| The effect of miR-372-5p regulation on CDX1 and CDX2 in the gastric cancer cell line. | The effect of miR-372-5p regulation on CDX1 and CDX2 in the gastric cancer cell line.
Gharakhyli EA, Tabar Molla Hassan A, Alipour M, Vahidi S, Samadani AA. | 10/11/2023 |
| LncRNA FOXD2-AS1 accelerates the progression of cervical cancer via downregulating CDX1. | LncRNA FOXD2-AS1 accelerates the progression of cervical cancer via downregulating CDX1.
Chen DZ, Wang TF, Dai WC, Xu X, Chen PF. | 11/21/2020 |
| This study shows that CDX1 contributes to the tumorigenesis and progression of gastric cancer and suggests the potential of targeting CDX1 to treat this malignancy. | CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis.
Choi SI, Yoon C, Park MR, Lee D, Kook MC, Lin JX, Kang JH, Ashktorab H, Smoot DT, Yoon SS, Cho SJ. | 08/1/2020 |
| Low CDX1 expression is correlated with Gastric Adenocarcinoma. | CDX1/2 and KLF5 Expression and Epigenetic Modulation of Sonic Hedgehog Signaling in Gastric Adenocarcinoma.
Samadani AA, Nikbakhsh N, Taheri H, Shafaee S, Fattahi S, Pilehchian Langroudi M, Hajian K, Akhavan-Niaki H. | 01/4/2020 |
| These data highlight a possible role of CDX1 in altering the N-glycosylation of colorectal cancer cells, which is a hallmark of tumor development. | N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines.
Holst S, Wilding JL, Koprowska K, Rombouts Y, Wuhrer M., Free PMC Article | 11/30/2019 |
| High CDX1 expression is associated with esophageal adenocarcinoma. | Campylobacter Concisus and Its Effect on the Expression of CDX1 and COX2.
Mozaffari Namin B, Soltan Dallal MM., Free PMC Article | 03/16/2019 |
| XIST is down-regulated in breast cancer and suppresses breast cancer cell growth, migration, and invasion via the miR-155/CDX1 axis. caudal-type homeobox 1 (CDX1) was identified as a direct target of miR-155 and miR-155/CDX1 rescued the effects of XIST in breast cancer cells. | Long non-coding RNA XIST inhibited breast cancer cell growth, migration, and invasion via miR-155/CDX1 axis.
Zheng R, Lin S, Guan L, Yuan H, Liu K, Liu C, Ye W, Liao Y, Jia J, Zhang R. | 04/14/2018 |
| Results identified CDX1 as cis methylation quantitative trait loci in allergic rhinitis. | Combining omics data to identify genes associated with allergic rhinitis.
Morin A, Laviolette M, Pastinen T, Boulet LP, Laprise C., Free PMC Article | 07/22/2017 |
| Downregulation of CDX1 is associated with recurrence in hepatocellular carcinoma. | Low CDX1 expression predicts a poor prognosis for hepatocellular carcinoma patients after hepatectomy.
Zheng H, Yang Y, Wang MC, Yuan SX, Tian T, Han J, Ni JS, Wang J, Xing H, Zhou WP. | 04/15/2017 |
| Data indicate an association between highly fucosylated glycans and caudal type homeobox 1 (CDX1) and/or villin mRNA expression that both correlate with cell differentiation. | N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.
Holst S, Deuss AJ, van Pelt GW, van Vliet SJ, Garcia-Vallejo JJ, Koeleman CA, Deelder AM, Mesker WE, Tollenaar RA, Rombouts Y, Wuhrer M., Free PMC Article | 10/22/2016 |
| Changes in CDX1/CDX2 mRNA expression in gastric mucosa following H. pylori eradication showed only insignificant results | Follow-Up Study on CDX1 and CDX2 mRNA Expression in Noncancerous Gastric Mucosae After Helicobacter pylori Eradication.
Shin CM, Kim N, Chang H, Kim JS, Lee DH, Jung HC. | 08/6/2016 |
| miR-215 is a link between CDX1 expression and BMI1 repression that governs differentiation in colorectal cancer | The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation.
