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    CEBPA CCAAT enhancer binding protein alpha [ Homo sapiens (human) ]

    Gene ID: 1050, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Nemo-like kinase blocks myeloid differentiation by targeting tumor suppressor C/EBPalpha in AML.

    Nemo-like kinase blocks myeloid differentiation by targeting tumor suppressor C/EBPα in AML.
    Singh AK, Thacker G, Upadhyay V, Mishra M, Sharma A, Sethi A, Chowdhury S, Siddiqui S, Verma SP, Pandey A, Bhatt MLB, Trivedi AK.

    10/25/2024
    Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids.

    Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids.
    Gu S, Huang X, Luo S, Liu Y, Khoong Y, Liang H, Tu L, Xu R, Yang E, Zhao Y, Yao M, Zan T.,

    10/23/2024
    miR-942-5p Regulates Proliferation, Invasion and EMT of Trophoblast Cells in Gestational Diabetes by Targeting the CEBPA.

    miR-942-5p Regulates Proliferation, Invasion and EMT of Trophoblast Cells in Gestational Diabetes by Targeting the CEBPA.
    Chu Q, Zhong X, Lu Y, Xu Y.

    10/1/2024
    Erythropoietin enhances iron bioavailability in HepG2 cells by downregulating hepcidin through mTOR, C/EBPalpha and HIF-1alpha.

    Erythropoietin enhances iron bioavailability in HepG2 cells by downregulating hepcidin through mTOR, C/EBPα and HIF-1α.
    Maltaneri RE, Chamorro ME, Gionco SE, Nesse AB, Vittori DC.

    09/9/2024
    Ring finger protein 138 inhibits transcription factor C/EBPalpha protein turnover leading to differentiation arrest in acute myeloid leukemia.

    Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia.
    Singh AK, Upadhyay V, Sethi A, Chowdhury S, Mishra S, Verma SP, Bhatt MLB, Trivedi AK.

    06/27/2024
    CEBPA double mutations associated with ABO antigen weakness in hematologic diseases.

    CEBPA double mutations associated with ABO antigen weakness in hematologic diseases.
    Choi SJ, Kim HK, Suh EJ, Kwon SS, Shin S, Lee ST, Kim S., Free PMC Article

    03/19/2024
    Clinical features and management of germline CEBPA-mutated carriers.

    Clinical features and management of germline CEBPA-mutated carriers.
    Pan L, Li Y, Gao H, Lai X, Cai Y, Chen Z, Li X, Wang SY.

    03/15/2024
    C/EBPalpha-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription.

    C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription.
    Du M, Wang M, Liu M, Fu S, Lin Y, Huo Y, Yu J, Yu X, Wang C, Xiao H, Wang L., Free PMC Article

    03/14/2024
    C/EBPalpha mediates the maturation and antitumor functions of macrophages in human hepatocellular carcinoma.

    C/EBPα mediates the maturation and antitumor functions of macrophages in human hepatocellular carcinoma.
    Wang Y, Li Z, Chen W, Wang J, Huang Z, Yu XJ, Zhang YJ, Zheng L, Xu J.

    03/5/2024
    A blastic plasmacytoid dendritic cell neoplasm-like immunophenotype is negatively associated with CEBPA bZIP mutation and predicts unfavorable prognosis in acute myeloid leukemia.

    A blastic plasmacytoid dendritic cell neoplasm-like immunophenotype is negatively associated with CEBPA bZIP mutation and predicts unfavorable prognosis in acute myeloid leukemia.
    Song J, Li W, Bai Y, Zhou P, Niu J, Niu X, Liu Y, Liu X, Drokow EK, Sun K, Zhou H.

    02/1/2024
    The Role of DNMT1 and C/EBPalpha in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.

    The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.
    Zhu YN, Pan F, Gan XW, Liu Y, Wang WS, Sun K.

    01/4/2024
    AML with CEBPA mutations: A comparison of ICC and WHO-HAEM5 criteria in patients with 20% or more blasts.

    AML with CEBPA mutations: A comparison of ICC and WHO-HAEM5 criteria in patients with 20% or more blasts.
    Zhao D, Zhou Q, Zarif M, Eladl E, Wei C, Atenafu EG, Schuh A, Tierens A, Yeung YWT, Minden MD, Chang H.

    11/8/2023
    Homodimer-mediated phosphorylation of C/EBPalpha-p42 S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation.

    Homodimer-mediated phosphorylation of C/EBPα-p42 S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation.
    Wang D, Sun T, Xia Y, Zhao Z, Sheng X, Li S, Ma Y, Li M, Su X, Zhang F, Li P, Ma D, Ye J, Lu F, Ji C., Free PMC Article

    11/3/2023
    Immunophenotype distinctions of CEBPA mutation subtypes in acute myeloid leukemia.

    Immunophenotype distinctions of CEBPA mutation subtypes in acute myeloid leukemia.
    Liu Q, Qi L, Yang M, Zhang X, Li F, Wei H, Wang J.

