| Promoting AMPK/SR-A1-mediated clearance of HMGB1 attenuates chemotherapy-induced peripheral neuropathy. | Promoting AMPK/SR-A1-mediated clearance of HMGB1 attenuates chemotherapy-induced peripheral neuropathy.
Yang X, Jia R, Hu F, Fan W, Lin T, Zhang X, Xu C, Ruan S, Jiang C, Li Y, Pan C, Yang Y, Hu L, Chen Q, Liu WT., Free PMC Article | 05/11/2023 |
| Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity. | Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity.
Kochumon S, Arefanian H, Sindhu S, Thomas R, Jacob T, Al-Sayyar A, Shenouda S, Al-Rashed F, Koistinen HA, Al-Mulla F, Tuomilehto J, Ahmad R., Free PMC Article | 01/14/2023 |
| Steroid Receptor Coactivator-1 (SRC-1) Promoted Cell Metastasis of Gastric Cancer via VEGFC Activator by NF-kappaB. | Steroid Receptor Coactivator-1 (SRC-1) Promoted Cell Metastasis of Gastric Cancer via VEGFC Activator by NF-κB.
Zhao X, You X, Huang C, Liu G, Cheng Z, Zhang H. | 06/18/2022 |
| Ratios of peripheral blood mononuclear cells to lncRNA steroid receptor RNA activator as new indicators of metabolic syndrome. | Ratios of peripheral blood mononuclear cells to lncRNA steroid receptor RNA activator as new indicators of metabolic syndrome.
Zhao L, Liang S, Li C, Yu J, Zou L, Xv W, Qian G, Zhang Y, Huang Y, Li Y, Li Y. | 04/16/2022 |
| Positive association between SRA1 rs801460 variant and proliferative type of benign breast disease with atypia in Ukrainian females. | Positive association between SRA1 rs801460 variant and proliferative type of benign breast disease with atypia in Ukrainian females.
Lukavenko IM, Kolnoguz AV, Levchenko ZM, Harbuzova VY. | 03/19/2022 |
| LncRNA SRA mediates cell migration, invasion, and progression of ovarian cancer via NOTCH signaling and epithelial-mesenchymal transition. | LncRNA SRA mediates cell migration, invasion, and progression of ovarian cancer via NOTCH signaling and epithelial-mesenchymal transition.
Kim LK, Park SA, Yang Y, Kim YT, Heo TH, Kim HJ., Free PMC Article | 02/5/2022 |
| Adipose Tissue Steroid Receptor RNA Activator 1 (SRA1) Expression Is Associated with Obesity, Insulin Resistance, and Inflammation. | Adipose Tissue Steroid Receptor RNA Activator 1 (SRA1) Expression Is Associated with Obesity, Insulin Resistance, and Inflammation.
Kochumon S, Arefanian H, Sindhu S, Shenouda S, Thomas R, Al-Mulla F, Tuomilehto J, Ahmad R., Free PMC Article | 12/18/2021 |
| Steroid receptor RNA activator gene footprint in the progression and drug resistance of colorectal cancer through oxidative phosphorylation pathway. | Steroid receptor RNA activator gene footprint in the progression and drug resistance of colorectal cancer through oxidative phosphorylation pathway.
Mahdevar M, Vatandoost J, Seyed Forootan F, Kiani-Esfahani A, Esmaeili M, Peymani M, Tavakkoli H, Osmay Gure A, Nasr Esfahani MH, Ghaedi K. | 11/22/2021 |
| Long, Noncoding RNA SRA Induces Apoptosis of beta-Cells by Promoting the IRAK1/LDHA/Lactate Pathway. | Long, Noncoding RNA SRA Induces Apoptosis of β-Cells by Promoting the IRAK1/LDHA/Lactate Pathway.
Huang YN, Chiang SL, Lin YJ, Liu SC, Li YH, Liao YC, Lee MR, Su PH, Tsai FJ, Hung HC, Wang CH., Free PMC Article | 09/11/2021 |
| Steroid receptor RNA activator inhibits the migration, invasion and stemness characteristics of renal cell carcinoma cells. | Steroid receptor RNA activator inhibits the migration, invasion and stemness characteristics of renal cell carcinoma cells.
Zhang C, Zhu N, Liu C, Wu H, Yin Y, Shi Y, Liao D, Qin L., Free PMC Article | 07/3/2021 |
| Association between long-chain non-coding RNA SRA1 gene single-nucleotide polymorphism and polycystic ovary syndrome susceptibility. | Association between long-chain non-coding RNA SRA1 gene single-nucleotide polymorphism and polycystic ovary syndrome susceptibility.
Tan J, Hao X, Zhao T, Ying J, Li T, Cheng L., Free PMC Article | 05/29/2021 |
| Steroid receptor RNA activator affects the development of poststroke depression by regulating the peroxisome proliferator-activated receptor gamma signaling pathway. | Steroid receptor RNA activator affects the development of poststroke depression by regulating the peroxisome proliferator-activated receptor γ signaling pathway.
