| Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization. | Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization.
White-Gilbertson S, Lu P, Saatci O, Sahin O, Delaney JR, Ogretmen B, Voelkel-Johnson C., Free PMC Article | 05/24/2024 |
| ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells. | ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells.
Deng T, Xie L, Xiaofang C, Zhang Z, Xiao Y, Peng Y, Yin L, Fu Y, Li X., Free PMC Article | 03/1/2024 |
| Deoxyribonuclease 1-like 3 inhibits colorectal malignancy through antagonizing NEDD4-triggered CDKN1A ubiquitination. | Deoxyribonuclease 1-like 3 inhibits colorectal malignancy through antagonizing NEDD4-triggered CDKN1A ubiquitination.
Yu L, Huang J. | 02/16/2024 |
| p21 Prevents the Exhaustion of CD4[+] T Cells Within the Antitumor Immune Response Against Colorectal Cancer. | p21 Prevents the Exhaustion of CD4(+) T Cells Within the Antitumor Immune Response Against Colorectal Cancer.
Thoma OM, Naschberger E, Kubánková M, Larafa I, Kramer V, Menchicchi B, Merkel S, Britzen-Laurent N, Jefremow A, Grützmann R, Koop K, Neufert C, Atreya R, Guck J, Stürzl M, Neurath MF, Waldner MJ. | 01/30/2024 |
| CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression. | CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression.
Shuai Y, Zhang H, Liu C, Wang J, Jiang Y, Sun J, Gao X, Bo X, Xiao X, Liao X, Huang C, Chen H, Jiang G., Free PMC Article | 01/26/2024 |
| CDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution? | CDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution?
Manousakis E, Miralles CM, Esquerda MG, Wright RHG., Free PMC Article | 01/12/2024 |
| Long non-coding RNA generated from CDKN1A gene by alternative polyadenylation regulates p21 expression during DNA damage response. | Long non-coding RNA generated from CDKN1A gene by alternative polyadenylation regulates p21 expression during DNA damage response.
Murphy MR, Ramadei A, Doymaz A, Varriano S, Natelson DM, Yu A, Aktas S, Mazzeo M, Mazzeo M, Zakusilo G, Kleiman FE., Free PMC Article | 12/1/2023 |
| A candidate prognostic biomarker: TFEB inhibits tumor progression via elevating CDKN1A in bladder cancer. | A candidate prognostic biomarker: TFEB inhibits tumor progression via elevating CDKN1A in bladder cancer.
Yue M, Yang Z, Sun J, Liu Z. | 11/30/2023 |
| Elevated CDKN1A (P21) mediates beta-thalassemia erythroid apoptosis, but its loss does not improve beta-thalassemic erythropoiesis. | Elevated CDKN1A (P21) mediates β-thalassemia erythroid apoptosis, but its loss does not improve β-thalassemic erythropoiesis.
Liang R, Lin M, Menon V, Qiu J, Menon A, Breda L, Arif T, Rivella S, Ghaffari S., Free PMC Article | 11/20/2023 |
| Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme. | Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme.
Cheng WY, Shen CC, Liang YJ, Chiao MT, Yang YC, Hsieh WY, Lin CH, Chen JP., Free PMC Article | 09/25/2023 |
| TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus. | TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus.
Macedo JMB, Silva AL, Pinto AC, Landeira LFL, Portari EA, Santos-Rebouças CB, Klumb EM. | 08/28/2023 |
| A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21. | A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21.
Bélanger F, Roussel C, Sawchyn C, St-Hilaire E, Gezzar-Dandashi S, Kimenyi Ishimwe AB, Mallette FA, Wurtele H, Drobetsky E., Free PMC Article | 08/4/2023 |
| G9a and DNMT1 inhibition modulates CDKN1A promoter methylation and the cell cycle leading to improvement in kidney fibrosis. | G9a and DNMT1 inhibition modulates CDKN1A promoter methylation and the cell cycle leading to improvement in kidney fibrosis.
Yang Y, Zhou Z, Wang L, Gao P, Wu Z. | 08/1/2023 |
| MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo. | MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo.
Liang Y, Wu D, Qu Q, Li Z, Yin H. | 07/21/2023 |
| TP53 (rs1042522, rs28934571) and TP21 (rs1801270, rs1059234) Polymorphisms and Risk of Breast Cancer among Rural Women of Maharashtra: Findings from a Hospital Based Case- Control Study. | TP53 (rs1042522, rs28934571) and TP21 (rs1801270, rs1059234) Polymorphisms and Risk of Breast Cancer among Rural Women of Maharashtra: Findings from a Hospital Based Case- Control Study.
