| Tubulin Alpha-1b as a Potential Biomarker for Lung Adenocarcinoma Diagnosis and Prognosis. | Tubulin Alpha-1b as a Potential Biomarker for Lung Adenocarcinoma Diagnosis and Prognosis.
Pang XL, Du HF, Nie F, Yang XG, Xu Y., Free PMC Article | 11/3/2023 |
| Integrated regulation of tubulin tyrosination and microtubule stability by human alpha-tubulin isotypes. | Integrated regulation of tubulin tyrosination and microtubule stability by human α-tubulin isotypes.
Fu G, Yan S, Khoo CJ, Chao VC, Liu Z, Mukhi M, Hervas R, Li XD, Ti SC. | 10/16/2023 |
| Dynamic Network Biomarker of Pre-Exhausted CD8(+) T Cells Contributed to T Cell Exhaustion in Colorectal Cancer. | Dynamic Network Biomarker of Pre-Exhausted CD8(+) T Cells Contributed to T Cell Exhaustion in Colorectal Cancer.
Hu J, Han C, Zhong J, Liu H, Liu R, Luo W, Chen P, Ling F., Free PMC Article | 11/6/2021 |
| Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder. | Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.
Snelleksz M, Dean B. | 10/30/2021 |
| The Expression and Potential Role of Tubulin Alpha 1b in Wilms' Tumor. | The Expression and Potential Role of Tubulin Alpha 1b in Wilms' Tumor.
Xu QQ, Qin LT, Liang SW, Chen P, Gu JH, Huang ZG, Yang X, Gao L, Wang SS, Luo YG, Liu LL, Wang J, Lin JY, Chen G, Chen JB., Free PMC Article | 05/22/2021 |
| Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. | Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.
Han H, Schubert HL, McCullough J, Monroe N, Purdy MD, Yeager M, Sundquist WI, Hill CP., Free PMC Article | 09/19/2020 |
| Data show that retinal endothelial cells (HREC) treated with low molecular weight fraction of commercial 5% human serum albumin (LMWF5A) exhibit a rapid increase in the amount and distribution of acetylated alpha-tubulin. | The low molecular weight fraction of commercial human serum albumin induces acetylation of α-tubulin and reduces transcytosis in retinal endothelial cells.
Thomas GW, Rael LT, Hausburg M, Frederick ED, Brody E, Bar-Or D. | 06/24/2017 |
| The C-terminal tail from the tubulin beta I isotype, but not the beta III isotype, formed contacts in the putative binding site of a recently discovered antineoplastic peptide that disrupts microtubule formation in glioma cells. | Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in β-Tubulin Isotypes.
Laurin Y, Eyer J, Robert CH, Prevost C, Sacquin-Mora S. | 06/3/2017 |
| TUBA1B/ESR1 gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis. | Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling.
Ma M, Chen X, Lu L, Yuan F, Zeng W, Luo S, Yin F, Cai J. | 01/14/2017 |
| Taken together our data provide valuable information regarding the interaction of CK1delta and a-tubulin and a novel approach for the development of pharmacological tools to inhibit proliferation of cancer cells. | New potential peptide therapeutics perturbing CK1δ/α-tubulin interaction.
Krüger M, Kalbacher H, Kastritis PL, Bischof J, Barth H, Henne-Bruns D, Vorgias C, Sarno S, Pinna LA, Knippschild U. | 08/27/2016 |
| Results suggest that lithium chloride (LiCl) treatments activate alpha-tubulin N-acetyltransferase 1 (alphaTAT1) by the inhibition of glycogen synthase kinase 3 beta (GSK-3beta) and promote the alpha-tubulin acetylation, and then elongate the primary cilia. | The elongation of primary cilia via the acetylation of α-tubulin by the treatment with lithium chloride in human fibroblast KD cells.
Nakakura T, Asano-Hoshino A, Suzuki T, Arisawa K, Tanaka H, Sekino Y, Kiuchi Y, Kawai K, Hagiwara H. | 01/16/2016 |
| NAD-dependent regulation of alpha-tubulin acetylation is mediated by SIRT2. | Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels.
Skoge RH, Dölle C, Ziegler M. | 08/8/2015 |
| Data indicate that the derivatives exhibited much better potency to inhibit tubulin polymerization but a decreased activity to inhibit Hsp27 chaperone function. | Synthesis and anticancer mechanism investigation of dual Hsp27 and tubulin inhibitors.
