| KIF20A Promotes CRC Progression and the Warburg Effect through the C-Myc/HIF-1alpha Axis. | KIF20A Promotes CRC Progression and the Warburg Effect through the C-Myc/HIF-1α Axis.
Wu M, Wu X, Han J. | 05/30/2024 |
| Circ_0084188 Regulates the progression of colorectal cancer through the miR-769-5p/KIF20A axis. | Circ_0084188 Regulates the progression of colorectal cancer through the miR-769-5p/KIF20A axis.
Zhang L, Song W, Shi J, Chen Y. | 11/6/2023 |
| Grade scoring system reveals distinct molecular subtypes and identifies KIF20A as a novel biomarker for predicting temozolomide treatment efficiency in gliomas. | Grade scoring system reveals distinct molecular subtypes and identifies KIF20A as a novel biomarker for predicting temozolomide treatment efficiency in gliomas.
Ye L, Tong S, Wang Y, Wang Y, Ma W. | 08/20/2023 |
| High expression of KIF20A in bladder cancer as a potential prognostic target for poor survival of renal cell carcinoma. | High expression of KIF20A in bladder cancer as a potential prognostic target for poor survival of renal cell carcinoma.
Liu B, Su J, Fan B, Ni X, Jin T., Free PMC Article | 01/21/2023 |
| KIF20A promotes the development of fibrosarcoma via PI3K-Akt signaling pathway. | KIF20A promotes the development of fibrosarcoma via PI3K-Akt signaling pathway.
Jin Z, Tao S, Zhang C, Xu D, Zhu Z. | 10/8/2022 |
| MKLP2 functions in early mitosis to ensure proper chromosome congression. | MKLP2 functions in early mitosis to ensure proper chromosome congression.
Schrock MS, Scarberry L, Stromberg BR, Sears C, Torres AE, Tallman D, Krupinski L, Chakravarti A, Summers MK., Free PMC Article | 07/2/2022 |
| The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor. | The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor.
Copello VA, Burnstein KL., Free PMC Article | 05/21/2022 |
| Low expression of KIF20A suppresses cell proliferation, promotes chemosensitivity and is associated with better prognosis in HCC. | Low expression of KIF20A suppresses cell proliferation, promotes chemosensitivity and is associated with better prognosis in HCC.
Wu C, Qi X, Qiu Z, Deng G, Zhong L., Free PMC Article | 02/5/2022 |
| The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal. | The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.
Hieda M, Matsumoto T, Isobe M, Kurono S, Yuka K, Kametaka S, Wang JY, Chi YH, Kameda K, Kimura H, Matsuura N, Matsuura S., Free PMC Article | 12/18/2021 |
| MKLP2 Is a Motile Kinesin that Transports the Chromosomal Passenger Complex during Anaphase. | MKLP2 Is a Motile Kinesin that Transports the Chromosomal Passenger Complex during Anaphase.
Adriaans IE, Hooikaas PJ, Aher A, Vromans MJM, van Es RM, Grigoriev I, Akhmanova A, Lens SMA. | 08/14/2021 |
| Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome. | Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome.
Ren X, Chen X, Ji Y, Li L, Li Y, Qin C, Fang K., Free PMC Article | 04/24/2021 |
| Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle. | Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
Serena M, Bastos RN, Elliott PR, Barr FA., Free PMC Article | 03/20/2021 |
| Cyclin F and KIF20A, FOXM1 target genes, increase proliferation and invasion of ovarian cancer cells. | Cyclin F and KIF20A, FOXM1 target genes, increase proliferation and invasion of ovarian cancer cells.
Li Y, Guo H, Wang Z, Bu H, Wang S, Wang H, Fang H, Liu Z, Kong B. | 03/6/2021 |
| Characterization of KIF20A as a prognostic biomarker and therapeutic target for different subtypes of breast cancer. | Characterization of KIF20A as a prognostic biomarker and therapeutic target for different subtypes of breast cancer.
Nakamura M, Takano A, Thang PM, Tsevegjav B, Zhu M, Yokose T, Yamashita T, Miyagi Y, Daigo Y. | 02/13/2021 |
| KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway. | KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway.
Xiong M, Zhuang K, Luo Y, Lai Q, Luo X, Fang Y, Zhang Y, Li A, Liu S., Free PMC Article | 10/31/2020 |
| Bladder urothelial cells soften with an increasing cancer grade. Inhibiting KIF20A makes the intracellular environment softer for both high- and low-grade bladder cancer cells. Upon inhibition of KIF20A, cortical stiffness also decreases in lower grade cells, while it surprisingly increases in higher grade malignant cells. | Role of a Kinesin Motor in Cancer Cell Mechanics.
