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    SRSF10 serine and arginine rich splicing factor 10 [ Homo sapiens (human) ]

    Gene ID: 10772, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Identification of SRSF10 as a promising prognostic biomarker with functional significance among SRSFs for glioma.

    Identification of SRSF10 as a promising prognostic biomarker with functional significance among SRSFs for glioma.
    An W, Yang Q, Xi Y, Pan H, Huang H, Chen Q, Wang Y, Hua D, Shi C, Wang Q, Sun C, Luo W, Li X, Yu S, Zhou X.

    02/6/2024
    lncR-GAS5 upregulates the splicing factor SRSF10 to impair endothelial autophagy, leading to atherogenesis.

    lncR-GAS5 upregulates the splicing factor SRSF10 to impair endothelial autophagy, leading to atherogenesis.
    Fan Y, Zhang Y, Zhao H, Liu W, Xu W, Jiang L, Xu R, Zheng Y, Tang X, Li X, Zhao L, Liu X, Hong Y, Lin Y, Chen H, Zhang Y.

    06/2/2023
    SRSF10 stabilizes CDC25A by triggering exon 6 skipping to promote hepatocarcinogenesis.

    SRSF10 stabilizes CDC25A by triggering exon 6 skipping to promote hepatocarcinogenesis.
    Liu X, Zheng Y, Xiao M, Chen X, Zhu Y, Xu C, Wang F, Liu Z, Cao K., Free PMC Article

    12/31/2022
    The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma.

    The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma.
    Chang C, Rajasekaran M, Qiao Y, Dong H, Wang Y, Xia H, Deivasigamani A, Wu M, Sekar K, Gao H, Sun M, Niu Y, Li Q, Tao L, Yan Z, Wang M, Chen S, Zhao S, Chen D, Li L, Yang F, Gao H, Chen B, Su L, Xu L, Chen Y, Seshachalam VP, Chen G, Gunaratne J, Hong W, Shi J, Chen G, Grierson DS, Chabot B, Xie T, Hui KM, Chen J., Free PMC Article

    04/9/2022
    Identification of SRSF10 as a regulator of SMN2 ISS-N1.

    Identification of SRSF10 as a regulator of SMN2 ISS-N1.
    Frederiksen SB, Holm LL, Larsen MR, Doktor TK, Andersen HS, Hastings ML, Hua Y, Krainer AR, Andresen BS., Free PMC Article

    04/9/2022
    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression.

    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression.
    Meinke S, Goldammer G, Weber AI, Tarabykin V, Neumann A, Preussner M, Heyd F., Free PMC Article

    03/27/2021
    SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.

    SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
    Liu X, Shen S, Zhu L, Su R, Zheng J, Ruan X, Shao L, Wang D, Yang C, Liu Y., Free PMC Article

    03/6/2021
    Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production.

    Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production.
    Chabrolles H, Auclair H, Vegna S, Lahlali T, Pons C, Michelet M, Couté Y, Belmudes L, Chadeuf G, Kim Y, Di Bernardo A, Jalaguier P, Cosset FL, Fusil F, Rivoire M, Arnold LD, Lopatin U, Combet C, Zoulim F, Grierson D, Chabot B, Lucifora J, Durantel D, Salvetti A., Free PMC Article

    02/13/2021
    Moreover, SRSF10, hnRNP A1/A2 and Sam68 collaborate to drive the DNA damage-induced splicing response of several transcripts that produce components implicated in apoptosis, cell-cycle control and DNA repair.

    hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.
    Cloutier A, Shkreta L, Toutant J, Durand M, Thibault P, Chabot B., Free PMC Article

    12/22/2018
    DNA damage co-opts SRSF10 to control splicing decisions in transcripts encoding components involved in DNA repair, cell-cycle control, and apoptosis.

    SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors.
    Shkreta L, Toutant J, Durand M, Manley JL, Chabot B., Free PMC Article

    11/26/2017
    Results show that YTHDC1 promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor SRSF3 while blocking SRSF10 mRNA binding.

    Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
    Xiao W, Adhikari S, Dahal U, Chen YS, Hao YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, Wang X, Ma HL, Huang CM, Yang Y, Huang N, Jiang GB, Wang HL, Zhou Q, Wang XJ, Zhao YL, Yang YG.

    07/30/2016
    SRSF10 is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells

    BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.
    Zhou X, Li X, Cheng Y, Wu W, Xie Z, Xi Q, Han J, Wu G, Fang J, Feng Y.

    08/8/2015
    In colorectal cancer, NSSR1 was highly expressed in the nucleus of tumor cells.

    [Expression of neural salient serine-/arginine-rich protein 1 (NSSR1) in colorectal cancer].
    Zhang W, Shen Q, Shen JX.

    01/14/2012
    Splicing thermotolerance is acquired through maintenance of SRSF10 phosphorylation and that this is mediated at least in part by Hsp27.

    Heat shock-induced SRSF10 dephosphorylation displays thermotolerance mediated by Hsp27.
    Shi Y, Nishida K, Campigli Di Giammartino D, Manley JL., Free PMC Article

    02/26/2011
    Data show that SFRS13A expression was significantly associated with LDLR splicing efficiency in vivo.

    Role of SFRS13A in low-density lipoprotein receptor splicing.
    Ling IF, Estus S., Free PMC Article

    10/4/2010
    SRp38 plays a crucial role in cell survival under stress conditions by inhibiting the splicing machinery

    Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock.
    Shin C, Feng Y, Manley JL.

    01/21/2010
    SRp38 contains two arginine- and serine-rich domains (RS), one of which has a unique, second-step repression activity, while both function together as a splicing repression domain.

    Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins.
    Shin C, Kleiman FE, Manley JL., Free PMC Article

    01/21/2010
    found to be dephosphorylated specifically in mitotic cells; show that dephosphorylated SRp38 is required for the observed splicing repression

    The SR protein SRp38 represses splicing in M phase cells.
    Shin C, Manley JL.

    01/21/2010
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