| DDX5 promotes esophageal squamous cell carcinoma growth through sustaining VAV3 mRNA stability. | DDX5 promotes esophageal squamous cell carcinoma growth through sustaining VAV3 mRNA stability.
Shi Y, Wang J, Yuan Q, Chen Y, Zhao M, Li X, Wang Z, Zhou H, Zhu F, Wei B, Jiang Y, Zhao J, Qiao Y, Dong Z, Liu K. | 11/7/2024 |
| Serum exosome-derived miR-146a-3p promotes macrophage M2 polarization in allergic rhinitis by targeting VAV3 via PI3K/AKT/mTOR pathway. | Serum exosome-derived miR-146a-3p promotes macrophage M2 polarization in allergic rhinitis by targeting VAV3 via PI3K/AKT/mTOR pathway.
Xia C, Zhu K, Zhang Y, Chen J, Yu C, Gao T, Zheng G. | 11/2/2023 |
| VAV3 in human cancers: Mechanism and clinical implication. | VAV3 in human cancers: Mechanism and clinical implication.
Al-Hawary SIS, Alsalamy A, Gupta R, Alsaab HO, Hjazi A, Edilboyev U, Ramadan MF, Hussien BM, Ahmed M, Hosseini-Fard SR. | 08/17/2023 |
| Rs7537605 polymorphism in VAV3 gene and rs28665122 polymorphism in SEPS gene are not associated with Hashimoto's thyroiditis in North-East Algerian population. | Rs7537605 polymorphism in VAV3 gene and rs28665122 polymorphism in SEPS gene are not associated with Hashimoto's thyroiditis in North-East Algerian population.
Kherrour W, Benbia S, Hambaba L, Kaličanin D., Free PMC Article | 05/4/2023 |
| CARD9, VAV3, and infection risk in IgA nephropathy. | CARD9, VAV3, and infection risk in IgA nephropathy.
Gleeson PJ, Sokol H, Monteiro RC. | 04/26/2023 |
| VAV3 regulates glioblastoma cell proliferation, migration, invasion and cancer stem-like cell self-renewal. | VAV3 regulates glioblastoma cell proliferation, migration, invasion and cancer stem‑like cell self‑renewal.
Miao R, Huang D, Zhao K, Li Y, Zhang X, Cheng Y, Guo N., Free PMC Article | 03/27/2023 |
| Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium. | Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium.
Badaoui M, Sobolewski C, Luscher A, Bacchetta M, Köhler T, van Delden C, Foti M, Chanson M., Free PMC Article | 02/26/2023 |
| Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. | Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis.
Nayak RC, Chang KH, Singh AK, Kotliar M, Desai M, Wellendorf AM, Wunderlich M, Bartram J, Mizukawa B, Cuadrado M, Dexheimer P, Barski A, Bustelo XR, Nassar NN, Cancelas JA., Free PMC Article | 06/11/2022 |
| The effect of VAV3 polymorphisms on thyroid cancer. | The effect of VAV3 polymorphisms on thyroid cancer.
Ren W, Xu C, Wang S, Li H, Dai H, Yang F, Shao Y, Bai Y. | 03/26/2022 |
| Vav3 Mediates Pseudomonas aeruginosa Adhesion to the Cystic Fibrosis Airway Epithelium. | Vav3 Mediates Pseudomonas aeruginosa Adhesion to the Cystic Fibrosis Airway Epithelium.
Badaoui M, Zoso A, Idris T, Bacchetta M, Simonin J, Lemeille S, Wehrle-Haller B, Chanson M. | 05/1/2021 |
| VAV3 rs7528153 and VAV3-AS1 rs1185222 polymorphisms are associated with an increased risk of developing hypertension. | VAV3 rs7528153 and VAV3-AS1 rs1185222 polymorphisms are associated with an increased risk of developing hypertension.
Miramontes-González JP, Usategui-Martín R, Martín-Vallejo J, Ziegler M, de Isla LL, O Connor D, González-Sarmiento R. | 02/20/2021 |
| Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression. | Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression.
Chen Z, Chen X, Lu B, Gu Y, Chen Q, Lei T, Nie F, Gu J, Huang J, Wei C, Sun M, Wang Z., Free PMC Article | 02/2/2021 |
| The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration. | The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration.
Ojala VK, Knittle AM, Kirjalainen P, Merilahti JAM, Kortesoja M, Tvorogov D, Vaparanta K, Lin S, Kast J, Pulliainen AT, Kurppa KJ, Elenius K., Free PMC Article | 01/23/2021 |
| Inactivation of Vav3 in vivo resulted in increased vascular leakage, highlighting its function as a key regulator of barrier stability. | Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.