Datkhile KD, Bhosale SJ, Durgawale PP, Jagdale NJ, More AL, Gudur RA, Gudur AK, Patil SR., Free PMC Article | 06/2/2023 |
| Extracellular vesicles derived from cervical cancer cells carrying MCM3AP-AS1 promote angiogenesis and tumor growth in cervical cancer via the miR-93/p21 axis. | Extracellular vesicles derived from cervical cancer cells carrying MCM3AP-AS1 promote angiogenesis and tumor growth in cervical cancer via the miR-93/p21 axis.
Mo Y, Liang Z, Lan L, Xiong X, Zhang C, Liu W, Huang H, Fan J, Yang L. | 06/2/2023 |
| The Interplay between Noncoding RNAs and p21 Signaling in Gastrointestinal Cancer: From Tumorigenesis to Metastasis. | The Interplay between Noncoding RNAs and p21 Signaling in Gastrointestinal Cancer: From Tumorigenesis to Metastasis.
Rahmani F, Zandigohar M, Safavi P, Behzadi M, Ghorbani Z, Payazdan M, Ferns G, Hassanian SM, Avan A. | 05/30/2023 |
| N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21[cip1/waf1]/CDK2-Cyclin E1 axis-mediated cell cycle transition. | N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A., Free PMC Article | 05/19/2023 |
| Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway. | Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway.
Feng R, Wang X, Chen H, Cao C, Liu T, Zhao T, Chen H, Tian R, Ni Y, Tian X, Hu Z, Ma J, Gong D. | 02/13/2023 |
| Epstein-Barr virus miR-BART2-5p and miR-BART11-5p regulate cell proliferation, apoptosis, and migration by targeting RB and p21 in gastric carcinoma. | Epstein-Barr virus miR-BART2-5p and miR-BART11-5p regulate cell proliferation, apoptosis, and migration by targeting RB and p21 in gastric carcinoma.
Zhao MH, Liu W, Zhang X, Zhang Y, Luo B. | 01/21/2023 |
| Genome-Wide Association Study Identifies CDKN1A as a Novel Locus Associated with Muscle Fiber Composition. | Genome-Wide Association Study Identifies CDKN1A as a Novel Locus Associated with Muscle Fiber Composition.
Semenova EA, Zempo H, Miyamoto-Mikami E, Kumagai H, Larin AK, Sultanov RI, Babalyan KA, Zhelankin AV, Tobina T, Shiose K, Kakigi R, Tsuzuki T, Ichinoseki-Sekine N, Kobayashi H, Naito H, Burniston J, Generozov EV, Fuku N, Ahmetov II., Free PMC Article | 12/31/2022 |
| Gene polymorphisms of cyclin-dependent kinase inhibitor and matrix metalloproteinase-9 in Sudanese patients with esophageal squamous cell carcinoma. | Gene polymorphisms of cyclin-dependent kinase inhibitor and matrix metalloproteinase-9 in Sudanese patients with esophageal squamous cell carcinoma.
Eltayeb MM, Ali MM, Omar SM, Mohamed NS, Adam I, Hamdan HZ., Free PMC Article | 12/24/2022 |
| Inhibition of p21 activates Akt kinase to trigger ROS-induced autophagy and impacts on tumor growth rate. | Inhibition of p21 activates Akt kinase to trigger ROS-induced autophagy and impacts on tumor growth rate.
Maheshwari M, Yadav N, Hasanain M, Pandey P, Sahai R, Choyal K, Singh A, Nengroo MA, Saini KK, Kumar D, Mitra K, Datta D, Sarkar J., Free PMC Article | 12/24/2022 |
| Protective roles of cytoplasmic p21[Cip1] [/Waf1] in senolysis and ferroptosis of lung cancer cells. | Protective roles of cytoplasmic p21(Cip1) (/Waf1) in senolysis and ferroptosis of lung cancer cells.
Koyanagi A, Kotani H, Iida Y, Tanino R, Kartika ID, Kishimoto K, Harada M., Free PMC Article | 12/10/2022 |
| P16 and P21 are involved in the pathogenesis of endometrial thinning: A cross-sectional study. | P16 and P21 are involved in the pathogenesis of endometrial thinning: A cross-sectional study.
Le A, Li Q, Zheng X, Yang H., Free PMC Article | 10/22/2022 |