| Advances in the antitumor mechanisms of tripartite motif-containing protein 3. | Advances in the antitumor mechanisms of tripartite motif-containing protein 3.
Teng W, Ling Y, Liu Z, Jiang L, Fu G, Zhou X, Long N, Liu J, Chu L., Free PMC Article | 02/28/2024 |
| TRIM3 facilitates ferroptosis in non-small cell lung cancer through promoting SLC7A11/xCT K11-linked ubiquitination and degradation. | TRIM3 facilitates ferroptosis in non-small cell lung cancer through promoting SLC7A11/xCT K11-linked ubiquitination and degradation.
Wang Z, Shen N, Wang Z, Yu L, Yang S, Wang Y, Liu Y, Han G, Zhang Q., | 01/12/2024 |
| Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity. | Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.
Esposito D, Dudley-Fraser J, Garza-Garcia A, Rittinger K., Free PMC Article | 12/24/2022 |
| TRIM3 Inhibits H2O2-Induced Apoptosis in Human Lens Epithelial Cells by Decreasing p53 via Ubiquitination. | TRIM3 Inhibits H(2)O(2)-Induced Apoptosis in Human Lens Epithelial Cells by Decreasing p53 via Ubiquitination.
Deng Y, Shi Y, Wen C. | 06/11/2022 |
| TRIM3 facilitates estrogen signaling and modulates breast cancer cell progression. | TRIM3 facilitates estrogen signaling and modulates breast cancer cell progression.
Zhuang T, Wang B, Tan X, Wu L, Li X, Li Z, Cai Y, Fan R, Yang X, Zhang C, Xia Y, Niu Z, Liu B, Cao Q, Ding Y, Zhou Z, Huang Q, Yang H., Free PMC Article | 04/23/2022 |
| Decreased expression of TRIM3 gene predicts a poor prognosis in gastric cancer. | Decreased expression of TRIM3 gene predicts a poor prognosis in gastric cancer.
Farhadi J, Goshayeshi L, Motavalizadehkakhky A, Mehrzad J, Mehrad-Majd H. | 04/2/2022 |
| TRIM3 attenuates apoptosis in Parkinson's disease via activating PI3K/AKT signal pathway. | TRIM3 attenuates apoptosis in Parkinson's disease via activating PI3K/AKT signal pathway.
Dong W, Luo B, Qiu C, Jiang X, Shen B, Zhang L, Liu W, Zhang W., Free PMC Article | 05/15/2021 |
| miR-454-3p promotes proliferation and induces apoptosis in human cervical cancer cells by targeting TRIM3. | miR-454-3p promotes proliferation and induces apoptosis in human cervical cancer cells by targeting TRIM3.
Song Y, Guo Q, Gao S, Hua K. | 07/11/2020 |
| Foxo3a exerted inhibitory effects on LPS-induced proliferation and inflammation through increasing TRIM3 transcription. | Forkhead box o3a suppresses lipopolysaccharide-stimulated proliferation and inflammation in fibroblast-like synoviocytes through regulating tripartite motif-containing protein 3.
Wang M, Wu J, Zhou E, Chang X, Gan J, Cheng T. | 05/30/2020 |
| after silencing or overexpressing TRIM31 expression, the proliferation, invasion and migration of glioma cells could be downregulated or upregulated through Akt signaling pathway | TRIM31 promotes proliferation, invasion and migration of glioma cells through Akt signaling pathway.
Shi G, Lv C, Yang Z, Qin T, Sun L, Pan P, Wang D. | 10/12/2019 |
| Exosomal TRIM3 may serve as a biomarker for gastric cancer diagnosis. | Exosomal TRIM3 is a novel marker and therapy target for gastric cancer.
Fu H, Yang H, Zhang X, Wang B, Mao J, Li X, Wang M, Zhang B, Sun Z, Qian H, Xu W., Free PMC Article | 07/13/2019 |
| Tripartite motif-containing 3 (TRIM3) directly interacts with and induces E3 ligase-dependent proteasomal turnover of importin alpha3 and alpha-Actinin-4 (ACTN4). | Targeting TRIM3 deletion-induced tumor-associated lymphangiogenesis prohibits lymphatic metastasis in esophageal squamous cell carcinoma.