Jiang B, Wang H, Xu H., Free PMC Article | 01/23/2021 |
| long noncoding RNA steroid receptor RNA activator 1 played an antitumor role in osteosarcoma as it reduced cell migration, invasion, and proliferation, but facilitated cell apoptosis via sponging microRNA-208a, which could be regarded as a potential therapeutic target of osteosarcoma treatment. | LncRNA-SRA1 Suppresses Osteosarcoma Cell Proliferation While Promoting Cell Apoptosis.
Guo W, Jiang H, Li H, Li F, Yu Q, Liu Y, Jiang W, Zhang M., Free PMC Article | 12/21/2019 |
| our findings demonstrated that lncRNA SRA is highly correlated with cancer progression and cervical cancer cell proliferation and migration. Furthermore, these results indicate that lncRNA SRA may be a potential therapeutic target and prognostic marker for cervical malignancy. | Long non-coding RNA, steroid receptor RNA activator (SRA), induces tumor proliferation and invasion through the NOTCH pathway in cervical cancer cell lines.
Eoh KJ, Paek J, Kim SW, Kim HJ, Lee HY, Lee SK, Kim YT., Free PMC Article | 07/21/2018 |
| Steroid receptor RNA activator 1-small interfering RNA treatment significantly increased ER-alpha levels but reduced ER-beta levels in endometriotic stromal cells (ESCs). | Silencing of SRA1 Regulates ER Expression and Attenuates the Growth of Stromal Cells in Ovarian Endometriosis.
Lin K, Zhan H, Ma J, Xu K, Wu R, Zhou C, Lin J. | 03/31/2018 |
| These findings suggest that SRA genetic variants may contribute to breast cancer risk | Genetic variants in lncRNA SRA and risk of breast cancer.
Yan R, Wang K, Peng R, Wang S, Cao J, Wang P, Song C., Free PMC Article | 12/9/2017 |
| SRA1 was down expressed in HCC and its level was associated with tumor size and GLU level in patients with HCC for the first time. SRA1 may be a helpful biomarker to diagnostic HCC. | Decreased expression of LncRNA SRA1 in hepatocellular carcinoma and its clinical significance.
Luo P, Jing W, Zhu M, Li ND, Zhou H, Yu MX, Liang CZ, Tu JC. | 04/22/2017 |
| By studying a cohort of idiopathic hypogonadotropic hypogonadism, our findings strongly suggest that SRA1 gene function is required for initiation of puberty in humans | Idiopathic Hypogonadotropic Hypogonadism Caused by Inactivating Mutations in SRA1.
Kotan LD, Cooper C, Darcan Ş, Carr IM, Özen S, Yan Y, Hamedani MK, Gürbüz F, Mengen E, Turan İ, Ulubay A, Akkuş G, Yüksel B, Topaloğlu AK, Leygue E., Free PMC Article | 04/15/2017 |
| Results identified H15-H18 domains in SRA gene playing a key role in regulating ER-mediated transcription. | Truncated SRA RNA derivatives inhibit estrogen receptor-α-mediated transcription.
Jung E, Jang S, Lee J, Kim Y, Shin H, Park HS, Lee Y. | 03/11/2017 |
| REVIEW: Biologic function and role in disease | Steroid receptor RNA activator: Biologic function and role in disease.
Liu C, Wu HT, Zhu N, Shi YN, Liu Z, Ao BX, Liao DF, Zheng XL, Qin L. | 02/18/2017 |
| in human pluripotent stem cells SRA interacts with NANOG and is important for maintenance of the pluripotent state. | Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes.
Wongtrakoongate P, Riddick G, Fucharoen S, Felsenfeld G., Free PMC Article | 07/30/2016 |
| Data suggest that expression of SRA1 (mRNA and protein) is linked to cancer cell motility (invasiveness of breast/cervical tumor cells) and regulation of gene expression. | The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility.
Yan Y, Cooper C, Hamedani MK, Guppy B, Xu W, Tsuyuki D, Zhang C, Nugent Z, Blanchard A, Davie JR, McManus K, Murphy LC, Myal Y, Leygue E. | 05/14/2016 |
| lncRNA SRA expression is potentially associated with PCOS and it has positive correlation with obesity in PCOS, thereby suggesting that elevated lncRNA SRA might be an important mediator in adiposity-related processes in PCOS for susceptible individuals. | Peripheral blood leukocyte expression level of lncRNA steroid receptor RNA activator (SRA) and its association with polycystic ovary syndrome: a case control study.
Liu Z, Hao C, Huang X, Zhang N, Bao H, Qu Q. | 03/12/2016 |
| In endometrioma patients, the surrounding ovarian tissue steroid receptor RNA activator expression is higher compared to controls. | Influence of ovarian endometrioma on expression of steroid receptor RNA activator, estrogen receptors, vascular endothelial growth factor, and thrombospondin 1 in the surrounding ovarian tissues.
Lin K, Ma J, Wu R, Zhou C, Lin J., Free PMC Article | 07/19/2014 |
| NMR spectra of SRA1p in the presence of its 80-nt RNA target indicate that this protein must be part of a multi-protein complex in order to recognize its proposed RNA recognition element. | The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region.
Bilinovich SM, Davis CM, Morris DL, Ray LA, Prokop JW, Buchan GJ, Leeper TC. | 06/14/2014 |