| Homozygous variants in AKAP3 induce asthenoteratozoospermia and male infertility. | Homozygous variants in AKAP3 induce asthenoteratozoospermia and male infertility.
Liu C, Shen Y, Tang S, Wang J, Zhou Y, Tian S, Wu H, Cong J, He X, Jin L, Cao Y, Yang Y, Zhang F. | 01/28/2023 |
| The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signaling. | The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signaling.
Zhan CH, Ding DS, Zhang W, Wang HL, Mao ZY, Liu GJ., Free PMC Article | 07/30/2022 |
| Structural modeling of human AKAP3 protein and in silico analysis of single nucleotide polymorphisms associated with sperm motility. | Structural modeling of human AKAP3 protein and in silico analysis of single nucleotide polymorphisms associated with sperm motility.
Rafaee A, Kashani-Amin E, Meybodi AM, Ebrahim-Habibi A, Sabbaghian M., Free PMC Article | 04/23/2022 |
| Protein Kinase A (PRKA) Activity Is Regulated by the Proteasome at the Onset of Human Sperm Capacitation. | Protein Kinase A (PRKA) Activity Is Regulated by the Proteasome at the Onset of Human Sperm Capacitation.
Zapata-Carmona H, Barón L, Kong M, Morales P., Free PMC Article | 01/8/2022 |
| The present study revealed that one of the major rHuOVGP1-enhanced pY proteins could be AKAP3 of the FS and that rHuOVGP1 is capable of binding to human ZP and its presence in the medium results in an increase in sperm-zona binding. Supplement of rHuOVGP1 in in vitro fertilization media could be beneficial for enhancement of the fertilizing ability of human sperm. | Human OVGP1 enhances tyrosine phosphorylation of proteins in the fibrous sheath involving AKAP3 and increases sperm-zona binding.
Zhao Y, Kan FWK., Free PMC Article | 12/14/2019 |
| AKAP3 correlates with triple negative status and disease free survival in breast cancer. | AKAP3 correlates with triple negative status and disease free survival in breast cancer.
Esmaeili R, Majidzadeh-A K, Farahmand L, Ghasemi M, Salehi M, Khoshdel AR., Free PMC Article | 07/2/2016 |
| study reports the isolation of AKAP3 and CTp11 Cancer/testis antigens from hepatocellular carcinoma patient sera | Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma.
Song MH, Choi KU, Shin DH, Lee CH, Lee SY. | 03/16/2013 |
| CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath. | CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.
Li YF, He W, Mandal A, Kim YH, Digilio L, Klotz K, Flickinger CJ, Herr JC, Herr JC., Free PMC Article | 07/16/2011 |
| AKAP3 is a novel target for protein S-nitrosylation in spermatozoa. | Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide?
Lefièvre L, Chen Y, Conner SJ, Scott JL, Publicover SJ, Ford WC, Barratt CL., Free PMC Article | 01/21/2010 |
| AKAP-3 demonstrates tumor-restricted expression and appears to be associated with worse overall survival. | A-kinase anchoring protein 3 messenger RNA expression correlates with poor prognosis in epithelial ovarian cancer.
Sharma S, Qian F, Keitz B, Driscoll D, Scanlan MJ, Skipper J, Rodabaugh K, Lele S, Old LJ, Odunsi K. | 01/21/2010 |
| evidence of tyrosine phosphorylation during sperm capacitation | Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.
Ficarro S, Chertihin O, Westbrook VA, White F, Jayes F, Kalab P, Marto JA, Shabanowitz J, Herr JC, Hunt DF, Visconti PE. | 01/21/2010 |
| In Cox multivariate analysis, AKAP3 mRNA expression was found to be a significant predictor of both overall and progression-free survival in patients with poorly differentiated tumors. | A-kinase anchoring protein 3 messenger RNA expression in ovarian cancer and its implication on prognosis.
Hasegawa K, Ono T, Matsushita H, Shimono M, Noguchi Y, Mizutani Y, Kodama J, Kudo T, Nakayama E. | 01/21/2010 |