Zhong B, Chennamaneni S, Lama R, Yi X, Geldenhuys WJ, Pink JJ, Dowlati A, Xu Y, Zhou A, Su B., Free PMC Article | 03/15/2014 |
| Increased TUBA1B expression is associated with poor overall survival in hepatocellular carcinoma. | Increased α-tubulin1b expression indicates poor prognosis and resistance to chemotherapy in hepatocellular carcinoma.
Lu C, Zhang J, He S, Wan C, Shan A, Wang Y, Yu L, Liu G, Chen K, Shi J, Zhang Y, Ni R. | 11/30/2013 |
| ARHGAP21 is a Rho-GAP involved in cell-cell junction remodeling that affects migration and EMT through alpha-tubulin interaction and acetylation | ARHGAP21 protein, a new partner of α-tubulin involved in cell-cell adhesion formation and essential for epithelial-mesenchymal transition.
Barcellos KS, Bigarella CL, Wagner MV, Vieira KP, Lazarini M, Langford PR, Machado-Neto JA, Call SG, Staley DM, Chung JY, Hansen MD, Saad ST., Free PMC Article | 04/6/2013 |
| TQ induced a concentration- and time-dependent degradation of alpha/beta tubulin in both cancer cell types. | Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts.
Alhosin M, Ibrahim A, Boukhari A, Sharif T, Gies JP, Auger C, Schini-Kerth VB. | 04/6/2013 |
| the ethyl acetate extract of Lactuca sativa induced HL-60 cell death, which correlated with the acetylation of alpha-tubulin. | Anti-leukaemic effects of two extract types of Lactuca sativa correlate with the activation of Chk2, induction of p21, downregulation of cyclin D1 and acetylation of alpha-tubulin.
Gridling M, Popescu R, Kopp B, Wagner KH, Krenn L, Krupitza G. | 06/28/2010 |
| Confocal microscopic analyses showed co-localization of the TaSP protein with alpha-tubulin and reciprocal immuno-co-precipitation experiments demonstrated an association of TaSP with alpha-tubulin in vivo. | Schizonts of Theileria annulata interact with the microtubuli network of their host cell via the membrane protein TaSP.
Seitzer U, Gerber S, Beyer D, Dobschanski J, Kullmann B, Haller D, Ahmed JS. | 06/28/2010 |
| This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia | Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia.
Martins-de-Souza D, Schmitt A, Röder R, Lebar M, Schneider-Axmann T, Falkai P, Turck CW. | 04/22/2010 |
| Data show that 4-oxo-4-HPR inhibited tubulin polymerization and modulated gene expression of spindle aberration associated genes Kif 1C, Kif 2A, Eg5, Tara, tankyrase-1, centractin, and TOGp. | Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity.
Appierto V, Tiberio P, Cavadini E, Casalini P, Cappelletti G, Formelli F. | 03/29/2010 |
| These results imply that MeCP2 is involved in the regulation of neuronal alpha-tubulin and add molecular evidence that reversal of the effects of MeCP2 deficiency is achievable | MeCP2 involvement in the regulation of neuronal alpha-tubulin production.
Abuhatzira L, Shemer R, Razin A. | 01/21/2010 |
| Increased expression of centrosomal TUBA1B in atypical ductal hyperplasia and carcinoma of the breast is reported. | Increased expression of centrosomal alpha, gamma-tubulin in atypical ductal hyperplasia and carcinoma of the breast.
Niu Y, Liu T, Tse GM, Sun B, Niu R, Li HM, Wang H, Yang Y, Ye X, Wang Y, Yu Q, Zhang F., Free PMC Article | 01/21/2010 |
| alpha-tubulin interacted with ARL7. | ADP-ribosylation factor like 7 (ARL7) interacts with alpha-tubulin and modulates intracellular vesicular transport.
Wei SM, Xie CG, Abe Y, Cai JT. | 01/21/2010 |
| This protein has been found differentially expressed in the Wernicke's Area from patients with schizophrenia. | Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation.
Martins-de-Souza D, Gattaz WF, Schmitt A, Novello JC, Marangoni S, Turck CW, Dias-Neto E., Free PMC Article | 05/29/2009 |
| mitochondrial ribosomal protein S12 3'-UTR interacts specifically with TRAP1 (tumor necrosis factor receptor-associated protein1), hnRNPM4 (heterogeneous nuclear ribonucleoprotein M4), Hsp70 and Hsp60 (heat shock proteins 70 and 60), and alpha-tubulin | cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins.
Russo A, Cirulli C, Amoresano A, Pucci P, Pietropaolo C, Russo G. | 01/21/2010 |