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    ARID3B AT-rich interaction domain 3B [ Homo sapiens (human) ]

    Gene ID: 10620, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Distinct and overlapping roles of ARID3A and ARID3B in regulating E2Fdependent transcription via direct binding to E2F target genes.

    Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes.
    Saadat KASM, Lestari W, Pratama E, Ma T, Iseki S, Tatsumi M, Ikeda MA.

    11/6/2021
    Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer.

    Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer.
    Liao TT, Lin CC, Jiang JK, Yang SH, Teng HW, Yang MH., Free PMC Article

    05/22/2021
    Genotype-Based Gene Expression in Colon Tissue-Prediction Accuracy and Relationship with the Prognosis of Colorectal Cancer Patients.

    Genotype-Based Gene Expression in Colon Tissue-Prediction Accuracy and Relationship with the Prognosis of Colorectal Cancer Patients.
    Deutelmoser H, Lorenzo Bermejo J, Benner A, Weigl K, Park HA, Haffa M, Herpel E, Schneider M, Ulrich CM, Hoffmeister M, Chang-Claude J, Brenner H, Scherer D., Free PMC Article

    03/28/2021
    Knockout of LIN28A and LIN28B in ACH-3P cells not only significantly increased amounts of let-7 miRNAs but also led to significant reduction in ARID3B-complex proteins, potentially because of increased targeting by let-7 miRNAs.

    LIN28-let-7 axis regulates genes in immortalized human trophoblast cells by targeting the ARID3B-complex.
    Ali A, Anthony RV, Bouma GJ, Winger QA., Free PMC Article

    05/30/2020
    Study provides a comprehensive list of genes and pathways regulated by ARID3A and ARID3B in ovarian cancer cells.

    ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells.
    Dausinas P, Pulakanti K, Rao S, Cole JM, Dahl R, Cowden Dahl KD., Free PMC Article

    05/2/2020
    A novel cellular protein (AT-rich interacting domain protein 3B [ARID3B]) that we show is able to temper lytic reactivation.

    ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.
    Wood JJ, Boyne JR, Paulus C, Jackson BR, Nevels MM, Whitehouse A, Hughes DJ., Free PMC Article

    05/13/2017
    Data indicate that the most prominent proteins associating with Gab2 are PTPN11, PIK3R1 and ARID3B.

    Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes.
    Osinalde N, Sánchez-Quiles V, Blagoev B, Kratchmarova I., Free PMC Article

    02/4/2017
    Although ARID3B and ARID3A share overlapping functions, ARID3B play a key role in the expression of pro-apoptotic p53-target genes and apoptosis.

    Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis.
    Pratama E, Tian X, Lestari W, Iseki S, Ichwan SJ, Ikeda MA.

    03/12/2016
    ARID3B boosts production CD133+ tumor stem cells and increases ovarian cancer progression in vivo.

    ARID3B increases ovarian tumor burden and is associated with a cancer stem cell gene signature.
    Roy L, Samyesudhas SJ, Carrasco M, Li J, Joseph S, Dahl R, Cowden Dahl KD., Free PMC Article

    06/27/2015
    Data report a positive correlation between ER positivity and nuclear ARID3B expression in primary breast cancers, along with a negative correlation with the ERBB2 status.

    ARID3B expression in primary breast cancers and breast cancer-derived cell lines.
    Oguz Erdogan AS, Ozdemirler N, Oyken M, Alper M, Erson-Bensan AE.

    05/16/2015
    The different patterns of ARID3B in normal tissues translate into different roles for ARID3B in carcinomas.

    Differential expression of ARID3B in normal adult tissue and carcinomas.
    Samyesudhas SJ, Roy L, Cowden Dahl KD.

    07/5/2014
    Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn.

    Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn.
    Kobayashi K, Jakt LM, Nishikawa SI., Free PMC Article

    08/10/2013
    ARID3B Fl induces death receptor mediated apoptosis while the novel splice form ARID3B Sh does not induce cell death

    ARID3B induces tumor necrosis factor alpha mediated apoptosis while a novel ARID3B splice form does not induce cell death.
    Joseph S, Deneke VE, Cowden Dahl KD., Free PMC Article

    01/26/2013
    Among possible numerous targets of miR-125b, we showed ARID3B (AT-rich interactive domain 3B) to be a novel target with roles in cell motility in breast cancer cells.

    miR-125b targets ARID3B in breast cancer cells.
    Akhavantabasi S, Sapmaz A, Tuna S, Erson-Bensan AE.

    05/26/2012
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    We identify AT-rich interactive domain 3B (ARID3B) as a target of miR-125a and demonstrate that ARID3B is overexpressed in human ovarian cancer

    The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells.
    Cowden Dahl KD, Dahl R, Kruichak JN, Hudson LG., Free PMC Article

    01/21/2010
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