| Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin beta1 in Kawasaki disease. | Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease.
Huang J, Zhao C, Zhang S., Free PMC Article | 05/16/2024 |
| PLXNC1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of IL-1beta-exposed chondrocytes via suppressing GRP78 expression. | PLXNC1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of IL-1β-exposed chondrocytes via suppressing GRP78 expression.
Meng N, Mao L, Jiang Q, Yuan J, Liu L, Wang L., Free PMC Article | 10/30/2023 |
| The Relationship Between Plexin C1 Overexpression and Survival in Hepatocellular Carcinoma: a Turkish Oncology Group (TOG) Study. | The Relationship Between Plexin C1 Overexpression and Survival in Hepatocellular Carcinoma: a Turkish Oncology Group (TOG) Study.
NazimTurhal S, Dogan M, Esendagli G, Artac M, Korkmaz L, Coskun HS, Goker E, PerranYumuk F, Bilgetekin I, Kose F, Uncu D, Kavgaci H, Akyol G, Ozet A, Yagci T. | 06/18/2022 |
| Results indicated that PLXNC1 was a direct target of miR-4500. Its knockdown inhibits proliferation and invasion of papillary thyroid cancer (PTC) cells. On the contrary, its overexpression of impairs miR-4500-induced inhibition of PTC malignancy. | MiR-4500 Regulates PLXNC1 and Inhibits Papillary Thyroid Cancer Progression.
Li R, Teng X, Zhu H, Han T, Liu Q., Free PMC Article | 05/9/2020 |
| Results indicate that long non-coding RNA (lncRNA) CASC2 can promote PLXNC1 expression by sponging miR-181a, thereby inhibiting the proliferation and invasion of melanoma cells. | Long non-coding RNA CASC2 inhibits tumorigenesis via the miR-181a/PLXNC1 axis in melanoma.
Wang Z, Wang X, Zhou H, Dan X, Jiang L, Wu Y. | 10/6/2018 |
| Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis | Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis.
Peng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo-Maya JD, Kaminski N, Hu X, Pan H, Ryu C, Osafo-Addo A, Homer RJ, Feghali-Bostwick C, Fares WH, Gulati M, Hu B, Lee CG, Elias JA, Herzog EL., Free PMC Article | 09/23/2017 |
| loss of Plexin C1 in melanoma may promote early steps in melanoma progression through suppression of migration and proliferation | The neural guidance receptor Plexin C1 delays melanoma progression.
Chen Y, Soong J, Mohanty S, Xu L, Scott G., Free PMC Article | 12/7/2013 |
| Study reports the structures of Sema7A and A39R complexed with the Semaphorin-binding module of PlexinC1; both structures show two PlexinC1 molecules symmetrically bridged by Semaphorin dimers. | Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1.
Liu H, Juo ZS, Shim AH, Focia PJ, Chen X, Garcia KC, He X., Free PMC Article | 09/27/2010 |
| significant loss of Plexin C1 in metastatic melanoma compared with primary melanoma, suggesting the possibility that the Plexin C1 receptor is a tumor suppressor protein for melanoma | The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis.
Lazova R, Gould Rothberg BE, Rimm D, Scott G. | 01/21/2010 |
| Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression. | Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression.
Scott GA, McClelland LA, Fricke AF, Fender A. | 01/21/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.
Li Y, Rowland C, Xiromerisiou G, Lagier RJ, Schrodi SJ, Dradiotis E, Ross D, Bui N, Catanese J, Aggelakis K, Grupe A, Hadjigeorgiou G., Free PMC Article | 09/24/2008 |
| GTP-bound form of Rab7 promotes melanogenesis through the regulation of gp100 maturation in melanoma cells. | Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins.
Scott GA, McClelland LA, Fricke AF. | 01/21/2010 |