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    NFAT5 nuclear factor of activated T cells 5 [ Homo sapiens (human) ]

    Gene ID: 10725, updated on 7-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1alpha Activity in Ishikawa and HEC1a Cells.

    Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells.
    Okumura T, Raja Xavier JP, Pasternak J, Yang Z, Hang C, Nosirov B, Singh Y, Admard J, Brucker SY, Kommoss S, Takeda S, Staebler A, Lang F, Salker MS., Free PMC Article

    05/21/2024
    TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells.

    TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells.
    Song HJ, Kim YH, Choi HN, Kim T, Kim SJ, Kang MW, Lee SD., Free PMC Article

    03/6/2024
    TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation.

    TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation.
    Palahati A, Luo Y, Qin L, Duan Y, Zhang M, Gan H, Zhai X., Free PMC Article

    02/28/2024
    TonEBP expression is essential in the IL-1beta-induced migration and invasion of human A549 lung cancer cells.

    TonEBP expression is essential in the IL-1β-induced migration and invasion of human A549 lung cancer cells.
    Song HJ, Kim T, Choi HN, Kim SJ, Lee SD., Free PMC Article

    01/10/2024
    SAFB2 Inhibits the Progression of Breast Cancer by Suppressing the Wnt/beta-Catenin Signaling Pathway via NFAT5.

    SAFB2 Inhibits the Progression of Breast Cancer by Suppressing the Wnt/β-Catenin Signaling Pathway via NFAT5.
    Zhen H, Yao Y, Yang H.

    08/23/2023
    Associations of the Methylation Levels of NFAT5, PVT1, RPS6KA1, and MIB1 with Steroid-Resistant Asthma.

    Associations of the Methylation Levels of NFAT5, PVT1, RPS6KA1, and MIB1 with Steroid-Resistant Asthma.
    Chen L, Wang W, Leng Q, Cong L, Wu C, Yang X.

    08/13/2022
    NFAT5 Controls the Integrity of Epidermis.

    NFAT5 Controls the Integrity of Epidermis.
    Muhammad K, Xavier D, Klein-Hessling S, Azeem M, Rauschenberger T, Murti K, Avots A, Goebeler M, Klein M, Bopp T, Sielaff M, Tenzer S, Möckel S, Aramburu J, López-Rodríguez C, Kerstan A, Serfling E., Free PMC Article

    02/19/2022
    Circular RNA_0037128 aggravates high glucose-induced damage in HK-2 cells via regulation of microRNA-497-5p/nuclear factor of activated T cells 5 axis.

    Circular RNA_0037128 aggravates high glucose-induced damage in HK-2 cells via regulation of microRNA-497-5p/nuclear factor of activated T cells 5 axis.
    Feng T, Li W, Li T, Jiao W, Chen S., Free PMC Article

    02/19/2022
    TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc.

    TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc.
    Snuggs JW, Tessier S, Bunning RAB, Shapiro IM, Risbud MV, Le Maitre CL., Free PMC Article

    11/22/2021
    The TLR-2/TonEBP signaling pathway regulates 29-kDa fibronectin fragment-dependent expression of matrix metalloproteinases.

    The TLR-2/TonEBP signaling pathway regulates 29-kDa fibronectin fragment-dependent expression of matrix metalloproteinases.
    Hwang HS, Lee MH, Kim HA., Free PMC Article

    11/13/2021
    PARP1-mediated PARylation of TonEBP prevents R-loop-associated DNA damage.

    PARP1-mediated PARylation of TonEBP prevents R-loop-associated DNA damage.
    Ye BJ, Kang HJ, Lee-Kwon W, Kwon HM, Choi SY.

    10/16/2021
    Potential Role of Gene Regulator NFAT5 in the Pathogenesis of Diabetes Mellitus.

    Potential Role of Gene Regulator NFAT5 in the Pathogenesis of Diabetes Mellitus.
    Cen L, Xing F, Xu L, Cao Y., Free PMC Article

    08/28/2021
    Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells.

    Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells.
    Kappert L, Ruzicka P, Kutikhin A, De La Torre C, Fischer A, Hecker M, Arnold C, Korff T.

