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    IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 [ Homo sapiens (human) ]

    Gene ID: 10643, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association of insulin-like growth factor II mrna-binding protein 3 (IMP3) expression with prognostic and morphological factors in endometrial cancer.

    Association of insulin-like growth factor II mrna-binding protein 3 (IMP3) expression with prognostic and morphological factors in endometrial cancer.
    Salum SOR, Candido EB, Domingues MAC, Ojopi EPB, Tonon ÂFS, da Silva-Filho AL., Free PMC Article

    10/3/2024
    METTL5: A Potential Biomarker for Nonsmall Cell Lung Cancer That Promotes Cancer Cell Proliferation by Interacting with IGF2BP3.

    METTL5: A Potential Biomarker for Nonsmall Cell Lung Cancer That Promotes Cancer Cell Proliferation by Interacting with IGF2BP3.
    Gong S, Liu H, Gou H, Sun W.

    09/20/2024
    Oncofetal IGF2BP3-mediated control of microRNA structural diversity in the malignancy of early-stage lung adenocarcinoma.

    Oncofetal IGF2BP3-mediated control of microRNA structural diversity in the malignancy of early-stage lung adenocarcinoma.
    Fujiwara Y, Takahashi RU, Saito M, Umakoshi M, Shimada Y, Koyama K, Yatabe Y, Watanabe SI, Koyota S, Minamiya Y, Tahara H, Kono K, Shiraishi K, Kohno T, Goto A, Tsuchiya N.,

    09/9/2024
    IGF2BP3 promotes mRNA degradation through internal m[7]G modification.

    IGF2BP3 promotes mRNA degradation through internal m(7)G modification.
    Liu C, Dou X, Zhao Y, Zhang L, Zhang L, Dai Q, Liu J, Wu T, Xiao Y, He C., Free PMC Article

    09/9/2024
    IGF2BP3 participates in the pathogenesis of recurrent spontaneous abortion by regulating ferroptosis.

    IGF2BP3 participates in the pathogenesis of recurrent spontaneous abortion by regulating ferroptosis.
    Dai F, Zhang Y, Deng Z, Zhang J, Wang R, Chen J, Yang D, Mao S, Liu H, Cheng Y, Hu M.

    09/9/2024
    Epigenetically associated IGF2BP3 upregulation promotes cell proliferation by regulating E2F1 expression in hepatocellular carcinoma.

    Epigenetically associated IGF2BP3 upregulation promotes cell proliferation by regulating E2F1 expression in hepatocellular carcinoma.
    Liu C, Zhuo Y, Yang X, Yang C, Shu M, Hou B, Hou J, Chen X, Wang L, Wu X., Free PMC Article

    08/8/2024
    circATAD2 mitigates CD8[+] T cells antitumor immune surveillance in breast cancer via IGF2BP3/m[6]A/PD-L1 manner.

    circATAD2 mitigates CD8(+) T cells antitumor immune surveillance in breast cancer via IGF2BP3/m(6)A/PD-L1 manner.
    Zhang Z, Huo W, Li J., Free PMC Article

    07/31/2024
    IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway.

    IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway.
    Ban Z, Li Z, Xing S, Ye Y., Free PMC Article

    06/12/2024
    Hsa_circ_0005320 affects cell proliferation and the cell cycle via the IGF2BP3/CDK2 axis in bladder cancer.

    Hsa_circ_0005320 affects cell proliferation and the cell cycle via the IGF2BP3/CDK2 axis in bladder cancer.
    Ji Q, Ma F, Zhang X, Liu Y, Wang P, Li M.

    06/12/2024
    N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT signal via de-SUMOylating HDAC2.

    N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT signal via de-SUMOylating HDAC2.
    Wen D, Xiao H, Gao Y, Zeng H, Deng J., Free PMC Article

    06/7/2024
    IGF2BP3 stabilizes SESN1 mRNA to mitigate oxidized low-density lipoprotein-induced oxidative stress and endothelial dysfunction in human umbilical vein endothelial cells by activating Nrf2 signaling.

