| Targeting TXNIP in endothelial progenitors mitigates IL-8-induced neutrophil recruitment under metabolic stress. | Targeting TXNIP in endothelial progenitors mitigates IL-8-induced neutrophil recruitment under metabolic stress.
Jolibois J, Domingues A, El Hamaoui D, Awaida R, Berger-de-Gaillardo M, Guérin D, Smadja DM, Marquet-DeRougé P, Margaill I, Rossi E, Nivet-Antoine V., Free PMC Article | 09/6/2024 |
| TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway. | TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway.
Zhou W, Zhu C, Zhou F. | 09/3/2024 |
| Increased level of TXNIP and nuclear translocation of TXN is associated with end stage renal disease and development of multiplex renal tumours. | Increased level of TXNIP and nuclear translocation of TXN is associated with end stage renal disease and development of multiplex renal tumours.
Beothe T, Docs J, Kovacs G, Peterfi L., Free PMC Article | 08/16/2024 |
| Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study. | Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study.
Maeda K, Fujii R, Yamada H, Munetsuna E, Yamazaki M, Ando Y, Mizuno G, Ishikawa H, Ohashi K, Tsuboi Y, Hattori Y, Ishihara Y, Hamajima N, Hashimoto S, Suzuki K. | 07/9/2024 |
| A novel link between melatonin and circ_0005753/PTBP1/TXNIP regulatory network in the modulation of osteogenic potential in mesenchymal stem cells. | A novel link between melatonin and circ_0005753/PTBP1/TXNIP regulatory network in the modulation of osteogenic potential in mesenchymal stem cells.
Tu W, Zhu S, Li F, Xu C, Tu W, Chen Y. | 07/2/2024 |
| Serum carotenoid levels are positively associated with DNA methylation of thioredoxin-interacting protein. | Serum carotenoid levels are positively associated with DNA methylation of thioredoxin-interacting protein.
Maeda K, Yamada H, Munetsuna E, Fujii R, Yamazaki M, Ando Y, Mizuno G, Tsuboi Y, Ishikawa H, Ohashi K, Hashimoto S, Hamajima N, Suzuki K. | 06/27/2024 |
| TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease. | TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Du Y, Wu M, Song S, Bian Y, Shi Y., Free PMC Article | 05/3/2024 |
| Knockdown of TXNIP alleviates gestational diabetes mellitus by activating autophagy to regulate cell proliferation and apoptosis in high glucose-treated trophoblasts. | Knockdown of TXNIP alleviates gestational diabetes mellitus by activating autophagy to regulate cell proliferation and apoptosis in high glucose-treated trophoblasts.
Gu Y, Cao M, Chen Y, Li J, Hu L, Yang XJ. | 04/2/2024 |
| Amino acid deprivation induces TXNIP expression by NRF2 downregulation. | Amino acid deprivation induces TXNIP expression by NRF2 downregulation.
Ahn SH, Jang SK, Kim YJ, Kim G, Park KS, Park IC, Jin HO. | 03/20/2024 |
| Linc00657 promoted pyroptosis in THP-1-derived macrophages and exacerbated atherosclerosis via the miR-106b-5p/TXNIP/NLRP3 axis. | Linc00657 promoted pyroptosis in THP-1-derived macrophages and exacerbated atherosclerosis via the miR-106b-5p/TXNIP/NLRP3 axis.
Liang Y, Xu XD, Xu X, Cai YB, Zhu ZX, Zhu L, Ren K. | 03/20/2024 |
| KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling. | KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling.
Chen Y, Sun L, Liu H, Li J, Guo L, Wang Z., Free PMC Article | 02/28/2024 |
| METTL14 drives growth and metastasis of non-small cell lung cancer by regulating pri-miR-93-5p maturation and TXNIP expression. | METTL14 drives growth and metastasis of non-small cell lung cancer by regulating pri-miR-93-5p maturation and TXNIP expression.
Qian S, Liu J, Liao W, Wang F. | 02/7/2024 |
| Advanced glycation end products induce nucleus pulposus cell apoptosis by upregulating TXNIP via inhibiting glycolysis pathway in intervertebral disc degeneration. | Advanced glycation end products induce nucleus pulposus cell apoptosis by upregulating TXNIP via inhibiting glycolysis pathway in intervertebral disc degeneration.
Chen F, Sheng X, Sun H, Guo Q, Wang H, Wu L, Ni B, Yang J. | 01/26/2024 |
| TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production. | TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production.
