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    CFL1 cofilin 1 [ Homo sapiens (human) ]

    Gene ID: 1072, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Impact of siRNA-Mediated Cofilin-1 Knockdown and Obesity Associated Microenvironment on the Motility of Natural Killer Cells.

    Impact of siRNA-Mediated Cofilin-1 Knockdown and Obesity Associated Microenvironment on the Motility of Natural Killer Cells.
    Griesler B, Hölzel M, Oswald J, Fänder J, Fischer T, Büttner M, Quandt D, Bähr I, Jasinski-Bergner S, Bazwinsky-Wutschke I, Kielstein H.

    10/25/2024
    CircCFL1 Promotes TNBC Stemness and Immunoescape via Deacetylation-Mediated c-Myc Deubiquitylation to Facilitate Mutant TP53 Transcription.

    CircCFL1 Promotes TNBC Stemness and Immunoescape via Deacetylation-Mediated c-Myc Deubiquitylation to Facilitate Mutant TP53 Transcription.
    Wang Z, Li Y, Yang J, Sun Y, He Y, Wang Y, Liang Y, Chen X, Chen T, Han D, Zhang N, Chen B, Zhao W, Wang L, Luo D, Yang Q., Free PMC Article

    10/1/2024
    FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortex.

    FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortex.
    Falace A, Corbieres L, Palminha C, Guarnieri FC, Schaller F, Buhler E, Tuccari di San Carlo C, Montheil A, Watrin F, Manent JB, Represa A, de Chevigny A, Pallesi-Pocachard E, Cardoso C.

    07/1/2024
    The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1.

    The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1.
    Ullo MF, D'Amico AE, Lavenus SB, Logue JS., Free PMC Article

    05/23/2024
    Neuronal CFL1 upregulation in head and neck squamous cell carcinoma enhances tumor-nerve crosstalk and promotes tumor growth.

    Neuronal CFL1 upregulation in head and neck squamous cell carcinoma enhances tumor-nerve crosstalk and promotes tumor growth.
    Liu R, Wang C, Sun Z, Shi X, Zhang Z, Luo J.

    04/25/2024
    Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail.

    Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail.
    Sexton JA, Potchernikov T, Bibeau JP, Casanova-Sepúlveda G, Cao W, Lou HJ, Boggon TJ, De La Cruz EM, Turk BE., Free PMC Article

    03/1/2024
    CFL1 restores the migratory capacity of bone marrow mesenchymal stem cells in primary Sjogren's syndrome by regulating CCR1 expression.

    CFL1 restores the migratory capacity of bone marrow mesenchymal stem cells in primary Sjögren's syndrome by regulating CCR1 expression.
    Huang M, Zhou P, Hang Y, Wu D, Zhao N, Yao G, Tang X, Sun L.

    02/14/2024
    The Multifaceted Role of Cofilin in Neurodegeneration and Stroke: Insights into Pathogenesis and Targeting as a Therapy.

    The Multifaceted Role of Cofilin in Neurodegeneration and Stroke: Insights into Pathogenesis and Targeting as a Therapy.
    Shehjar F, Almarghalani DA, Mahajan R, Hasan SA, Shah ZA., Free PMC Article

    02/9/2024
    Cofilin promotes tau pathology in Alzheimer's disease.

    Cofilin promotes tau pathology in Alzheimer's disease.
    Yan M, Tang L, Dai L, Lei C, Xiong M, Zhang X, He M, Tian Y, Xiong J, Ke W, Zhang Z, Zhang C, Deng X, Zhang Z.

    10/6/2023
    The Activation of the LIMK/Cofilin Signaling Pathway via Extracellular Matrix-Integrin Interactions Is Critical for the Generation of Mature and Vascularized Cardiac Organoids.

    The Activation of the LIMK/Cofilin Signaling Pathway via Extracellular Matrix-Integrin Interactions Is Critical for the Generation of Mature and Vascularized Cardiac Organoids.
    Noh JM, Choi SC, Song MH, Kim KS, Jun S, Park JH, Kim JH, Kim K, Ko TH, Choi JI, Gim JA, Kim JH, Jang Y, Park Y, Na JE, Rhyu IJ, Lim DS., Free PMC Article

    08/28/2023
    Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells.

    Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells.
    Nakajima M, Kawahara R, Simizu S.

    04/28/2023
    The phosphorylation level of Cofilin-1 is related to the pathological subtypes of gastric cancer.

