Defining Requirements for Heme Binding in PGRMC1 and Identifying Key Elements that Influence Protein Dimerization. | Defining Requirements for Heme Binding in PGRMC1 and Identifying Key Elements that Influence Protein Dimerization. Badve P, Meier KK. | 04/12/2024 |
Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization. | Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization. Liu H, Franken A, Bielfeld AP, Fehm T, Niederacher D, Cheng Z, Neubauer H, Stamm N., Free PMC Article | 02/7/2024 |
Progesterone receptor membrane component 1 facilitates Ca[2+] signal amplification between endosomes and the endoplasmic reticulum. | Progesterone receptor membrane component 1 facilitates Ca(2+) signal amplification between endosomes and the endoplasmic reticulum. Gunaratne GS, Kumar S, Lin-Moshier Y, Slama JT, Brailoiu E, Patel S, Walseth TF, Marchant JS., Free PMC Article | 01/9/2024 |
Downregulation of PGRMC1 accelerates differentiation and fusion of a human trophoblast cell line. | Downregulation of PGRMC1 accelerates differentiation and fusion of a human trophoblast cell line. Tsuru A, Yoshie M, Suzuki M, Mochizuki H, Kametaka S, Ohmaru-Nakanishi T, Azumi M, Kusama K, Kato K, Tamura K. | 12/22/2023 |
Regulatory action of PGRMC1 on cyclic AMP-mediated COX2 expression in human endometrial cells. | Regulatory action of PGRMC1 on cyclic AMP-mediated COX2 expression in human endometrial cells. Tsuru A, Yoshie M, Negishi R, Mukoyama T, Yonekawa R, Kojima J, Azumi M, Kusama K, Nishi H, Tamura K. | 11/30/2023 |
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma. | Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma. Dumitru CA, Schröder H, Schäfer FTA, Aust JF, Kreße N, Siebert CLR, Stein KP, Haghikia A, Wilkens L, Mawrin C, Sandalcioglu IE., Free PMC Article | 11/16/2023 |
Expression of PGRMC1 in patients with polycystic ovary syndrome and its molecular mechanism for regulating ovarian granulosa cell apoptosis and glucolipid metabolism. | Expression of PGRMC1 in patients with polycystic ovary syndrome and its molecular mechanism for regulating ovarian granulosa cell apoptosis and glucolipid metabolism. Zhou J, Chen Z, Li J, Deng Q, Peng X, Li L., Free PMC Article | 07/5/2023 |
PGRMC1 promotes triple-negative breast cancer cell growth via suppressing ferroptosis. | PGRMC1 promotes triple-negative breast cancer cell growth via suppressing ferroptosis. Zhao Y, Ruan X, Cheng J, Xu X, Gu M, Mueck AO. | 03/24/2023 |
Spatiotemporal expression pattern of Progesterone Receptor Component (PGRMC) 1 in endometrium from patients with or without endometriosis or adenomyosis. | Spatiotemporal expression pattern of Progesterone Receptor Component (PGRMC) 1 in endometrium from patients with or without endometriosis or adenomyosis. Thieffry C, Van Wynendaele M, Samain L, Tyteca D, Pierreux C, Marbaix E, Henriet P. | 10/8/2022 |
PGRMC1 Regulates Cellular Senescence via Modulating FOXO1 Expression in Decidualizing Endometrial Stromal Cells. | PGRMC1 Regulates Cellular Senescence via Modulating FOXO1 Expression in Decidualizing Endometrial Stromal Cells. Tsuru A, Yoshie M, Kojima J, Yonekawa R, Azumi M, Kusama K, Nishi H, Tamura K., Free PMC Article | 09/3/2022 |
Molecular Docking and In Silico Simulation of Trichinella spiralis Membrane-Associated Progesterone Receptor Component 2 (Ts-MAPRC2) and Its Interaction with Human PGRMC1. | Molecular Docking and In Silico Simulation of Trichinella spiralis Membrane-Associated Progesterone Receptor Component 2 (Ts-MAPRC2) and Its Interaction with Human PGRMC1. Aleem MT, Khan A, Wen Z, Yu Z, Li K, Shaukat A, Chen C, -Rehman TU, Lu M, Xu L, Song X, Li X, Yan R., Free PMC Article | 07/9/2022 |
The role of progesterone receptor membrane component (PGRMC) in the endometrium. | The role of progesterone receptor membrane component (PGRMC) in the endometrium. Velázquez Hernández DM, Vázquez-Martínez ER, Camacho-Arroyo I. | 07/2/2022 |
