| AR12286 Alleviates TGF-beta-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery. | AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery.
Cheng WS, Chen CL, Chen JT, Lin LT, Pao SI, Chen YH, Lu DW., Free PMC Article | 03/20/2021 |
| We also found that ADSCs could upregulate the expression of transforming growth factor b1 (TGF-b1) and fibronectin in tissue from animals with a medication history by accelerating gingival healing of the extraction socket. | Adipose-derived stem cells prevent the onset of bisphosphonate-related osteonecrosis of the jaw through transforming growth factor β-1-mediated gingival wound healing.
Zang X, He L, Zhao L, He Y, Xiao E, Zhang Y., Free PMC Article | 06/27/2020 |
| TGFB1overexpressing bone marrowderived mesenchymal stem cells promoted new bone formation in the rabbit femoral defect model. | Role of TGF‑β1 expressed in bone marrow‑derived mesenchymal stem cells in promoting bone formation in a rabbit femoral defect model.
Sun BY, Zhao BX, Zhu JY, Sun ZP, Shi YA, Huang F., Free PMC Article | 10/20/2018 |
| Data indicate that cardiac contractility modulation (CCM) therapy exerted protective effects against myocardial fibrosis potentially by inhibiting TGF-beta1/Smad3 signaling pathway in chronic heart failure . | Cardiac Contractility Modulation Attenuate Myocardial Fibrosis by Inhibiting TGF-β1/Smad3 Signaling Pathway in a Rabbit Model of Chronic Heart Failure.
Zhang F, Dang Y, Li Y, Hao Q, Li R, Qi X. | 02/18/2017 |
| Studied effects of panax notoginseng saponins on the differentiation of mesenchymal stem cells using gene silencing of TGF-B1 signal pathway. | Effects of panax notoginseng saponins on the osteogenic differentiation of rabbit bone mesenchymal stem cells through TGF-β1 signaling pathway.
Wang Y, Huang X, Tang Y, Lin H, Zhou N., Free PMC Article | 02/18/2017 |
| study suggested that TGF-beta1/Smad3/smad7 is a major pathway which plays an important role in the regulation of the IUA and specific inhibitor of Smad3 (SIS3) may provide a new therapeutic strategy for IUA. | Role of Transforming Growth Factor-β1 and Smads Signaling Pathway in Intrauterine Adhesion.
Salma U, Xue M, Ali Sheikh MS, Guan X, Xu B, Zhang A, Huang L, Xu D., Free PMC Article | 12/17/2016 |
| cell therapy promoted TGF-beta1 expression in nucleus pulposus, leading to anti-inflammatory effects via the inhibition of NF-kappaB, and the amelioration of disc degradation. | TGF-βl Suppresses Inflammation in Cell Therapy for Intervertebral Disc Degeneration.
Yang H, Cao C, Wu C, Yuan C, Gu Q, Shi Q, Zou J., Free PMC Article | 08/13/2016 |
| that prenatal tracheal occlusion increases TGF-beta/Rho kinase pathway, myofibroblast differentiation, and matrix deposition in neonatal rabbit and human congenital diaphragmatic hernia lungs | Increased TGF-β: a drawback of tracheal occlusion in human and experimental congenital diaphragmatic hernia?
Vuckovic A, Herber-Jonat S, Flemmer AW, Ruehl IM, Votino C, Segers V, Benachi A, Martinovic J, Nowakowska D, Dzieniecka M, Jani JC. | 07/30/2016 |
| observation. Based on the above results, we conclude that TGF-beta1-immobilized PLGA-gelatin scaffold seeded with ASCs considerably enhances the quality of the tissue-engineered cartilage, therefore, advancing the field of cartilage tissue engineering | Cartilage Regeneration of Adipose-Derived Stem Cells in the TGF-β1-Immobilized PLGA-Gelatin Scaffold.
Yin F, Cai J, Zen W, Wei Y, Zhou W, Yuan F, Singh SR, Wei Y., Free PMC Article | 03/5/2016 |
| Smad7 plays a crucial role in antagonizing epithelial-mesenchymal transition induced by TGFbeta signaling and is a Notch signaling target in limbal epithelial stem cells. | Notch prevents transforming growth factor-beta-assisted epithelial-mesenchymal transition in cultured limbal progenitor cells through the induction of Smad7.
Tsai TH, Sun MH, Ho TC, Ma HI, Liu MY, Tsao YP., Free PMC Article | 10/4/2014 |
| the role of IL-10 in inhibited allograft rejection may be associated with CD4+CD25+ regulatory T cells and IL-10, and may be independent of TGF-b | Effects of recombinant human interleukin-10 on Treg cells, IL-10 and TGF-β in transplantation of rabbit skin.