    08/28/2021
    NFAT5 Regulated by STUB1, Facilitates Malignant Cell Survival and p38 MAPK Activation by Upregulating AQP5 in Chronic Lymphocytic Leukemia.

    NFAT5 Regulated by STUB1, Facilitates Malignant Cell Survival and p38 MAPK Activation by Upregulating AQP5 in Chronic Lymphocytic Leukemia.
    Chen BL, Li Y, Xu S, Nie Y, Zhang J.

    08/21/2021
    The Role of Nuclear Factor of Activated T Cells 5 in Hyperosmotic Stress-Exposed Human Lens Epithelial Cells.

    The Role of Nuclear Factor of Activated T Cells 5 in Hyperosmotic Stress-Exposed Human Lens Epithelial Cells.
    Kim GN, Hah YS, Seong H, Yoo WS, Choi MY, Cho HY, Yun SP, Kim SJ., Free PMC Article

    07/17/2021
    APLNR stimulates the development of glioma via the NFAT5/AKT feedback loop.

    APLNR stimulates the development of glioma via the NFAT5/AKT feedback loop.
    Zhang ZP, Sun XQ, Yuan SJ.

    06/26/2021
    NFAT5-Mediated Signalling Pathways in Viral Infection and Cardiovascular Dysfunction.

    NFAT5-Mediated Signalling Pathways in Viral Infection and Cardiovascular Dysfunction.
    Zhao G, Aghakeshmiri S, Chen YT, Zhang HM, Yip F, Yang D., Free PMC Article

    06/19/2021
    Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance.

    Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance.
    Lee JH, Suh JH, Kang HJ, Choi SY, Jung SW, Lee-Kwon W, Park SA, Kim H, Ye BJ, Yoo EJ, Jeong GW, Park NH, Kwon HM., Free PMC Article

    06/12/2021
    MiR-223/NFAT5 signaling suppresses arterial smooth muscle cell proliferation and motility in vitro.

    MiR-223/NFAT5 signaling suppresses arterial smooth muscle cell proliferation and motility in vitro.
    Su F, Shi M, Zhang J, Zheng Q, Wang H, Li X, Chen J., Free PMC Article

    05/29/2021
    NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium.

    NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium.
    Fan C, Asico LD, Villar VAM, Hunt J, Cuevas S, Armando I, Jose PA, Konkalmatt PR., Free PMC Article

    05/15/2021
    Elevation of hypertonicityinduced protein NFAT5 promotes apoptosis of human umbilical vein endothelial cells through the NFkappaB pathway.

    Elevation of hypertonicity‑induced protein NFAT5 promotes apoptosis of human umbilical vein endothelial cells through the NF‑κB pathway.
    Xie X, Huang C, Xu D, Liu Y, Hu M, Long J, Fang X.

    05/8/2021
    NFAT5 promotes arteriogenesis via MCP-1-dependent monocyte recruitment.

    NFAT5 promotes arteriogenesis via MCP-1-dependent monocyte recruitment.
    Lin XC, Pan M, Zhu LP, Sun Q, Zhou ZS, Li CC, Zhang GG., Free PMC Article

    04/24/2021
    Up-Regulation of Nfat5 mRNA and Fzd4 mRNA as a Marker of Poor Outcome in Neonatal Hypoxic-Ischemic Encephalopathy.

    Up-Regulation of Nfat5 mRNA and Fzd4 mRNA as a Marker of Poor Outcome in Neonatal Hypoxic-Ischemic Encephalopathy.
    O'Sullivan MP, Casey S, Finder M, Ahearne C, Clarke G, Hallberg B, Boylan GB, Murray DM.

    04/17/2021
    Identification of prognostic biomarkers and drug target prediction for colon cancer according to a competitive endogenous RNA network.

    Identification of prognostic biomarkers and drug target prediction for colon cancer according to a competitive endogenous RNA network.
    Hu D, Zhang B, Yu M, Shi W, Zhang L., Free PMC Article

    03/20/2021
    NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment.

    NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment.
    Yoshimoto S, Morita H, Matsuda M, Katakura Y, Hirata M, Hashimoto S., Free PMC Article

    03/20/2021
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