A 127 kb truncating deletion of PGRMC1 is a novel cause of X-linked isolated paediatric cataract. | A 127 kb truncating deletion of PGRMC1 is a novel cause of X-linked isolated paediatric cataract. Jones JL, Corbett MA, Yeaman E, Zhao D, Gecz J, Gasperini RJ, Charlesworth JC, Mackey DA, Elder JE, Craig JE, Burdon KP., Free PMC Article | 03/19/2022 |
Metastasis enhancer PGRMC1 boosts store-operated Ca(2+) entry by uncoiling Ca(2+) sensor STIM1 for focal adhesion turnover and actomyosin formation. | Metastasis enhancer PGRMC1 boosts store-operated Ca(2+) entry by uncoiling Ca(2+) sensor STIM1 for focal adhesion turnover and actomyosin formation. Lee SK, Kweon YC, Lee AR, Lee YY, Park CY. | 02/19/2022 |
PGRMC1 Exerts Its Function of Anti-Influenza Virus in the Central Nervous System. | PGRMC1 Exerts Its Function of Anti-Influenza Virus in the Central Nervous System. Huang K, Zhang Y, Gong W, Yang Y, Jiang L, Zhao L, Yang Y, Wei Y, Li C, He X, Sun X, Zou Z, Jin M., Free PMC Article | 02/5/2022 |
Absence of progesterone receptor membrane component 1 reduces migration and metastasis of breast cancer. | Absence of progesterone receptor membrane component 1 reduces migration and metastasis of breast cancer. Lee SR, Lee YH, Jo SL, Heo JH, Kim G, Lee GS, An BS, Baek IJ, Hong EJ., Free PMC Article | 01/29/2022 |
The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide. | The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide. Wang-Eckhardt L, Becker I, Eckhardt M., Free PMC Article | 01/22/2022 |
AG-205 Upregulates Enzymes Involved in Cholesterol Biosynthesis and Steroidogenesis in Human Endometrial Cells Independently of PGRMC1 and Related MAPR Proteins. | AG-205 Upregulates Enzymes Involved in Cholesterol Biosynthesis and Steroidogenesis in Human Endometrial Cells Independently of PGRMC1 and Related MAPR Proteins. Thieffry C, Van Wynendaele M, Aynaci A, Maja M, Dupuis C, Loriot A, Marbaix E, Henriet P., Free PMC Article | 01/15/2022 |
Loss of beta-Arrestins or six Galpha proteins in HEK293 cells caused Warburg effect and prevented progesterone-induced rapid proteasomal degradation of progesterone receptor membrane component 1. | Loss of β-Arrestins or six Gα proteins in HEK293 cells caused Warburg effect and prevented progesterone-induced rapid proteasomal degradation of progesterone receptor membrane component 1. Sabbir MG, Inoue A, Taylor CG, Zahradka P. | 12/18/2021 |
Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism. | Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism. McGuire MR, Mukhopadhyay D, Myers SL, Mosher EP, Brookheart RT, Kammers K, Sehgal A, Selen ES, Wolfgang MJ, Bumpus NN, Espenshade PJ., Free PMC Article | 12/18/2021 |
Deciphering the Role of PGRMC1 During Human Decidualization Using an In Vitro Approach. | Deciphering the Role of PGRMC1 During Human Decidualization Using an In Vitro Approach. Salsano S, González-Martín R, Quiñonero A, Pérez-Debén S, Domínguez F. | 10/23/2021 |
Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. | Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. Huang HY, Chou HC, Law CH, Chang WT, Wen TN, Liao EC, Lin MW, Lin LH, Wei YS, Tsai YT, Chen HY, Tan KT, Kuo WH, Ko ML, Chang SJ, Lee YR, Chan HL., Free PMC Article | 09/18/2021 |
Crosstalk between progesterone receptor membrane component 1 and estrogen receptor alpha promotes breast cancer cell proliferation. | Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation. Pedroza DA, Subramani R, Tiula K, Do A, Rashiraj N, Galvez A, Chatterjee A, Bencomo A, Rivera S, Lakshmanaswamy R. | 08/21/2021 |
The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Abeta42 and Its Protein Aggregates. | The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates. Riad A, Lengyel-Zhand Z, Zeng C, Weng CC, Lee VM, Trojanowski JQ, Mach RH., Free PMC Article | 06/5/2021 |
Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling. | Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling. Pedroza DA, Rajamanickam V, Subramani R, Bencomo A, Galvez A, Lakshmanaswamy R., Free PMC Article | 03/27/2021 |