Hilfenhaus G, Nguyen DP, Freshman J, Prajapati D, Ma F, Song D, Ziyad S, Cuadrado M, Pellegrini M, Bustelo XR, Iruela-Arispe ML., Free PMC Article | 07/20/2019 |
| Vav3 in peripheral blood may serve as a biomarker for gastric cancer, and to predict the lymphatic metastasis in gastric cancer. | The clinical value of Vav3 in peripheral blood for predicting lymphatic metastasis of gastric cancer.
Tan B, Li Y, Wang C, Tan M, Fan L, Zhao Q, Wang D, Jia N. | 06/29/2019 |
| The N-terminal truncated Vav3.1 may be decisively involved in mechanisms causing genuine multi-drug resistance. | Truncated isoform Vav3.1 is highly expressed in ovarian cancer stem cells and clinically relevant in predicting prognosis and platinum-response.
Reimer D, Boesch M, Wolf D, Marth C, Sopper S, Hatina J, Altevogt P, Parson W, Hackl H, Zeimet AG. | 11/3/2018 |
| VAV3 polymorphisms associate with cardiovascular risk factors and target organ damage. | Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors.
Perretta-Tejedor N, Fernández-Mateos J, García-Ortiz L, Gómez-Marcos MA, Recio-Rodríguez JI, Agudo-Conde C, Rodriguez-Sánchez E, Morales AI, López-Hernández FJ, López-Novoa JM, González-Sarmiento R, Martínez-Salgado C., Free PMC Article | 10/27/2018 |
| High VAV3 variant expression is associated with endometrial cancer. | Evaluation of Vav3.1 as prognostic marker in endometrial cancer.
Boesch M, Sopper S, Marth C, Fiegl H, Wiedemair A, Rössler J, Hatina J, Wolf D, Reimer D, Zeimet AG., Free PMC Article | 10/6/2018 |
| Results identified the diffuse B-cell lymphoma homology (DH) domain of Vav3 that interacts with the N-terminal region of AR-V7 (splice variants) and increases its expression in castration-resistant prostate cancer (CRPC). This interaction disrupted AR-V7 interaction with other AR coactivators like Src1 and Vav2. | Targeting AR Variant-Coactivator Interactions to Exploit Prostate Cancer Vulnerabilities.
Magani F, Peacock SO, Rice MA, Martinez MJ, Greene AM, Magani PS, Lyles R, Weitz JR, Burnstein KL., Free PMC Article | 06/16/2018 |
| We then explore the consequences of phorbol ester binding to a modified Vav3 in which the C1 domain has been altered to allow phorbol ester binding. We find both disruption of the guanyl nucleotide exchange activity of the modified Vav 3 as well as a shift in localization to the membrane upon phorbol ester treatment. | The C1 domain of Vav3, a novel potential therapeutic target.
Kelsey JS, Géczy T, Kaler CJ, Blumberg PM., Free PMC Article | 06/16/2018 |
| Overexpression of Vav3 is an independent risk factor for prognosis of gastric cancer, and can be used as a prognostic indicator. | Expression of Vav3 protein and its prognostic value in patients with gastric cancer.
Tan B, Li Y, Shi X, Fan L, Zhao Q, Liu Y, Tan M, Liu Q, Jia N. | 04/21/2018 |
| Vav3 is a novel TRAF6 interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex. | Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.
Yu J, Yun H, Shin B, Kim Y, Park ES, Choi S, Yu J, Amarasekara DS, Kim S, Inoue J, Walsh MC, Choi Y, Takami M, Rho J., Free PMC Article | 05/20/2017 |
| this study shows that the anti-tumor effects of astragaloside IV are mediated by the downregulation of Vav3-mediated Rac1/MAPK activation | Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1/MAPK signaling.
Jiang K, Lu Q, Li Q, Ji Y, Chen W, Xue X. | 04/15/2017 |
| Our results indicated that individuals carrying the VAV3 rs7528153 TT genotype were at a significantly increased risk of developing Paget's Disease of Bone | VAV3 Gene Polymorphism Is Associated with Paget's Disease of Bone.
Usategui-Martín R, Calero-Paniagua I, García-Aparicio J, Corral-Gudino L, Del Pino Montes J, González Sarmiento R., Free PMC Article | 04/8/2017 |
| Vav3 was accumulated in cell protrusions, contributed to the formation of membrane protrusions, and thereby increased the motility and invasiveness of pancreatic ductal adenocarcinoma cells | Vav3 is linked to poor prognosis of pancreatic cancers and promotes the motility and invasiveness of pancreatic cancer cells.
Tsuboi M, Taniuchi K, Furihata M, Naganuma S, Kimura M, Watanabe R, Shimizu T, Saito M, Dabanaka K, Hanazaki K, Saibara T. | 04/1/2017 |