    The phosphorylation level of Cofilin-1 is related to the pathological subtypes of gastric cancer.
    Kang X, Zhao C, Liu Y, Wang G., Free PMC Article

    11/5/2022
    Estradiol inhibits HIV-1BaL infection and induces CFL1 expression in peripheral blood mononuclear cells and endocervical mucosa.

    Estradiol inhibits HIV-1(BaL) infection and induces CFL1 expression in peripheral blood mononuclear cells and endocervical mucosa.
    Verma N, Mukhopadhyay S, Barnable P, Plagianos MG, Teleshova N., Free PMC Article

    04/30/2022
    Identification of the most damaging nsSNPs in the human CFL1 gene and their functional and structural impacts on cofilin-1 protein.

    Identification of the most damaging nsSNPs in the human CFL1 gene and their functional and structural impacts on cofilin-1 protein.
    Halder SK, Rafi MO, Shahriar EB, Albogami S, El-Shehawi AM, Daullah SMMU, Himel MK, Emran TB.

    03/12/2022
    Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells.

    Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells.
    Li X, Ma G, Guo W, Mu N, Wang Y, Liu X, Su L., Free PMC Article

    02/26/2022
    The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.

    The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.
    Vignier N, Chatzifrangkeskou M, Pinton L, Wioland H, Marais T, Lemaitre M, Le Dour C, Peccate C, Cardoso D, Schmitt A, Wu W, Biferi MG, Naouar N, Macquart C, Beuvin M, Decostre V, Bonne G, Romet-Lemonne G, Worman HJ, Tedesco FS, Jégou A, Muchir A., Free PMC Article

    02/19/2022
    Acidic microenvironment enhances MT1-MMP-mediated cancer cell motility through integrin beta1/cofilin/F-actin axis.

    Acidic microenvironment enhances MT1-MMP-mediated cancer cell motility through integrin β1/cofilin/F-actin axis.
    Liang L, Sui R, Song Y, Zhao Y.

    02/19/2022
    ABL1 and Cofilin1 promote T-cell acute lymphoblastic leukemia cell migration.

    ABL1 and Cofilin1 promote T-cell acute lymphoblastic leukemia cell migration.
    Luo J, Zheng H, Wang S, Li D, Ma W, Wang L, Crabbe MJC.

    02/12/2022
    Effects and mechanisms of FBXO31 on Taxol chemoresistance in esophageal squamous cell carcinoma.

    Effects and mechanisms of FBXO31 on Taxol chemoresistance in esophageal squamous cell carcinoma.
    Lv L, Wang SC, Mo JY, Huang KL, Xu ML, Liu J.

    01/15/2022
    Hypoxia-induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway.

    Hypoxia-induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway.
    Yao B, Li Y, Chen T, Niu Y, Wang Y, Yang Y, Wei X, Liu Q, Tu K., Free PMC Article

    01/15/2022
    Relationship of intracellular proteolysis with CAP1 and cofilin1 in non-small-cell lung cancer.

    Relationship of intracellular proteolysis with CAP1 and cofilin1 in non-small-cell lung cancer.
    Kolegova ES, Kakurina GV, Shashova EE, Yunusova NV, Spirina LV, Sidenko EA, Kostromitskiy DN, Dobrodeev AY, Kondakova IV.

    12/4/2021
    The intrinsic amyloidogenic propensity of cofilin-1 is aggravated by Cys-80 oxidation: A possible link with neurodegenerative diseases.

    The intrinsic amyloidogenic propensity of cofilin-1 is aggravated by Cys-80 oxidation: A possible link with neurodegenerative diseases.
    Kaushik V, Brünnert D, Hanschmann EM, Sharma PK, Anand BG, Kar K, Kateriya S, Goyal P.

    11/27/2021
    Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis.

    Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis.
    Guo W, Guo T, Zhou Q, Long Y, Luo M, Shen Q, Duan W, Ouyang X, Peng H.

    11/13/2021
    ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells.

    ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells.
    Ullo MF, Logue JS., Free PMC Article

    10/9/2021
    Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27(kip1) -mediated growth delay.

    Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27(kip1) -mediated growth delay.
    Tsai CH, Chang CY, Lin BZ, Wu YL, Wu MH, Lin LT, Huang WC, Holz JD, Sheu TJ, Lee JS, Kitsis RN, Tai PH, Lee YJ., Free PMC Article

    09/4/2021
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