Pathogenesis of psoriasis via miR-149-5p/AKT1axis by long noncoding RNA BLACAT1. | Pathogenesis of psoriasis via miR-149-5p/AKT1axis by long noncoding RNA BLACAT1. Hua X, Li J, Shang M, He W, Gao P, Min L, Peng X., Free PMC Article | 08/25/2023 |
Urinary BLACAT1 as a non-invasive biomarker for bladder cancer. | Urinary BLACAT1 as a non-invasive biomarker for bladder cancer. El Sharkawi FZ, El Sabah M, Atya HB, Khaled HM., Free PMC Article | 05/8/2023 |
Role of BLACAT1 in IL-1beta-Induced Human Articular Chondrocyte Apoptosis and Extracellular Matrix Degradation via the miR-149-5p/ HMGCR Axis. | Role of BLACAT1 in IL-1β-Induced Human Articular Chondrocyte Apoptosis and Extracellular Matrix Degradation via the miR-149-5p/ HMGCR Axis. Li Z, Wang Y, Wu Y, Liu Y, Zhao Y, Chen X, Li M, Zhao R. | 10/15/2022 |
Yin Yang 1-stimulated long noncoding RNA bladder cancer-associated transcript 1 upregulation facilitates esophageal carcinoma progression via the microRNA-5590-3p/programmed cell death-ligand 1 pathway. | Yin Yang 1-stimulated long noncoding RNA bladder cancer-associated transcript 1 upregulation facilitates esophageal carcinoma progression via the microRNA-5590-3p/programmed cell death-ligand 1 pathway. Cheng J, Yang Q, Han X, Wang H, Wu K, Zhao H., Free PMC Article | 04/30/2022 |
LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis. | LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis. Liao B, Chen S, Li Y, Yang Z, Yang Y, Deng X, Ke S., Free PMC Article | 11/22/2021 |
Effect of lncRNA-BLACAT1 on drug resistance of non-small cell lung cancer cells in DDP chemotherapy by regulating cyclin D1 expression. | Effect of lncRNA-BLACAT1 on drug resistance of non-small cell lung cancer cells in DDP chemotherapy by regulating cyclin D1 expression. Ju ZS, Sun B, Bao D, Zhang XF. | 05/8/2021 |
Up-regulation of long non-coding RNA BLACAT1 predicts aggressive clinicopathologic characteristics and poor prognosis of glioma. | Up-regulation of long non-coding RNA BLACAT1 predicts aggressive clinicopathologic characteristics and poor prognosis of glioma. Zhang X, Wei X, Liu J, Yang J, Jin P., Free PMC Article | 03/27/2021 |
Transcription factor ZNF703 activates linc-UBC1 to stimulate the progression of glioma. | Transcription factor ZNF703 activates linc-UBC1 to stimulate the progression of glioma. Wang J, Zhu LS, Luo Y, Wang CH, Wei YY, Zhou LM. | 03/20/2021 |
Linc-UBC1 stimulates the metastasis and progression of ovarian cancer via downregulating p53 level. | Linc-UBC1 stimulates the metastasis and progression of ovarian cancer via downregulating p53 level. Liu H, Zeng SY, Xie Y, Fei CQ, Sun L. | 02/13/2021 |
Expression and Diagnostic Value of lncRNA BLACAT1 in Peripheral Blood of Patients with Acute Myeloid Leukemia. | Expression and Diagnostic Value of lncRNA BLACAT1 in Peripheral Blood of Patients with Acute Myeloid Leukemia. Wu X, Wang J, Li D, Xu Z. | 01/9/2021 |
LncRNA BLACAT1 Is Upregulated in Cervical Squamous Cell Carcinoma (CSCC) and Predicts Poor Survival. | LncRNA BLACAT1 Is Upregulated in Cervical Squamous Cell Carcinoma (CSCC) and Predicts Poor Survival. Cheng H, Tian J, Wang C, Ren L, Wang N. | 12/12/2020 |
Long non-coding RNA BLACAT1 inhibits prostate cancer cell proliferation through sponging miR-361. | Long non-coding RNA BLACAT1 inhibits prostate cancer cell proliferation through sponging miR-361. Li HY, Jiang FQ, Chu L, Wei X. | 11/21/2020 |
Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/beta-catenin signaling pathway via regulating miR-519d-3p. | Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p. Yang H, Qi Y, Wang XL, Gu JJ, Shi TM. | 10/24/2020 |
BLACAT1 is negatively associated with prognosis in patients with NSCLC and inhibits cell progression, metastasis and epithelial-mesenchymal transition through down-regulating Wnt/beta-catenin signaling pathway. | BLACAT1 is negatively associated with prognosis in patients with NSCLC and inhibits cell progression, metastasis and epithelial-mesenchymal transition through down-regulating Wnt/β-catenin signaling pathway. Xu R, Cao XR, Zhang BQ, Wang JL, Wang L, Sun WQ. | 10/3/2020 |
this study highlights the important roles of BLACAT1/miR-605-3p/VASP axis in glioma progression. | LncRNA BLACAT1 regulates VASP expression via binding to miR-605-3p and promotes giloma development. Liu N, Hu G, Wang H, Wang Y, Guo Z. | 06/13/2020 |
