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    MIR1246 microRNA 1246 [ Homo sapiens (human) ]

    Gene ID: 100302142, updated on 17-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    5'-Isoforms of miR-1246 Have Distinct Targets and Stronger Functional Impact Compared with Canonical miR-1246 in Colorectal Cancer Cells In Vitro.

    5'-Isoforms of miR-1246 Have Distinct Targets and Stronger Functional Impact Compared with Canonical miR-1246 in Colorectal Cancer Cells In Vitro.
    Lukosevicius R, Alzbutas G, Varkalaite G, Salteniene V, Tilinde D, Juzenas S, Kulokiene U, Janciauskas D, Poskiene L, Adamonis K, Kiudelis G, Kupcinskas J, Skieceviciene J., Free PMC Article

    03/14/2024
    Exploring miR-155-5p and miR-1246 as Diagnostic and Prognostic Markers in Oral Squamous cell carcinoma.

    Exploring miR-155-5p and miR-1246 as Diagnostic and Prognostic Markers in Oral Squamous cell carcinoma.
    Maheswari R, Urs AB, Kumar P, Koner BC, Guru SA, Rawat G.

    02/26/2024
    Aseptic loosening around total joint replacement in humans is regulated by miR-1246 and miR-6089 via the Wnt signalling pathway.

    Aseptic loosening around total joint replacement in humans is regulated by miR-1246 and miR-6089 via the Wnt signalling pathway.
    Deng Y, Phillips K, Feng ZP, Smith PN, Li RW., Free PMC Article

    02/8/2024
    MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.

    MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
    Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P., Free PMC Article

    12/6/2023
    Identification of serum miR-1246 and miR-150-5p as novel diagnostic biomarkers for high-grade serous ovarian cancer.

    Identification of serum miR-1246 and miR-150-5p as novel diagnostic biomarkers for high-grade serous ovarian cancer.
    Niemira M, Erol A, Bielska A, Zeller A, Skwarska A, Chwialkowska K, Kuzmicki M, Szamatowicz J, Reszec J, Knapp P, Moniuszko M, Kretowski A., Free PMC Article

    11/14/2023
    CADM1 impairs the effect of miR-1246 on promoting cell cycle progression in chemo-resistant leukemia cells.

    CADM1 impairs the effect of miR-1246 on promoting cell cycle progression in chemo-resistant leukemia cells.
    Xie B, Zhao L, Zhang Z, Zhou C, Tian Y, Kang Y, Chen J, Wei H, Li L., Free PMC Article

    11/2/2023
    Human bone marrow mesenchymal stem cell-derived extracellular vesicles restore Th17/Treg homeostasis in periodontitis via miR-1246.

    Human bone marrow mesenchymal stem cell-derived extracellular vesicles restore Th17/Treg homeostasis in periodontitis via miR-1246.
    Xia Y, Cheng T, Zhang C, Zhou M, Hu Z, Kang F, Liao C.

    10/11/2023
    Vascular endothelial cell-derived exosomal miR-1246 facilitates posterior capsule opacification development by targeting GSK-3beta in diabetes mellitus.

    Vascular endothelial cell-derived exosomal miR-1246 facilitates posterior capsule opacification development by targeting GSK-3β in diabetes mellitus.
    Guo C, Zhang J, Wang J, Su L, Ning X, Guo Y, Han J, Ma N.

    05/23/2023
    The Diagnostic Power of Circulating miR-1246 in Screening Cancer: An Updated Meta-analysis.

    The Diagnostic Power of Circulating miR-1246 in Screening Cancer: An Updated Meta-analysis.
    Huynh KQ, Le AT, Phan TT, Ho TT, Pho SP, Nguyen HT, Le BT, Nguyen TT, Nguyen ST., Free PMC Article

    05/15/2023
    In silico and in vitro analysis of the impact of single substitutions within EXO-motifs on Hsa-MiR-1246 intercellular transfer in breast cancer cell.

    In silico and in vitro analysis of the impact of single substitutions within EXO-motifs on Hsa-MiR-1246 intercellular transfer in breast cancer cell.
    Rybarczyk A, Lehmann T, Iwańczyk-Skalska E, Juzwa W, Pławski A, Kopciuch K, Blazewicz J, Jagodziński PP., Free PMC Article

    01/21/2023
    miR-1246-overexpressing exosomes suppress UVB-induced photoaging via regulation of TGF-beta/Smad and attenuation of MAPK/AP-1 pathway.

    miR-1246-overexpressing exosomes suppress UVB-induced photoaging via regulation of TGF-β/Smad and attenuation of MAPK/AP-1 pathway.
    Gao W, Yuan LM, Zhang Y, Huang FZ, Gao F, Li J, Xu F, Wang H, Wang YS.

    01/14/2023
    Circulating serum miR-1246 and miR-1229 as diagnostic biomarkers in colorectal carcinoma.

    Circulating serum miR-1246 and miR-1229 as diagnostic biomarkers in colorectal carcinoma.
    Rafiee R, Razmara E, Motavaf M, Mossahebi-Mohammadi M, Khajehsharifi S, Rouhollah F, Babashah S.

