Killing and Antigen Presentation During Sepsis.
Ming S, Li M, Wu M, Zhang J, Zhong H, Chen J, Huang Y, Bai J, Huang L, Chen J, Lin Q, Liu J, Tao J, He D, Huang X. | 05/23/2020 |
| Glatiramer Acetate Enhances Myeloid-Derived Suppressor Cell Function via Recognition of Paired Ig-like Receptor B. | Glatiramer Acetate Enhances Myeloid-Derived Suppressor Cell Function via Recognition of Paired Ig-like Receptor B.
van der Touw W, Kang K, Luan Y, Ma G, Mai S, Qin L, Bian G, Zhang R, Mungamuri SK, Hu HM, Zhang CC, Aaronson SA, Feldmann M, Yang WC, Chen SH, Pan PY., Free PMC Article | 07/6/2019 |
| RPS9/LILRB3 (rs11666543) was associated with Takayasu arteritis. | Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
Renauer PA, Saruhan-Direskeneli G, Coit P, Adler A, Aksu K, Keser G, Alibaz-Oner F, Aydin SZ, Kamali S, Inanc M, Carette S, Cuthbertson D, Hoffman GS, Akar S, Onen F, Akkoc N, Khalidi NA, Koening C, Karadag O, Kiraz S, Langford CA, Maksimowicz-McKinnon K, McAlear CA, Ozbalkan Z, Ates A, Karaaslan Y, Duzgun N, Monach PA, Ozer HT, Erken E, Ozturk MA, Yazici A, Cefle A, Onat AM, Kisacik B, Pagnoux C, Kasifoglu T, Seyahi E, Fresko I, Seo P, Sreih AG, Warrington KJ, Ytterberg SR, Cobankara V, Cunninghame-Graham DS, Vyse TJ, Pamuk ON, Tunc SE, Dalkilic E, Bicakcigil M, Yentur SP, Wren JD, Merkel PA, Direskeneli H, Sawalha AH., Free PMC Article | 07/4/2015 |
| Blockade of LILRB1 and LILRB3 receptors by monoclonal antibodies or short interfering RNA (siRNA) abrogated the specific antigen-presenting properties of dendritic cells, implying an important regulatory role of these molecules. | Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers.
Huang J, Burke PS, Cung TD, Pereyra F, Toth I, Walker BD, Borges L, Lichterfeld M, Yu XG., Free PMC Article | 09/27/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium., Free PMC Article | 09/15/2010 |
| LILRB3 is expressed on cultured osteoclast precursor cells derived from peripheral blood monocytes and plays a regulatory role in the development of osteoclasts. | Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development.
Mori Y, Tsuji S, Inui M, Sakamoto Y, Endo S, Ito Y, Fujimura S, Koga T, Nakamura A, Takayanagi H, Itoi E, Takai T. | 01/21/2010 |
| Progenitor mast cells expressed cell surface inhibitory LILRB3. Mature cord-blood-derived mast cells had detectable mRNA encoding multiple LILRs, none were expressed on the cell surface. | Differential expression of leukocyte immunoglobulin-like receptors on cord-blood-derived human mast cell progenitors and mature mast cells.
Tedla N, Lee CW, Borges L, Geczy CL, Arm JP. | 01/21/2010 |
| Coligation of LIR3 to LIR7 or to FcepsilonRI by means of a second monoclonal antibody significantly inhibited net histamine release, cysLT production, and IL-4 generation. LIR3 is counter-regulatory for both adaptive and innate receptors suggests. | Leukocyte immunoglobulin-like receptors: novel innate receptors for human basophil activation and inhibition.
Sloane DE, Tedla N, Awoniyi M, Macglashan DW Jr, Borges L, Austen KF, Arm JP. | 01/21/2010 |