    IGF2BP3 stabilizes SESN1 mRNA to mitigate oxidized low-density lipoprotein-induced oxidative stress and endothelial dysfunction in human umbilical vein endothelial cells by activating Nrf2 signaling.
    Gao F, Zhang B, Xiao C, Sun Z, Gao Y, Liu C, Dou X, Tong H, Wang R, Li P, Heng L.

    05/29/2024
    N6-methyladenosine methylation on FSCN1 mediated by METTL14/IGF2BP3 contributes to human papillomavirus type 16-infected cervical squamous cell carcinoma.

    N6-methyladenosine methylation on FSCN1 mediated by METTL14/IGF2BP3 contributes to human papillomavirus type 16-infected cervical squamous cell carcinoma.
    Tian Q, Huang J, Zhang Q, Zhao J.

    05/16/2024
    Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission.

    Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission.
    Yan J, Wang X, Fan Z, Xu Y, Zhang Y, Liu Y, Guo L, Liu D.

    05/7/2024
    m[6]A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia.

    m(6)A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia.
    Zhao Y, Zhou Y, Qian Y, Wei W, Lin X, Mao S, Sun J, Jin J., Free PMC Article

    04/8/2024
    Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript.

    Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript.
    Wang Z, Zhang H, Li F, Huang C., Free PMC Article

    03/26/2024
    NONO promotes gallbladder cancer cell proliferation by enhancing oncogenic RNA splicing of DLG1 through interaction with IGF2BP3/RBM14.

    NONO promotes gallbladder cancer cell proliferation by enhancing oncogenic RNA splicing of DLG1 through interaction with IGF2BP3/RBM14.
    Yang ZY, Zhao C, Liu SL, Pan LJ, Zhu YD, Zhao JW, Wang HK, Ye YY, Qiang J, Shi LQ, Mei JW, Xie Y, Gong W, Shu YJ, Dong P, Xiang SS.

    03/26/2024
    Depletion of the N[6]-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4.

    Depletion of the N(6)-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4.
    Deng L, Di Y, Chen C, Xia J, Lei B, Li N, Zhang Q., Free PMC Article

    03/14/2024
    The RNA m[6]A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.

    The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
    Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J., Free PMC Article

    03/12/2024
    Insulin-like growth factor 2 mRNA-binding protein 3 enhanced melanoma migration through regulation of AKT1 and RELA expression.

    Insulin-like growth factor 2 mRNA-binding protein 3 enhanced melanoma migration through regulation of AKT1 and RELA expression.
    Sheen YS, Syu YJ, Chang YC, Hsieh PH, Liao YH, Lin MH, Chen CY, Chu CY, Chu CY.

    03/1/2024
    IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD.

    IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD.
    Han C, Hu C, Liu T, Sun Y, Hu F, He Y, Zhang J, Chen J, Ding J, Fan J, Zhang X, Wang J, Qiao X, Jiang D, Yang K, Yang S., Free PMC Article

    02/21/2024
    Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.

    Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
    Wang J, Zheng F, Wang D, Yang Q., Free PMC Article

    02/21/2024
    Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs.

    Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs.
    Kaushik K, Kumar H, Mehta S, Palanichamy JK.

    02/13/2024
    Association of the m[6] A reader IGF2BP3 with tumor progression and brain-specific metastasis in breast cancer.

    Association of the m(6) A reader IGF2BP3 with tumor progression and brain-specific metastasis in breast cancer.
    Li Y, Cao J, Wang J, Wu W, Jiang L, Sun X.

    02/5/2024
    circRARS synergises with IGF2BP3 to regulate RNA methylation recognition to promote tumour progression in renal cell carcinoma.

    circRARS synergises with IGF2BP3 to regulate RNA methylation recognition to promote tumour progression in renal cell carcinoma.
    Liu Y, Chen K, Shou Y, Li S, Wang J, Zhang Q, Huang Z, Xu J, Li M, Liu D, Liang H, Yang H, Zhang X., Free PMC Article

    12/20/2023
    The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma.

    The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma.
    Chen B, Huang R, Xia T, Wang C, Xiao X, Lu S, Chen X, Ouyang Y, Deng X, Miao J, Zhao C, Wang L., Free PMC Article

    11/30/2023
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