Liu KS, Fan XQ, Zhang L, Wen QN, Feng JH, Chen FC, Luo JM, Sun WB., Free PMC Article | 08/30/2014 |
| After NOTCH1 knockdown and TGFB1 stimulation, rabbit mesenchymal stem cells expressed higher levels of proteoglycan and collagen II. | TGF-β1 induces a nucleus pulposus-like phenotype in Notch 1 knockdown rabbit bone marrow mesenchymal stem cells.
Morigele M, Shao Z, Zhang Z, Kaige M, Zhang Y, Qiang W, Yang S. | 02/1/2014 |
| Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased transforming growth factor-beta1 signaling. | Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased transforming growth factor-β1 signaling and is abrogated by angiotensin receptor blockade.
Friedberg MK, Cho MY, Li J, Assad RS, Sun M, Rohailla S, Honjo O, Apitz C, Redington AN. | 02/1/2014 |
| TGF-beta1 gene transcription significantly correlates with the surgical vaginal and dermal wound closure rate. | Transforming growth factor β 1 gene expression during vaginal vs cutaneous surgical woundexpression during vaginal vs cutaneous surgical wound healing in the rabbit.
Abramov Y, Hirsch E, Ilievski V, Goldberg RP, Botros SM, Sand PK. | 01/11/2014 |
| A novel peptide, P2K, regulating TGF-beta1 signaling had an anabolic effect on bovine intervertebral disc cells and rabbit degenerated discs. | Anabolic effects of Peniel 2000, a peptide that regulates TGF-β1 signaling on intervertebral disc degeneration.
Kwon YJ, Lee JW, Moon EJ, Chung YG, Kim OS, Kim HJ. | 07/6/2013 |
| Wound closure was significantly protracted (P < 0.02), whereas TGFbeta1 gene expression was significantly increased (P < 0.0001) during the wound healing process in oophorectomised rabbits. | Transforming growth factor beta1 gene expression during vaginal wound healing in a rabbit menopause model.
Abramov Y, Hirsch E, Ilievski V, Goldberg RP, Sand PK. | 02/16/2013 |
| Radix astragali injection inhibits fibroblast proliferation in hypertrophic scars through down-regulating mRNA expression and protein synthesis of TGF-beta and Smad3. | [Effects of radix astragali on expression of transforming growth factor β 1 and Smad 3 signal pathway in hypertrophic scar of rabbit].
Zhang Y, Qiu L, Li MY. | 03/31/2012 |
| Report established neointimal hyperplasia in vein grafts expands via TGF-beta1 (TGFB1)-mediated progressive fibrosis. | Established neointimal hyperplasia in vein grafts expands via TGF-beta-mediated progressive fibrosis.
Jiang Z, Tao M, Omalley KA, Wang D, Ozaki CK, Berceli SA., Free PMC Article | 01/20/2012 |
| Thrombomodulin downregulation in vein gafts is mediated by paracrine release of TGF-beta1 caused by pressure-induced vessel stretch. | Inhibition of transforming growth factor-β restores endothelial thromboresistance in vein grafts.
Kapur NK, Bian C, Lin E, Deming CB, Sperry JL, Hansen BS, Kakouros N, Rade JJ., Free PMC Article | 11/19/2011 |
| Angiotensin-(1-7) attenuates postangioplasty collagen synthesis in rabbits possibly through down-regulating the expression of TGF-beta1 and inhibiting the activation of Smad2 pathway. | [Angiotensin-(1-7) reduced postangioplasty vascular fibrosis in abdominal aorta of rabbits].
Zeng WT, Chen WY, Leng XY, He JG, Ma H. | 10/22/2011 |
| TGF-beta1 may not be the primary mediator of muscle fibrosis in distraction osteogenesis | Distraction osteogenesis-induced muscle fibrosis may not be associated with TGF-β1.
Koplin SA, Su L, Salamat S, Torrealba J, McCarthy J, Mitchell J, Olabisi R, Noonan KJ. | 09/17/2011 |
| Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1, which delays the development of osteoarthritis. | [Effect of glucosamine hydrochloride capsules on articular cartilage of rabbit knee joint in osteoarthritis].
Chen D, Zhang Z, Cao J, Zhang D, Jia B. | 01/15/2011 |
| results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2, and TGFbeta1 | Effects of raised-intensity phonation on inflammatory mediator gene expression in normal rabbit vocal fold.
Swanson ER, Ohno T, Abdollahian D, Garrett CG, Rousseau B., Free PMC Article | 11/13/2010 |
| TGF-beta1 modulates the expression of IGFBP-4 and PAPP-A in cultured periosteal explants. | Transforming growth factor-beta1 modulates insulin-like growth factor binding protein-4 expression and proteolysis in cultured periosteal explants.
Gonzalez C, Auw Yang KG, Schwab JH, Fitzsimmons JS, Reinholz MM, Resch ZT, Bale LK, Clemens VR, Conover CA, O'Driscoll SW, Reinholz GG., Free PMC Article | 08/9/2010 |