| METTL14-mediated upregulation of lncRNA HOTAIR represses PP1alpha expression by promoting H3K4me1 demethylation in oxycodone-treated mice. | METTL14-mediated upregulation of lncRNA HOTAIR represses PP1α expression by promoting H3K4me1 demethylation in oxycodone-treated mice.
Liu TC, Li HX, Wan YX, Shi G, Zhao YP, Liu YF, Fan XY., Free PMC Article | 07/25/2024 |
| Dynamic regulation of BDNF gene expression by estradiol and lncRNA HOTAIR. | Dynamic regulation of BDNF gene expression by estradiol and lncRNA HOTAIR.
Deb P, Chini A, Guha P, Rishi A, Bhan A, Brady B, Perrotti LI, Mandal SS. | 01/29/2024 |
| Mechanism of lncRNA HOTAIR in attenuating cardiomyocyte pyroptosis in mice with heart failure via the miR-17-5p/RORA axis. | Mechanism of lncRNA HOTAIR in attenuating cardiomyocyte pyroptosis in mice with heart failure via the miR-17-5p/RORA axis.
He L, Lu F, Zhang F, Fan S, Xu J. | 12/26/2023 |
| HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation. | HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation.
Li Y, Sun W, Li J, Du R, Xing W, Yuan X, Zhong G, Zhao D, Liu Z, Jin X, Pan J, Li Y, Li Q, Kan G, Han X, Ling S, Sun X, Li Y., Free PMC Article | 11/1/2023 |
| Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD. | Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Dai Z, Liu X, Zeng H, Chen Y., Free PMC Article | 12/24/2022 |
| LncRNA HOTAIR promotes myocardial fibrosis in atrial fibrillation through binding with PTBP1 to increase the stability of Wnt5a. | LncRNA HOTAIR promotes myocardial fibrosis in atrial fibrillation through binding with PTBP1 to increase the stability of Wnt5a.
Tan W, Wang K, Yang X, Wang K, Wang N, Jiang TB. | 10/22/2022 |
| Ghrelin Relieves Obesity-Induced Myocardial Injury by Regulating the Epigenetic Suppression of miR-196b Mediated by lncRNA HOTAIR. | Ghrelin Relieves Obesity-Induced Myocardial Injury by Regulating the Epigenetic Suppression of miR-196b Mediated by lncRNA HOTAIR.
Lang YY, Xu XY, Liu YL, Ye CF, Hu N, Yao Q, Cheng WS, Cheng ZG, Liu Y., Free PMC Article | 08/13/2022 |
| LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression. | LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.
Kong X, Fei Q, Pan C, Jin J, Zheng J, Wu D, Li H, Huang X. | 05/14/2022 |
| The Involvement of lncRNA HOTAIR/miR-130a-3p Axis in the Regulation of Voluntary Exercise on Cognition and Inflammation of Alzheimer's Disease. | The Involvement of lncRNA HOTAIR/miR-130a-3p Axis in the Regulation of Voluntary Exercise on Cognition and Inflammation of Alzheimer's Disease.
Lu J, Liu L, Chen J, Zhi J, Li J, Li L, Jiang Z., Free PMC Article | 04/30/2022 |
| LncRNA HOX transcript antisense RNA mitigates cardiac function injury in chronic heart failure via regulating microRNA-30a-5p to target KDM3A. | LncRNA HOX transcript antisense RNA mitigates cardiac function injury in chronic heart failure via regulating microRNA-30a-5p to target KDM3A.
Zhang X, Gao Y, Wu H, Mao Y, Qi Y., Free PMC Article | 04/30/2022 |
| LncRNA HOTAIR regulates the lipid accumulation in non-alcoholic fatty liver disease via miR-130b-3p/ROCK1 axis. | LncRNA HOTAIR regulates the lipid accumulation in non-alcoholic fatty liver disease via miR-130b-3p/ROCK1 axis.
Guo B, Cheng Y, Yao L, Zhang J, Lu J, Qi H, Chen H. | 04/9/2022 |
| The lncRNA HOTAIR regulates autophagy and affects lipopolysaccharide-induced acute lung injury through the miR-17-5p/ATG2/ATG7/ATG16 axis. | The lncRNA HOTAIR regulates autophagy and affects lipopolysaccharide-induced acute lung injury through the miR-17-5p/ATG2/ATG7/ATG16 axis.
Li Y, Liang Z, He H, Huang X, Mo Z, Tan J, Guo W, Zhao Z, Wei S., Free PMC Article | 02/19/2022 |
| LncRNA HOTAIR Promotes Neuronal Damage Through Facilitating NLRP3 Mediated-Pyroptosis Activation in Parkinson's Disease via Regulation of miR-326/ELAVL1 Axis. | LncRNA HOTAIR Promotes Neuronal Damage Through Facilitating NLRP3 Mediated-Pyroptosis Activation in Parkinson's Disease via Regulation of miR-326/ELAVL1 Axis.
