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    HOTTIP HOXA distal transcript antisense RNA [ Homo sapiens (human) ]

    Gene ID: 100316868, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association of Genetic Polymorphisms in Long Noncoding RNA HOTTIP with Risk of Idiopathic Recurrent Spontaneous Abortion.

    Association of Genetic Polymorphisms in Long Noncoding RNA HOTTIP with Risk of Idiopathic Recurrent Spontaneous Abortion.
    Mirinejad S, Salimi S, Sargazi S, Heidari Nia M, Sheervalilou R, Majidpour M, Harati-Sadegh M, Sarhadi M, Shahraki S, Ghasemi M.

    09/9/2024
    Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-506 pathway.

    Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-506 pathway.
    Zhang C, Hu Z, Fu Y, Wang J., Free PMC Article

    08/30/2024
    A coordinated function of lncRNA HOTTIP and miRNA-196b underpinning leukemogenesis by targeting FAS signaling.

    A coordinated function of lncRNA HOTTIP and miRNA-196b underpinning leukemogenesis by targeting FAS signaling.
    Singh AP, Luo H, Matur M, Eshelman MA, Hamamoto K, Sharma A, Lesperance J, Huang S., Free PMC Article

    08/8/2024
    Long non-coding RNA HOTTIP exerts an oncogenic function by regulating HOXA13 in nasopharyngeal carcinoma.

    Long non-coding RNA HOTTIP exerts an oncogenic function by regulating HOXA13 in nasopharyngeal carcinoma.
    Feng H, Zhao F, Luo J, Xu S, Liang Z, Xu W, Bao Y, Qin G., Free PMC Article

    08/3/2023
    LncRNA HOTTIP promotes inflammatory response in acute gouty arthritis via miR-101-3p/BRD4 axis.

    LncRNA HOTTIP promotes inflammatory response in acute gouty arthritis via miR-101-3p/BRD4 axis.
    Shao P, Liu H, Xue Y, Xiang T, Sun Z.

    02/4/2023
    A Computationally Constructed lncRNA-Associated Competing Triplet Network in Clear Cell Renal Cell Carcinoma.

    A Computationally Constructed lncRNA-Associated Competing Triplet Network in Clear Cell Renal Cell Carcinoma.
    Zhang H, Ye Q, Chen Z, Zhao C, Wu Q, Ding Y, Shao Q, Zhao Y., Free PMC Article

    12/10/2022
    Long Non-Coding RNA HOTTIP is Elevated in Patients with Sepsis and Promotes Cardiac Dysfunction.

    Long Non-Coding RNA HOTTIP is Elevated in Patients with Sepsis and Promotes Cardiac Dysfunction.
    Fan H, Shao H, Gao X.

    10/8/2022
    LncRNA HOTTIP facilitates osteogenic differentiation in bone marrow mesenchymal stem cells and induces angiogenesis via interacting with TAF15 to stabilize DLX2.

    LncRNA HOTTIP facilitates osteogenic differentiation in bone marrow mesenchymal stem cells and induces angiogenesis via interacting with TAF15 to stabilize DLX2.
    Zeng X, Dong Q, Liu Q, Tan WJ, Liu XD.

    06/25/2022
    M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-kappaB pathway.

    M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway.
    Jiang H, Zhou L, Shen N, Ning X, Wu D, Jiang K, Huang X., Free PMC Article

    04/16/2022
    Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1alpha/VEGF signaling.

    Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling.
    Wei H, Xu Z, Chen L, Wei Q, Huang Z, Liu G, Li W, Wang J, Tang Q, Pu J., Free PMC Article

    03/26/2022
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia.

    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia.
    Luo H, Zhu G, Eshelman MA, Fung TK, Lai Q, Wang F, Zeisig BB, Lesperance J, Ma X, Chen S, Cesari N, Cogle C, Chen B, Xu B, Yang FC, So CWE, Qiu Y, Xu M, Huang S., Free PMC Article

    03/5/2022
    HOTTIP is upregulated in esophageal cancer and triggers the drug resistance.

    HOTTIP is upregulated in esophageal cancer and triggers the drug resistance.
    Li Y, Liu Y, Chen G, Liu H, Wu Y, Liu J, Zhang Z.

    12/11/2021
    LncRNA HOTTIP inhibits cell pyroptosis by targeting miR-148a-3p/AKT2 axis in ovarian cancer.

    LncRNA HOTTIP inhibits cell pyroptosis by targeting miR-148a-3p/AKT2 axis in ovarian cancer.
    Tan C, Liu W, Zheng ZH, Wan XG.

    12/11/2021
    Long noncoding RNA HOTTIP enhances the fibrosis of lung tissues by regulating the miR7445p/PTBP1 signaling axis.

