| Novel LAMC3 pathogenic variant enriched in Finnish population causes malformations of cortical development and severe epilepsy. | Novel LAMC3 pathogenic variant enriched in Finnish population causes malformations of cortical development and severe epilepsy.
Saarela A, Timonen O, Kirjavainen J, Liu Y, Silvennoinen K, Mervaala E, Kälviäinen R. | 08/27/2024 |
| [Relationships between decreased LAMC3 and poor prognosis in ovarian cancer]. | [Relationships between decreased LAMC3 and poor prognosis in ovarian cancer].
Lei SM, Liu X, Xia LP, Ke Y, Wei LW, Li L, Yin FJ. | 09/18/2021 |
| LAMC3 mutation causes structural and functional impairments in visual attention networks. | Homozygous LAMC3 mutation links to structural and functional changes in visual attention networks.
Urgen BM, Topac Y, Ustun FS, Demirayak P, Oguz KK, Kansu T, Saygi S, Ozcelik T, Boyaci H, Doerschner K. | 02/1/2020 |
| These data demonstrate a unique temporal and spatial expression for laminins and reveal a novel role for laminin gamma3 during human retinogenesis. | Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation.
Dorgau B, Felemban M, Sharpe A, Bauer R, Hallam D, Steel DH, Lindsay S, Mellough C, Lako M., Free PMC Article | 11/9/2019 |
| Study reports a novel mutation in LAMC3 associated with generalized polymicrogyria of the cortex and epilepsy. Study identified a homozygous nonsense mutation in LAMC3: c.3190C>T (p.Gln1064*). | A novel mutation in LAMC3 associated with generalized polymicrogyria of the cortex and epilepsy.
Zambonin JL, Dyment DA, Xi Y, Lamont RE, Hartley T, Miller E, Kerr M, Care4Rare Canada Consortium, Boycott KM, Parboosingh JS, Venkateswaran S. | 10/5/2019 |
| LAMC3 gene variation is associated with oral cavity and pharyngeal cancer. | Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
Lesseur C, Diergaarde B, Olshan AF, Wünsch-Filho V, Ness AR, Liu G, Lacko M, Eluf-Neto J, Franceschi S, Lagiou P, Macfarlane GJ, Richiardi L, Boccia S, Polesel J, Kjaerheim K, Zaridze D, Johansson M, Menezes AM, Curado MP, Robinson M, Ahrens W, Canova C, Znaor A, Castellsagué X, Conway DI, Holcátová I, Mates D, Vilensky M, Healy CM, Szeszenia-Dąbrowska N, Fabiánová E, Lissowska J, Grandis JR, Weissler MC, Tajara EH, Nunes FD, de Carvalho MB, Thomas S, Hung RJ, Peters WH, Herrero R, Cadoni G, Bueno-de-Mesquita HB, Steffen A, Agudo A, Shangina O, Xiao X, Gaborieau V, Chabrier A, Anantharaman D, Boffetta P, Amos CI, McKay JD, Brennan P., Free PMC Article | 09/9/2017 |
| We found statistically significant association with AAO for three genes (WRN, NTN4 and LAMC3) with common associated variants. | Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data.
Saad M, Brkanac Z, Wijsman EM., Free PMC Article | 11/12/2016 |
| These data suggest that beta2 and gamma3-containing laminins play an important dose-dependent role in development of the cortical pial basement membrane | β2 and γ3 laminins are critical cortical basement membrane components: ablation of Lamb2 and Lamc3 genes disrupts cortical lamination and produces dysplasia.
Radner S, Banos C, Bachay G, Li YN, Hunter DD, Brunken WJ, Yee KT. | 07/27/2013 |
| Recessive LAMC3 mutations cause malformations of occipital cortical development. | Recessive LAMC3 mutations cause malformations of occipital cortical development.
Barak T, Kwan KY, Louvi A, Demirbilek V, Saygı S, Tüysüz B, Choi M, Boyacı H, Doerschner K, Zhu Y, Kaymakçalan H, Yılmaz S, Bakırcıoğlu M, Cağlayan AO, Oztürk AK, Yasuno K, Brunken WJ, Atalar E, Yalçınkaya C, Dinçer A, Bronen RA, Mane S, Ozçelik T, Lifton RP, Sestan N, Bilgüvar K, Günel M., Free PMC Article | 07/30/2011 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesNew genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. | 04/7/2010 |
| Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains | Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains.
Ido H, Ito S, Taniguchi Y, Hayashi M, Sato-Nishiuchi R, Sanzen N, Hayashi Y, Futaki S, Sekiguchi K., Free PMC Article | 01/21/2010 |