Zhang Q, Huang XM, Liao JX, Dong YK, Zhu JL, He CC, Huang J, Tang YW, Wu D, Tian JY. | 02/5/2022 |
| LncRNA HOTAIR Promotes LPS-Induced Inflammation and Apoptosis of Cardiomyocytes via Lin28-Mediated PDCD4 Stability. | LncRNA HOTAIR Promotes LPS-Induced Inflammation and Apoptosis of Cardiomyocytes via Lin28-Mediated PDCD4 Stability.
Ni SY, Xu WT, Liao GY, Wang YL, Li J. | 12/25/2021 |
| Downregulation of Hotair or LSD1 Impaired Heart Regeneration in the Neonatal Mouse. | Downregulation of Hotair or LSD1 Impaired Heart Regeneration in the Neonatal Mouse.
Fei Q, Qiu M, Fan G, Zhang B, Wang Q, Zhang S, Wang S, Yang B, Zhang L. | 09/25/2021 |
| LncRNA HOTAIR Participates in Microglia Activation and Inflammatory Factor Release by Regulating the Ubiquitination of MYD88 in Traumatic Brain Injury. | LncRNA HOTAIR Participates in Microglia Activation and Inflammatory Factor Release by Regulating the Ubiquitination of MYD88 in Traumatic Brain Injury.
Cheng S, Zhang Y, Chen S, Zhou Y. | 08/28/2021 |
| Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced osteogenic differentiation by targeting the proliferation of mesenchymal stem cells (MSCs). | Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced osteogenic differentiation by targeting the proliferation of mesenchymal stem cells (MSCs).
Li R, Zhang W, Yan Z, Liu W, Fan J, Feng Y, Zeng Z, Cao D, Haydon RC, Luu HH, Deng ZL, He TC, Zou Y., Free PMC Article | 08/21/2021 |
| LncRNA HOTAIR regulates glucose transporter Glut1 expression and glucose uptake in macrophages during inflammation. | LncRNA HOTAIR regulates glucose transporter Glut1 expression and glucose uptake in macrophages during inflammation.
Obaid M, Udden SMN, Alluri P, Mandal SS., Free PMC Article | 08/14/2021 |
| LncRNA HOTAIR aggravates myocardial ischemia-reperfusion injury by sponging microRNA-126 to upregulate SRSF1. | LncRNA HOTAIR aggravates myocardial ischemia-reperfusion injury by sponging microRNA-126 to upregulate SRSF1.
Sun Y, Hu ZQ. | 05/22/2021 |
| Long noncoding RNA HOTAIR promotes burn wound healing by regulating epidermal stem cells. | Long non‑coding RNA HOTAIR promotes burn wound healing by regulating epidermal stem cells.
Shi Y, Yang R, Tu L, Liu D., Free PMC Article | 04/24/2021 |
| Long non-coding RNA HOTAIR knockdown enhances radiosensitivity through regulating microRNA-93/ATG12 axis in colorectal cancer. | Long non-coding RNA HOTAIR knockdown enhances radiosensitivity through regulating microRNA-93/ATG12 axis in colorectal cancer.
Liu Y, Chen X, Chen X, Liu J, Gu H, Fan R, Ge H., Free PMC Article | 04/13/2021 |
| Long noncoding RNA Hotair facilitates retinal endothelial cell dysfunction in diabetic retinopathy. | Long noncoding RNA Hotair facilitates retinal endothelial cell dysfunction in diabetic retinopathy.
Zhao D, Zhao Y, Wang J, Wu L, Liu Y, Zhao S, Guo F, Ma X, Zhang H, Li Z, Meng D, Xu L, Zhang L, Liu J, Qin G. | 03/28/2021 |
| Silence of HOTAIR inhibits insulin secretion and proliferation in pancreatic beta cells. | Silence of HOTAIR inhibits insulin secretion and proliferation in pancreatic β cells.
Zhu HP. | 02/13/2021 |
| Here hepatocyte nuclear factor 4-alpha (HNF4alpha), as inducer of epithelial differentiation, was demonstrated to directly repress HOTAIR transcription in the mesenchymal-to epithelial transition. Mechanistically, HNF4alpha was found to cause the release of a chromatin loop on HOTAIR regulatory elements thus exerting an enhancer-blocking activity. | The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation.
Battistelli C, Sabarese G, Santangelo L, Montaldo C, Gonzalez FJ, Tripodi M, Cicchini C., Free PMC Article | 07/11/2020 |
| HOTAIR lncRNA dysregulation may be a bystander in diabetic kidney disease without necessarily contributing to the pathogenesis of the condition in humans and in a mouse model | Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease.
Majumder S, Hadden MJ, Thieme K, Batchu SN, Niveditha D, Chowdhury S, Yerra VG, Advani SL, Bowskill BB, Liu Y, Vakili H, Alghamdi TA, White KE, Geldenhuys L, Siddiqi FS, Advani A. | 07/11/2020 |