Zhu J, Wu G, Ke Z, Cao L, Tang M, Li Z, Li Q, Zhou J, Tan Z, Song L, Li J. | 05/4/2019 |
| TRIM3 plays a tumor-suppressing role in the regulation of liver cancer development by reducing cell proliferation through cell cycle arrest at the G0/G1 phase. | Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer.
Huang XQ, Zhang XF, Xia JH, Chao J, Pan QZ, Zhao JJ, Zhou ZQ, Chen CL, Tang Y, Weng DS, Zhang JH, Xia JC., Free PMC Article | 05/26/2018 |
| The results of quantitative real-time RT-PCR and western blotting showed that the TRIM3 expression was very low in five cervical cancer cell lines. The TRIM3 overexpression weakened cell viability, and promote apoptosis of C-33A and SiHa cells in vitro, and inhibit tumor growth in vivo, which suggested that TRIM3 could reduce proliferation of cervical cancer cells. | Tripartite motif-containing protein 3 plays a role of tumor inhibitor in cervical cancer.
Song Y, Guo Q, Gao S, Hua K. | 05/5/2018 |
| TRIM3 exerted an anti-proliferation role in rheumatoid arthritis fibroblast-like synoviocytes via p38 signaling pathway. | The tripartite motif-containing protein 3 on the proliferation and cytokine secretion of rheumatoid arthritis fibroblast-like synoviocytes.
Wang M, Wu J, Guo Y, Chang X, Cheng T., Free PMC Article | 05/27/2017 |
| results support a novel role for Brat/TRIM3 in maintaining stem cell equilibrium and suppressing tumor growth by regulating NICD nuclear transport | Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport.
Mukherjee S, Tucker-Burden C, Zhang C, Moberg K, Read R, Hadjipanayis C, Brat DJ., Free PMC Article | 03/4/2017 |
| TRIM3 functions as a tumour suppressor in CRC progression. This tumour-suppressive function is exerted partially through regulation of p53 protein. | Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development.
Piao MY, Cao HL, He NN, Xu MQ, Dong WX, Wang WQ, Wang BM, Zhou B. | 11/5/2016 |
| Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases. | TRIM-NHL proteins in development and disease.
Tocchini C, Ciosk R. | 10/1/2016 |
| TRIM3 may play a significant role in hepatocellular carcinoma progression.TRIM3 is downregulated in hepatocellular carcinoma at both the mRNA and protein levels and that low TRIM3 expression is correlated with an unfavorable prognosis. | Decreased expression of TRIM3 is associated with poor prognosis in patients with primary hepatocellular carcinoma.
Chao J, Zhang XF, Pan QZ, Zhao JJ, Jiang SS, Wang Y, Zhang JH, Xia JC. | 05/16/2015 |
| TRIM3 acts as a tumor suppressor in GBM by restoring asymmetric cell division. | Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma.
Chen G, Kong J, Tucker-Burden C, Anand M, Rong Y, Rahman F, Moreno CS, Van Meir EG, Hadjipanayis CG, Brat DJ., Free PMC Article | 12/20/2014 |
| Data indicate TRIM3 and p21 interact in cells. | TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).
Liu Y, Raheja R, Yeh N, Ciznadija D, Pedraza AM, Ozawa T, Hukkelhoven E, Erdjument-Bromage H, Tempst P, Gauthier NP, Brennan C, Holland EC, Koff A., Free PMC Article | 03/15/2014 |
| TRIM63 is a candidate for genes mediating the glucocorticoid-induced promotion of osteoblastic differentiation. | Glucocorticoid-induced gene tripartite motif-containing 63 (TRIM63) promotes differentiation of osteoblastic cells.
Azuma K, Urano T, Ouchi Y, Inoue S. | 09/13/2010 |
| brain-expressed RING finger protein (BERP) is a gene whose expression is up-regulated in a p53-dependent manner | Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors.
Cheung CC, Yang C, Berger T, Zaugg K, Reilly P, Elia AJ, Wakeham A, You-Ten A, Chang N, Li L, Wan Q, Mak TW., Free PMC Article | 08/16/2010 |
| Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene. | Loss of heterozygosity of TRIM3 in malignant gliomas.
Boulay JL, Stiefel U, Taylor E, Dolder B, Merlo A, Hirth F., Free PMC Article | 01/21/2010 |
| Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. | Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW. | 01/28/2009 |