BLACAT1 knockdown enhanced radioresistance of head and neck squamous cell carcinoma cells via regulating PSEN1, exposing the probable target role of BLACAT1 in head and neck squamous cell carcinoma. This was the first time that the pivotal role of BLACAT1 was investigated in head and neck squamous cell carcinoma, which provided a novel therapeutic direction for head and neck squamous cell carcinoma patients. | Knockdown of lncRNA BLACAT1 enhances radiosensitivity of head and neck squamous cell carcinoma cells by regulating PSEN1. Gou C, Han P, Li J, Gao L, Ji X, Dong F, Su Q, Zhang Y, Liu X., Free PMC Article | 03/28/2020 |
BLACAT1 is aberrantly upregulated in hepatocellular carcinoma (HCC) and its inhibition had tumor suppressing effects in human HCC, possibly through endogenously competing against has-miR-485-5p. | Long noncoding RNA BLACAT1 is overexpressed in hepatocellular carcinoma and its downregulation suppressed cancer cell development through endogenously competing against hsa-miR-485-5p. Peng Y, Leng W, Duan S, Hong M. | 01/18/2020 |
the expression of BLACAT1 had no significant association with age (p = 0.92), gender (p = 0.55), and smoking (p = 0.62). CONCLUSION: High expression of lncRNA BLACAT1 may predict a poor prognosis in OS, TNM stage, tumor grade, and LNM. Its predictive roles were not significantly affected by age, gender, or smoking. Therefore, lncRNA BLACAT1 may serve as a promising predictor in cancer prognosis. | LncRNA BLACAT1 May Serve as a Prognostic Predictor in Cancer: Evidence from a Meta-Analysis. Lu H, Liu H, Yang X, Ye T, Lv P, Wu X, Ye Z., Free PMC Article | 09/7/2019 |
LncRNA BLACAT1 contributes to the proliferation and migration of osteosarcoma cells by regulating STAT3 | LncRNA BLACAT1 accelerates the proliferation and migration of osteosarcoma cells through regulating STAT3. Dong Z, Wang Y. | 04/13/2019 |
Study identified that BLACAT1 was upregulated in cisplatin (DDP)resistant nonsmall cell lung cancer (NSCLC) cells, and confirmed the interaction of lncRNA BLACAT1 and miR17. In addition, lncRNA BLACAT1 facilitated autophagy through the miR17/ATG7 signaling pathway, thus promoting chemoresistance of NSCLC cells. | LncRNA BLACAT1 is involved in chemoresistance of non‑small cell lung cancer cells by regulating autophagy. Huang FX, Chen HJ, Zheng FX, Gao ZY, Sun PF, Peng Q, Liu Y, Deng X, Huang YH, Zhao C, Miao LJ. | 03/16/2019 |
results indicate that linc-UBC1 is a novel oncogene in tumorigenesis and could promote the metastasis via EZH2 and E-cadherin in esophageal squamous cell carcinoma | Long noncoding RNA linc-UBC1 promotes tumor invasion and metastasis by regulating EZH2 and repressing E-cadherin in esophageal squamous cell carcinoma. Niu G, Zhuang H, Li B, Cao G. | 02/2/2019 |
our results conclude that BLACAT1 accelerates the oxaliplatin-resistance of gastric cancer via promoting ABCB1 protein expression by targeting miR-361, providing a novel insight for the chemoresistance of gastric cancer. | Long noncoding RNA BLACAT1 modulates ABCB1 to promote oxaliplatin resistance of gastric cancer via sponging miR-361. Wu X, Zheng Y, Han B, Dong X. | 09/22/2018 |
Mechanistic investigations demonstrated that BLACAT1 had a key role in G1/G0 arrest, and showed that BLACAT1 can repress p15 expression by binding to EZH2, thus contributing to the regulation of CRC cell cycle and proliferation. Our results suggest that BLACAT1, as a cell cycle regulator, may serve as a potential target for colon cancer prevention and treatment in human CRC | Long noncoding RNA BLACAT1 indicates a poor prognosis of colorectal cancer and affects cell proliferation by epigenetically silencing of p15. Su J, Zhang E, Han L, Yin D, Liu Z, He X, Zhang Y, Lin F, Lin Q, Mao P, Mao W, Shen D., Free PMC Article | 11/4/2017 |
combining experiments of miR-144 and BLACAT1 indicated that miR-144 could reverse the function of BLACAT1 on nonsmall cell lung cancer | Long Noncoding RNA Bladder Cancer Associated Transcript 1 Promotes the Proliferation, Migration, and Invasion of Nonsmall Cell Lung Cancer Through Sponging miR-144. Ye JR, Liu L, Zheng F. | 10/21/2017 |
Our study suggests that linc-UBC1 may represent a novel diagnostic, prognostic biomarker and a potential therapeutic target of gastric cancer | Long noncoding RNA linc-UBC1 is negative prognostic factor and exhibits tumor pro-oncogenic activity in gastric cancer. Hu Y, Pan J, Wang Y, Li L, Huang Y., Free PMC Article | 12/12/2015 |