| FATP2 regulates non-small cell lung cancer by mediating lipid metabolism through ACSL1. | FATP2 regulates non-small cell lung cancer by mediating lipid metabolism through ACSL1.
Chen Y, Zhao Y, Deng Y, Yang Y, Xu L, Fu J. | 06/25/2023 |
| Feedback loop between fatty acid transport protein 2 and receptor interacting protein 3 pathways promotes polymorphonuclear neutrophil myeloid-derived suppressor cells-potentiated suppressive immunity in bladder cancer. | Feedback loop between fatty acid transport protein 2 and receptor interacting protein 3 pathways promotes polymorphonuclear neutrophil myeloid-derived suppressor cells-potentiated suppressive immunity in bladder cancer.
Shi X, Pang S, Zhou J, Yan G, Sun J, Tan W. | 12/10/2022 |
| Upregulated SLC27A2/FATP2 in differentiated thyroid carcinoma promotes tumor proliferation and migration. | Upregulated SLC27A2/FATP2 in differentiated thyroid carcinoma promotes tumor proliferation and migration.
Feng K, Ma R, Li H, Yin K, Du G, Chen X, Liu Z, Yin D., Free PMC Article | 03/19/2022 |
| Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis. | Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Chen Y, Yan Q, Lv M, Song K, Dai Y, Huang Y, Zhang L, Zhang C, Gao H., Free PMC Article | 05/1/2021 |
| mouse and human polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) exclusively upregulate fatty acid transport protein 2 (FATP2); FATP2 mediates the acquisition of immunosuppressive activity by PMN-MDSCs and represents a target to inhibit the functions of PMN-MDSCs selectively and to improve the efficiency of cancer therapy | Fatty acid transport protein 2 reprograms neutrophils in cancer.
Veglia F, Tyurin VA, Blasi M, De Leo A, Kossenkov AV, Donthireddy L, To TKJ, Schug Z, Basu S, Wang F, Ricciotti E, DiRusso C, Murphy ME, Vonderheide RH, Lieberman PM, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Lin C, Nefedova Y, Black P, Kagan VE, Gabrilovich DI., Free PMC Article | 09/14/2019 |
| In overweight/obese pregnancies, the increased FATP2 placental expression could contribute to increased fatty acid delivery to the fetus. | Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.
Lager S, Ramirez VI, Gaccioli F, Jang B, Jansson T, Powell TL., Free PMC Article | 01/14/2017 |
| In mice Grassofermata decreased absorption of (13)C-oleate demonstrating its potential as a therapeutic agent. | Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity.
Saini N, Black PN, Montefusco D, DiRusso CC., Free PMC Article | 11/28/2015 |
| Protective effects of breastfeeding are reflected in higher expression levels of SLC27A2, FASN, PPARalpha and INSR in blood cells. | Influence of breastfeeding on blood-cell transcript-based biomarkers of health in children.
Priego T, Sánchez J, Picó C, Ahrens W, Bammann K, De Henauw S, Fraterman A, Iacoviello L, Lissner L, Molnár D, Moreno LA, Siani A, Tornaritis M, Veidebaum T, Palou A, IDEFICS Consortium. | 07/25/2015 |
| these data support the conclusion that FATP2 has a dual function in the pathways linking the transport and activation of exogenous fatty acids. | Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids.
Melton EM, Cerny RL, DiRusso CC, Black PN., Free PMC Article | 02/15/2014 |
| even though hypoxia regulates the expression of FATP2 and FATP4 in human trophoblasts, mouse Fatp2 and Fatp4 are not essential for intrauterine fetal growth. | The expression and function of fatty acid transport protein-2 and -4 in the murine placenta.
Mishima T, Miner JH, Morizane M, Stahl A, Sadovsky Y., Free PMC Article | 02/25/2012 |
| FATP2a functions in fatty acid transport and activation and provides specificity toward n-3 fatty acids in which the corresponding n-3 acyl-CoAs are preferentially trafficked into acyl-CoA pools destined for phosphatidylinositol incorporation | Human fatty acid transport protein 2a/very long chain acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol.
Melton EM, Cerny RL, Watkins PA, DiRusso CC, Black PN., Free PMC Article | 10/29/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F. | 12/5/2010 |
| Genome-wide association study of gene-disease association. (HuGE Navigator) | Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR, Briley JD, Borrie M, Coletta N, Delisle R, Dhalla D, Ehm MG, Feldman HH, Fornazzari L, Gauthier S, Goodgame N, Guzman D, Hammond S, Hollingworth P, Hsiung GY, Johnson J, Kelly DD, Keren R, Kertesz A, King KS, Lovestone S, Loy-English I, Matthews PM, Owen MJ, Plumpton M, Pryse-Phillips W, Prinjha RK, Richardson JC, Saunders A, Slater AJ, St George-Hyslop PH, Stinnett SW, Swartz JE, Taylor RL, Wherrett J, Williams J, Yarnall DP, Gibson RA, Irizarry MC, Middleton LT, Roses AD. | 12/2/2009 |