    Long non‑coding RNA HOTTIP enhances the fibrosis of lung tissues by regulating the miR‑744‑5p/PTBP1 signaling axis.
    Li J, Chai W, Zhao Z, Zhou Y, Wu Q., Free PMC Article

    12/4/2021
    LncRNA HOTTIP facilitates cell proliferation, invasion, and migration in osteosarcoma by interaction with PTBP1 to promote KHSRP level.

    LncRNA HOTTIP facilitates cell proliferation, invasion, and migration in osteosarcoma by interaction with PTBP1 to promote KHSRP level.
    Yao XY, Liu JF, Luo Y, Xu XZ, Bu J., Free PMC Article

    12/4/2021
    Knockdown of lncRNA HOTTIP Inhibits Retinoblastoma Progression by Modulating the miR-101-3p/STC1 Axis.

    Knockdown of lncRNA HOTTIP Inhibits Retinoblastoma Progression by Modulating the miR-101-3p/STC1 Axis.
    Yuan X, Sun Z, Cui C., Free PMC Article

    11/13/2021
    Long noncoding RNA HOTTIP promotes the metastatic potential of ovarian cancer through the regulation of the miR-615-3p/SMARCE1 pathway.

    Long noncoding RNA HOTTIP promotes the metastatic potential of ovarian cancer through the regulation of the miR-615-3p/SMARCE1 pathway.
    Wu H, Wei HY, Chen QQ.

    10/9/2021
    The Influence of rs1859168 Polymorphism on Serum Expression of HOTTIP and Its Target miR-615-3p in Egyptian Patients with Breast Cancer.

    The Influence of rs1859168 Polymorphism on Serum Expression of HOTTIP and Its Target miR-615-3p in Egyptian Patients with Breast Cancer.
    Abdelaleem OO, Shaker OG, AbdelHafez MN, Abdelghaffar NK, Eid HM, Zaidan M, Khalefa AA, Ahmed NA, Hemeda NF, Zaki OM, Awaji AAA, Mohammed SR., Free PMC Article

    10/9/2021
    Deregulation of long noncoding RNAs ANCR, TINCR, HOTTIP and SPRY4-IT1 in plasma of systemic sclerosis patients: SPRY4-IT1 as a novel biomarker of scleroderma and its subtypes.

    Deregulation of long noncoding RNAs ANCR, TINCR, HOTTIP and SPRY4-IT1 in plasma of systemic sclerosis patients: SPRY4-IT1 as a novel biomarker of scleroderma and its subtypes.
    Abd-Elmawla MA, Hassan M, Elsabagh YA, Alnaggar ARLR, Senousy MA.

    10/9/2021
    Association Between rs1859168/HOTTIP Expression Level and Colorectal Cancer and Adenomatous Polyposis Risk in Egyptians.

    Association Between rs1859168/HOTTIP Expression Level and Colorectal Cancer and Adenomatous Polyposis Risk in Egyptians.
    Ali MA, Shaker OG, Ezzat EM, Gaber SN, Hassan EA, Abdelwahed MY, AbdelHafez MN, Khalil MAF, Abouelseoud S.

    07/17/2021
    Downregulation of lncRNA HOTTIP Suppresses the Proliferation, Migration, and Invasion of Oral Tongue Squamous Cell Carcinoma by Regulation of HMGA2-Mediated Wnt/beta-Catenin Pathway.

    Downregulation of lncRNA HOTTIP Suppresses the Proliferation, Migration, and Invasion of Oral Tongue Squamous Cell Carcinoma by Regulation of HMGA2-Mediated Wnt/β-Catenin Pathway.
    Xiong L, Tang Y, Tang J, Liu Z, Wang X.

    07/17/2021
    LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis.

    LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis.
    He X, Gao K, Lu S, Wu R., Free PMC Article

    07/10/2021
    LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway.

    LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway.
    Liu J, Hu HB, Liu YM, Li FX, Zhang LP, Liao ZM., Free PMC Article

    05/8/2021
    Inhibition of lncRNA HOTTIP ameliorated myofibroblast activities and inflammatory cytokines in oral submucous fibrosis.

    Inhibition of lncRNA HOTTIP ameliorated myofibroblast activities and inflammatory cytokines in oral submucous fibrosis.
    Lee YH, Yu CC, Hsieh PL, Liao YW, Yu CH, Su TR.

    05/1/2021
    LncRNA HOTTIP facilitates the stemness of breast cancer via regulation of miR-148a-3p/WNT1 pathway.

    LncRNA HOTTIP facilitates the stemness of breast cancer via regulation of miR-148a-3p/WNT1 pathway.
    Han L, Yan Y, Zhao L, Liu Y, Lv X, Zhang L, Zhao Y, Zhao H, He M, Wei M., Free PMC Article

    05/1/2021
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