    12/24/2022
    Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus.

    Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus.
    Zhang Q, Liu Y, Liao J, Wu R, Zhan Y, Zhang P, Luo S., Free PMC Article

    10/15/2022
    MiR-1246 is responsible for lung cancer cells-derived exosomes-mediated promoting effects on lung cancer stemness via targeting TRIM17.

    MiR-1246 is responsible for lung cancer cells-derived exosomes-mediated promoting effects on lung cancer stemness via targeting TRIM17.
    Liu Z, Zhao W, Yang R.

    10/15/2022
    miR-1246 Promotes Laryngeal Squamous Cell Carcinoma Progression by Interacting with THBS1.

    miR-1246 Promotes Laryngeal Squamous Cell Carcinoma Progression by Interacting with THBS1.
    Wu L, Zuo N, Pan S, Wang Y, Wang Q, Ma J.

    08/27/2022
    The diagnostic and prognostic values of circulating miRNA-1246 in multiple myeloma.

    The diagnostic and prognostic values of circulating miRNA-1246 in multiple myeloma.
    Zhao G, Jing X, Li Z, Wu X, Gao Z, Ma R.

    07/16/2022
    Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells.

    Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells.
    Qiu W, Guo X, Li B, Wang J, Qi Y, Chen Z, Zhao R, Deng L, Qian M, Wang S, Zhang Z, Guo Q, Zhang S, Pan Z, Zhao S, Xue H, Li G., Free PMC Article

    04/16/2022
    MicroRNA-1246 suppresses the metastasis of breast cancer cells by targeting the DYRK1A/PGRN axis to prevent the epithelial-mesenchymal transition.

    MicroRNA-1246 suppresses the metastasis of breast cancer cells by targeting the DYRK1A/PGRN axis to prevent the epithelial-mesenchymal transition.
    Wang P, Chen W, Zhang Y, Zhong Q, Li Z, Wang Y.

    04/9/2022
    Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246.

    Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246.
    Liu P, Zhang Q, Mi J, Wang S, Xu Q, Zhuang D, Chen W, Liu C, Zhang L, Guo J, Wu X., Free PMC Article

    04/2/2022
    MiR-1246 regulates the PI3K/AKT signaling pathway by targeting PIK3AP1 and inhibits thyroid cancer cell proliferation and tumor growth.

    MiR-1246 regulates the PI3K/AKT signaling pathway by targeting PIK3AP1 and inhibits thyroid cancer cell proliferation and tumor growth.
    Li J, Zhang Z, Hu J, Wan X, Huang W, Zhang H, Jiang N., Free PMC Article

    03/26/2022
    miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR.

    miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR.
    Lukosevicius R, Juzenas S, Salteniene V, Kulokiene U, Arstikyte J, Hemmrich-Stanisak G, Franke A, Link A, Ruzgys P, Satkauskas S, Pauzas H, Latkauskas T, Kiudelis G, Balaguer F, Kupcinskas J, Skieceviciene J., Free PMC Article

    03/19/2022
    Silencing of miR-1246 Induces Cell Cycle Arrest and Apoptosis in Cisplatin-Resistant Ovarian Cancer Cells by Promoting ZNF23 Transcription.

    Silencing of miR-1246 Induces Cell Cycle Arrest and Apoptosis in Cisplatin-Resistant Ovarian Cancer Cells by Promoting ZNF23 Transcription.
    Cai L, Zhang Q, Du L, Zheng F.

    03/5/2022
    Exosomal microRNA-1246 from human umbilical cord mesenchymal stem cells potentiates myocardial angiogenesis in chronic heart failure.

    Exosomal microRNA-1246 from human umbilical cord mesenchymal stem cells potentiates myocardial angiogenesis in chronic heart failure.
    Wang Z, Gao D, Wang S, Lin H, Wang Y, Xu W.

    02/19/2022
    MicroRNA-1246 regulates proliferation, invasion, and differentiation in human vascular smooth muscle cells by targeting cystic fibrosis transmembrane conductance regulator (CFTR).

    MicroRNA-1246 regulates proliferation, invasion, and differentiation in human vascular smooth muscle cells by targeting cystic fibrosis transmembrane conductance regulator (CFTR).
    Pan D, Liu G, Li B, Jiang J, Chen W, Li W, Zhang L, Hu Y, Xie S, Yang H.

    12/18/2021
    Comprehensive Analysis of microRNA Profiles in Organoids Derived from Human Colorectal Adenoma and Cancer.

    Comprehensive Analysis of microRNA Profiles in Organoids Derived from Human Colorectal Adenoma and Cancer.
    Nagai H, Kuroha M, Handa T, Karasawa H, Ohnuma S, Naito T, Moroi R, Kanazawa Y, Shiga H, Hamada S, Kakuta Y, Naitoh T, Kinouchi Y, Shimosegawa T, Masamune A.

    11/22/2021
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