Mandal K, Pogoda K, Nandi S, Mathieu S, Kasri A, Klein E, Radvanyi F, Goud B, Janmey PA, Manneville JB., Free PMC Article | 08/1/2020 |
| a novel circ_0005576/miR-153-3p/KIF20A axis promoting cervical cancer progression, is reported. | Upregulated circ_0005576 facilitates cervical cancer progression via the miR-153/KIF20A axis.
Ma H, Tian T, Liu X, Xia M, Chen C, Mai L, Xie S, Yu L. | 02/15/2020 |
| our study demonstrated that KIF20A might confer malignant phenotype to LUAD by regulating cell proliferation and apoptosis, providing a new potential biomarker for clinical treatment of LUAD. | Overexpression of KIF20A confers malignant phenotype of lung adenocarcinoma by promoting cell proliferation and inhibiting apoptosis.
Zhao X, Zhou LL, Li X, Ni J, Chen P, Ma R, Wu J, Feng J., Free PMC Article | 11/16/2019 |
| KIF20A promotes the proliferation and metastasis of bladder cancer cells. Bladder cancer patients with a high KIF20A expression have a worse tumour differentiation and a poor prognosis. | KIF20A Affects the Prognosis of Bladder Cancer by Promoting the Proliferation and Metastasis of Bladder Cancer Cells.
Shen T, Yang L, Zhang Z, Yu J, Dai L, Gao M, Shang Z, Niu Y., Free PMC Article | 08/31/2019 |
| High expression of KIF20A is associated with recurrence in pancreatic cancer. | Aberrant KIF20A expression might independently predict poor overall survival and recurrence-free survival of hepatocellular carcinoma.
Lu M, Huang X, Chen Y, Fu Y, Xu C, Xiang W, Li C, Zhang S, Yu C. | 07/27/2019 |
| KIF20A-knockdown exhibits a suppressive effect on the cell cycle and has an inhibitory effect on the terminal cell division process (cytokinesis) leading to partial multinuclearity of the cells. | KIF20A, highly expressed in immature hematopoietic cells, supports the growth of HL60 cell line.
Morita H, Matsuoka A, Kida JI, Tabata H, Tohyama K, Tohyama Y. | 12/22/2018 |
| In conclusion, our findings indicated that FOXM1 was highly expressed in lung cancer cells after exposure to ionizing radiation (IR). We also found that FOXM1 promoted radioresistance, invasion, migration, and EMT of lung cancer cells after IR, partly through upregulating KIF20A. | FOXM1 regulates radiosensitivity of lung cancer cell partly by upregulating KIF20A.
Xiu G, Sui X, Wang Y, Zhang Z. | 11/3/2018 |
| Although the present study was preliminary, these data indicate the possible involvement of KIF20A in the proliferation of clearcell carcinoma (CCC), suggesting that targeting this molecule may contribute to reversing the malignant potential consequently affecting the oncologic outcome of CCC patients. | KIF20A expression as a prognostic indicator and its possible involvement in the proliferation of ovarian clear‑cell carcinoma cells.
Kawai Y, Shibata K, Sakata J, Suzuki S, Utsumi F, Niimi K, Sekiya R, Senga T, Kikkawa F, Kajiyama H., Free PMC Article | 10/13/2018 |
| Results suggest that coupling between actin and microtubule cytoskeletons driven by Myosin II and KIF20A ensures the spatial coordination between RAB6-positive vesicles fission from Golgi/trans-Golgi network membranes and their exit along microtubules. | Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions.
Miserey-Lenkei S, Bousquet H, Pylypenko O, Bardin S, Dimitrov A, Bressanelli G, Bonifay R, Fraisier V, Guillou C, Bougeret C, Houdusse A, Echard A, Goud B., Free PMC Article | 10/6/2018 |
| Study reveals the mechanism controlling abscission through integration of Aurora B kinase and B56-bound PP2A phosphatase activities on the kinesin motor protein MKlp2. MKlp2 is an essential protein for promoting abscission, which may regulate tethering and stabilizing of the PM to the microtubule cytoskeleton at the intercellular bridge through its previously uncharacterized lipid association motif. | Opposing Activities of Aurora B Kinase and B56-PP2A Phosphatase on MKlp2 Determine Abscission Timing.
Fung SYS, Kitagawa M, Liao PJ, Wong J, Lee SH. | 07/21/2018 |