Jones MF, Hara T, Francis P, Li XL, Bilke S, Zhu Y, Pineda M, Subramanian M, Bodmer WF, Lal A., Free PMC Article | 06/27/2015 |
| CDX1 restricts the invasion of HTR-8/SVneo trophoblast cells by inhibiting MMP-9 expression independently of the PI3K/AKT pathway. | CDX1 restricts the invasion of HTR-8/SVneo trophoblast cells by inhibiting MMP-9 expression.
Jia RZ, Rui C, Li JY, Cui XW, Wang X. | 05/16/2015 |
| Results showed an anti-growth effect of CDX1 and identified its miRNA regulatory mechanism in gastric cancer. | MicroRNA-296-5p increases proliferation in gastric cancer through repression of Caudal-related homeobox 1.
Li T, Lu YY, Zhao XD, Guo HQ, Liu CH, Li H, Zhou L, Han YN, Wu KC, Nie YZ, Shi YQ, Fan DM. | 06/28/2014 |
| Certain SNPs of Cdx1 and Cdx2 and their interactions with other risk factors are associated with Barrett's esophagus (BE) and may contribute to human susceptibility to BE. | Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus.
Ren D, Zheng G, Bream S, Tevebaugh W, Shaheen NJ, Chen X., Free PMC Article | 03/8/2014 |
| The differential regulation of the gene expression of CDX1, CDX2 and SOX2 in patients with gastric cancer affects not only the tumour but also the non-neoplastic tumour-distant mucosa. | Dysregulation of CDX1, CDX2 and SOX2 in patients with gastric cancer also affects the non-malignant mucosa.
Bornschein J, Tóth K, Selgrad M, Kuester D, Wex T, Molnár B, Tulassay Z, Malfertheiner P. | 11/2/2013 |
| Data indicate that autophagy is activated though the Cdx1-Bcl-2-LC3 pathway. | Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells.
Wu S, Wang X, Chen J, Chen Y. | 08/31/2013 |
| Oxidative stress regulates CDX1 expression in T84 colorectal cancer cells. | Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells.
Zhang R, Kang KA, Kim KC, Na SY, Chang WY, Kim GY, Kim HS, Hyun JW. | 08/10/2013 |
| The findings represented the relation between CDX1 mutations and CDX1 genotype. Furthermore, it was suggested that the downregulation of CDX1 might be related to the development of Anorectal malformations . | Mutations and down-regulation of CDX1 in children with anorectal malformations.
Zhang T, Tang XB, Wang LL, Bai YZ, Qiu GR, Yuan ZW, Wang WL., Free PMC Article | 07/13/2013 |
| analysis of an IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma | Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma.
Nyquist KB, Panagopoulos I, Thorsen J, Haugom L, Gorunova L, Bjerkehagen B, Fosså A, Guriby M, Nome T, Lothe RA, Skotheim RI, Heim S, Micci F., Free PMC Article | 05/25/2013 |
| The homeotic transcription factor CDX1 is expressed in the intestinal epithelium at all stages of development. Review. | [Identity and intestinal pathologies: the Cdx2 homeotic gene].
Freund JN. | 05/18/2013 |
| SALL4 and KLF5 were aberrantly expressed in the CDX1(+) intestinal metaplasia of the stomach. Sustained expression of CDX1 gave rise to the induction of early intestinal-stemness markers, followed by the expression of intestinal-differentiation markers. | CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5.
Fujii Y, Yoshihashi K, Suzuki H, Tsutsumi S, Mutoh H, Maeda S, Yamagata Y, Seto Y, Aburatani H, Hatakeyama M., Free PMC Article | 03/2/2013 |
| The epigenetic inactivation of CDX1 by promoter methylation, as well as the functional link of CDX1 promoter methylation to the inflammatory NF-kappaB signaling pathway, were investigated. | Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach.
Rau TT, Rogler A, Frischauf M, Jung A, Konturek PC, Dimmler A, Faller G, Sehnert B, El-Rifai W, Hartmann A, Voll RE, Schneider-Stock R., Free PMC Article | 12/8/2012 |
| The human ASBT promoter was activated transcriptionally by CDX1 and CDX2. | Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2.
Ma L, Jüttner M, Kullak-Ublick GA, Eloranta JJ. | 02/18/2012 |
| Expression of CDX1 and CDX4 is not correlated with the pathogenesis and relapse of adult ALL. | [Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].
Lu HY, Xia HL, Chen XW, Zhu LX, Wang QY, Cheng X. | 01/14/2012 |