    09/15/2023
    C/ebpalpha represses the oncogenic Runx3-Myc axis in p53-deficient osteosarcoma development.

    C/ebpα represses the oncogenic Runx3-Myc axis in p53-deficient osteosarcoma development.
    Omori K, Otani S, Date Y, Ueno T, Ito T, Umeda M, Ito K.

    08/16/2023
    C/EBPalpha Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia.

    C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia.
    Sabatier M, Birsen R, Lauture L, Mouche S, Angelino P, Dehairs J, Goupille L, Boussaid I, Heiblig M, Boet E, Sahal A, Saland E, Santos JC, Armengol M, Fernández-Serrano M, Farge T, Cognet G, Simonetta F, Pignon C, Graffeuil A, Mazzotti C, Avet-Loiseau H, Delos O, Bertrand-Michel J, Chedru A, Dembitz V, Gallipoli P, Anstee NS, Loo S, Wei AH, Carroll M, Goubard A, Castellano R, Collette Y, Vergez F, Mansat-De Mas V, Bertoli S, Tavitian S, Picard M, Récher C, Bourges-Abella N, Granat F, Kosmider O, Sujobert P, Colsch B, Joffre C, Stuani L, Swinnen JV, Guillou H, Roué G, Hakim N, Dejean AS, Tsantoulis P, Larrue C, Bouscary D, Tamburini J, Sarry JE.

    07/23/2023
    Carm1-arginine methylation of the transcription factor C/EBPalpha regulates transdifferentiation velocity.

    Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
    Torcal Garcia G, Kowenz-Leutz E, Tian TV, Klonizakis A, Lerner J, De Andres-Aguayo L, Sapozhnikova V, Berenguer C, Carmona MP, Casadesus MV, Bulteau R, Francesconi M, Peiro S, Mertins P, Zaret K, Leutz A, Graf T., Free PMC Article

    07/5/2023
    Hereditary acute myeloid leukemia associated with C-terminal CEBPA germline variants.

    Hereditary acute myeloid leukemia associated with C-terminal CEBPA germline variants.
    Harrigan AM, Trottier AM.

    06/22/2023
    The molecular mechanism of gamma-aminobutyric acid against AD: the role of CEBPalpha/circAPLP2/miR-671-5p in regulating CNTN1/2 expression.

    The molecular mechanism of γ-aminobutyric acid against AD: the role of CEBPα/circAPLP2/miR-671-5p in regulating CNTN1/2 expression.
    Meng N, Pan P, Hu S, Miao C, Hu Y, Wang F, Zhang J, An L.

    02/27/2023
    [Restratifying the prognosis of acute myeloid leukemia patients with CEBPA double mutations based on CSF3R mutations and measurable residual disease].

    [Restratifying the prognosis of acute myeloid leukemia patients with CEBPA double mutations based on CSF3R mutations and measurable residual disease].
    Su L, Tan YH, Lin H, Han W, Yang YP, Liu XL, Sun JN, Liu QJ, Gao SJ., Free PMC Article

    02/4/2023
    Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.

    Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.
    Adamo A, Chin P, Keane P, Assi SA, Potluri S, Kellaway SG, Coleman D, Ames L, Ptasinska A, Delwel HR, Cockerill PN, Bonifer C., Free PMC Article

    02/4/2023
    A clinicopathological experience in acute myeloid leukemia: Effects of clinical data and status of FLT3, CEBPA and NPM1 on prognosis.

    A clinicopathological experience in acute myeloid leukemia: Effects of clinical data and status of FLT3, CEBPA and NPM1 on prognosis.
    Yener E, Ozcan K, Öngören Ş, Salihoğlu A, Demiröz AS, Akı H.

    08/6/2022
    Companion gene mutations and their clinical significance in AML with double or single mutant CEBPA.

    Companion gene mutations and their clinical significance in AML with double or single mutant CEBPA.
    He J, Liu J, Shen H, Wang Z, Cao L, Wu P, Chao H, Lu X, Jia Z, Chen M, Cai X.

    07/2/2022
    Acute myeloid leukemia due to germline CEBPA mutation in a Syrian family.

    Acute myeloid leukemia due to germline CEBPA mutation in a Syrian family.
    Wafa A, Ali B, Moassass F, Kheder M, Aljapawe A, Al-Halabi B, Mrasek K, Liehr T, Al-Achkar W., Free PMC Article

    06/18/2022
    The prognostic factors in acute myeloid leukaemia with double-mutated CCAAT/enhancer-binding protein alpha (CEBPAdm).

    The prognostic factors in acute myeloid leukaemia with double-mutated CCAAT/enhancer-binding protein alpha (CEBPAdm).
    Wei H, Zhou C, Liu B, Lin D, Li Y, Wei S, Gong B, Zhang G, Liu K, Gong X, Fang Q, Liu Y, Qiu S, Gu R, Song Z, Chen J, Yang M, Zhang J, Jin J, Wang Y, Mi Y, Wang J.

    05/14/2022
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