Jung E, Baek EB, Hong EJ, Kang JH, Park S, Park S, Hong EJ, Cho YE, Ko JW, Won YS, Kwon HJ., Free PMC Article | 01/9/2024 |
| The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control. | The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control.
Deng J, Pan T, Liu Z, McCarthy C, Vicencio JM, Cao L, Alfano G, Suwaidan AA, Yin M, Beatson R, Ng T., Free PMC Article | 12/20/2023 |
| USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein. | USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein.
Shi S, Pan X, Chen M, Zhang L, Zhang S, Wang X, Shi S, Chen Z, Lin W, Jiang Y., Free PMC Article | 08/4/2023 |
| TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer's diseases. | TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer's diseases.
Kim J, Lim J, Yoo ID, Park S, Moon JS., Free PMC Article | 06/13/2023 |
| The Role of Txnip in Mediating Low-Magnesium-Driven Endothelial Dysfunction. | The Role of Txnip in Mediating Low-Magnesium-Driven Endothelial Dysfunction.
Locatelli L, Fedele G, Maier JA., Free PMC Article | 05/22/2023 |
| High TXNIP expression accelerates the migration and invasion of the GDM placenta trophoblast. | High TXNIP expression accelerates the migration and invasion of the GDM placenta trophoblast.
Sa R, Ma J, Yang J, Li DF, Du J, Jia JC, Li ZY, Huang N, A L, Sha R, Nai G, Hexig B, Meng JQ, Yu L., Free PMC Article | 04/12/2023 |
| TXNIP Exacerbates the Senescence and Aging-Related Dysfunction of beta Cells by Inducing Cell Cycle Arrest Through p38-p16/p21-CDK-Rb Pathway. | TXNIP Exacerbates the Senescence and Aging-Related Dysfunction of β Cells by Inducing Cell Cycle Arrest Through p38-p16/p21-CDK-Rb Pathway.
Li Y, Deng W, Wu J, He Q, Yang G, Luo X, Jia Y, Duan Y, Zhou L, Liu D. | 03/23/2023 |
| Various Expressions of PIK3C2A and TXNIP Genes and Their Potential Role as Independent Risk Factors for Chronic Stable Angina and Acute Coronary Syndrome. | Various Expressions of PIK3C2A and TXNIP Genes and Their Potential Role as Independent Risk Factors for Chronic Stable Angina and Acute Coronary Syndrome.
Soliman SE, Abouelenin MAH, Samy NI, Omar MM, Alrefai AA., Free PMC Article | 03/1/2023 |
| Physiological and Pathophysiological Roles of Thioredoxin Interacting Protein: A Perspective on Redox Inflammation and Metabolism. | Physiological and Pathophysiological Roles of Thioredoxin Interacting Protein: A Perspective on Redox Inflammation and Metabolism.
Dagdeviren S, Lee RT, Wu N., Free PMC Article | 02/22/2023 |
| Novel lncRNA-prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease. | Novel lncRNA-prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease.
Song Y, Guo F, Zhao YY, Ma XJ, Wu LN, Yu JF, Ji HF, Shao MW, Huang FJ, Zhao L, Fan XJ, Xu YN, Wang QZ, Qin GJ., Free PMC Article | 02/11/2023 |
| TXNIP DNA methylation is associated with glycemic control over 28 years in type 1 diabetes: findings from the Pittsburgh Epidemiology of Diabetes Complications (EDC) study. | TXNIP DNA methylation is associated with glycemic control over 28 years in type 1 diabetes: findings from the Pittsburgh Epidemiology of Diabetes Complications (EDC) study.
Miller RG, Mychaleckyj JC, Onengut-Gumuscu S, Orchard TJ, Costacou T., Free PMC Article | 01/14/2023 |
| TXNIP Suppresses the Osteochondrogenic Switch of Vascular Smooth Muscle Cells in Atherosclerosis. | TXNIP Suppresses the Osteochondrogenic Switch of Vascular Smooth Muscle Cells in Atherosclerosis.
Woo SH, Kyung D, Lee SH, Park KS, Kim M, Kim K, Kwon HJ, Won YS, Choi I, Park YJ, Go DM, Oh JS, Yoon WK, Paik SS, Kim JH, Kim YH, Choi JH, Kim DY., Free PMC Article | 01/14/2023 |