| MiR-290 Family Maintains Pluripotency and Self-Renewal by Regulating MAPK Signaling Pathway in Intermediate Pluripotent Stem Cells. | MiR-290 Family Maintains Pluripotency and Self-Renewal by Regulating MAPK Signaling Pathway in Intermediate Pluripotent Stem Cells.
Liu Y, Li X, Ma X, Du Q, Wang J, Yu H., Free PMC Article | 03/14/2024 |
| Since miR-290 cluster miRNAs are the most dominant stem-cell-specific miRNAs, our results revealed an important cause for the absence of Cyclin D1 in mouse embryonic stem cells. | miR-290 contributes to the low abundance of cyclin D1 protein in mouse embryonic stem cells.
Gong Z, Wang D, Zhu S, Xia Y, Fan C, Zhao B, Jin Y. | 05/19/2018 |
| miR-290 cluster has a clear role in the regulation of a network of genes required for placental development, suggesting a central role for these microRNAs in the evolution of placental mammals | The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport.
Paikari A, D Belair C, Saw D, Blelloch R., Free PMC Article | 11/11/2017 |
| miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency. | miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency.
Cao Y, Guo WT, Tian S, He X, Wang XW, Liu X, Gu KL, Ma X, Huang D, Hu L, Cai Y, Zhang H, Wang Y, Gao P., Free PMC Article | 05/9/2015 |
| These findings implicate miRs as intermediaries in aldosterone signaling in principal cells of the distal kidney nephron. | Aldosterone regulates microRNAs in the cortical collecting duct to alter sodium transport.
Edinger RS, Coronnello C, Bodnar AJ, Labarca M, Bhalla V, LaFramboise WA, Benos PV, Ho J, Johnson JP, Butterworth MB., Free PMC Article | 01/10/2015 |
| expression of miR-290 in highly metastatic breast cancer cell lines significantly decreases tumor progression. | Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b.
Goldberger N, Walker RC, Kim CH, Winter S, Hunter KW., Free PMC Article | 06/15/2013 |
| increased expression of miR290-5p and miR292-5p contributes to the induction of kappaGT at the pre-B stage of B cell development | miR290-5p/292-5p activate the immunoglobulin kappa locus in B cell development.
Garcia PB, Cai A, Bates JG, Nolla H, Schlissel MS., Free PMC Article | 02/2/2013 |
| Regardless of the p53 status, the prosenescence role of miR-290 is specific for primary but not for immortal murine fibroblasts. | Immortalized mouse embryo fibroblasts are resistant to miR-290-induced senescence regardless of p53 status.
Rizzo M, Evangelista M, Mariani L, Simili M, Rainaldi G, Pitto L. | 05/5/2012 |
| mir-290-295 plays important roles in embryonic development as indicated by the partially penetrant lethality of mutant embryos. | Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects.
Medeiros LA, Dennis LM, Gill ME, Houbaviy H, Markoulaki S, Fu D, White AC, Kirak O, Sharp PA, Page DC, Jaenisch R., Free PMC Article | 10/29/2011 |
| Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells | Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells.
Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, Hannett N, Sharp PA, Bartel DP, Jaenisch R, Young RA., Free PMC Article | 07/6/2010 |
| Findings show that miR-290 might act as a physiological effector of NCZ induced as well as culture senescence via p16 regulation expanding the role of this miRNA from embryonic stem to differentiated cells. | miR-290 acts as a physiological effector of senescence in mouse embryo fibroblasts.
Pitto L, Rizzo M, Simili M, Colligiani D, Evangelista M, Mercatanti A, Mariani L, Cremisi F, Rainaldi G. | 03/8/2010 |