A spectrum of AKT3 activating mutations cause focal malformations of cortical development (FMCDs) in cortical organoids. | A spectrum of AKT3 activating mutations cause focal malformations of cortical development (FMCDs) in cortical organoids. Xu Y, Lu R, Li H, Feng W, Zhao R. | 06/28/2024 |
Differential prognostic values of the three AKT isoforms in acute myeloid leukemia. | Differential prognostic values of the three AKT isoforms in acute myeloid leukemia. Corre E, Soum C, Pfeifer R, Bessière C, Dailhau S, Marbœuf C, Meggetto F, Touriol C, Récher C, Bousquet M, Pyronnet S., Free PMC Article | 04/5/2024 |
Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells. | Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells. Jougasaki M, Takenoshita Y, Umebashi K, Yamamoto M, Sudou K, Nakashima H, Sonoda M, Kinjo T., Free PMC Article | 03/13/2024 |
All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines. | All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines. Tian LY, Smit DJ, Popova NV, Horn S, Velasquez LN, Huber S, Jücker M., Free PMC Article | 03/13/2024 |
Mechanism through which the hsa-circ_0000992- hsa- miR- 936-AKT3 regulatory network promotes the PM2.5-induced inflammatory response in human bronchial epithelial cells. | Mechanism through which the hsa-circ_0000992- hsa- miR- 936-AKT3 regulatory network promotes the PM(2.5)-induced inflammatory response in human bronchial epithelial cells. Li JL, Tan Y, Wang QL, Li CX, Hong JC, Wang HJ, Wu Y, Ni C, Peng XW. | 01/29/2024 |
Differential activation of AKT isoforms by growth factors in human myotubes. | Differential activation of AKT isoforms by growth factors in human myotubes. Roberts BM, Geddis AV, Matheny RW Jr., Free PMC Article | 11/13/2023 |
Detecting Low-Variant Allele Frequency Mosaic Pathogenic Variants of NF1, TSC2, and AKT3 Genes from Blood in Patients with Neurodevelopmental Disorders. | Detecting Low-Variant Allele Frequency Mosaic Pathogenic Variants of NF1, TSC2, and AKT3 Genes from Blood in Patients with Neurodevelopmental Disorders. Kim SH, Kwon SS, Park MR, Lee HA, Kim JH, Cha J, Kim S, Baek ST, Kim SH, Lee JS, Kim HD, Choi JR, Lee ST, Kang HC. | 08/3/2023 |
Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis. | Downregulation of circ_0024028 inhibits IL-22-induced keratinocyte proliferation and migration by miR-486-3p/AKT3 axis. Zhang B, Wu S. | 07/25/2023 |
circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in small cell lung cancer. | circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in small cell lung cancer. Tolomeo D, Traversa D, Venuto S, Ebbesen KK, García Rodríguez JL, Tamma G, Ranieri M, Simonetti G, Ghetti M, Paganelli M, Visci G, Liso A, Kok K, Muscarella LA, Fabrizio FP, Frassanito MA, Lamanuzzi A, Saltarella I, Solimando AG, Fatica A, Ianniello Z, Marsano RM, Palazzo A, Azzariti A, Longo V, Tommasi S, Galetta D, Catino A, Zito A, Mazza T, Napoli A, Martinelli G, Kjems J, Kristensen LS, Vacca A, Storlazzi CT. | 05/12/2023 |
Autoantibodies against PIP4K2B and AKT3 Are Associated with Skin and Lung Fibrosis in Patients with Systemic Sclerosis. | Autoantibodies against PIP4K2B and AKT3 Are Associated with Skin and Lung Fibrosis in Patients with Systemic Sclerosis. Geroldinger-Simić M, Bayati S, Pohjanen E, Sepp N, Nilsson P, Pin E., Free PMC Article | 03/31/2023 |
Circ-AKT3 promotes the proliferation and migration of HCC cells via down-regulating microRNA-335 expression. | Circ-AKT3 promotes the proliferation and migration of HCC cells via down-regulating microRNA-335 expression. Dong B, Li H, Wang C, Qian X, Zhang R. | 01/28/2023 |
AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope. | AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope. Wainstein E, Maik-Rachline G, Blenis J, Seger R. | 12/17/2022 |
LncRNA PVT1 regulates biological function of osteoarthritis cells by regulating miR-497/AKT3 axis. | LncRNA PVT1 regulates biological function of osteoarthritis cells by regulating miR-497/AKT3 axis. Xu J, Fang X, Qin L, Wu Q, Zhan X., Free PMC Article | 12/3/2022 |
Cutaneous vascular anomalies associated with a mosaic variant of AKT3: Genetic analysis continues to refine the diagnosis, nomenclature, and classification of vascular anomalies. | Cutaneous vascular anomalies associated with a mosaic variant of AKT3: Genetic analysis continues to refine the diagnosis, nomenclature, and classification of vascular anomalies. Davies OMT, Garzon MC, Frieden IJ, Cottrell CE, Gripp KW, Saneto RP, Shwayder T, Mirzaa GM, Drolet BA., Free PMC Article | 08/27/2022 |
N(6)-methyladenosine-modified long non-coding RNA AGAP2-AS1 promotes psoriasis pathogenesis via miR-424-5p/AKT3 axis. | N(6)-methyladenosine-modified long non-coding RNA AGAP2-AS1 promotes psoriasis pathogenesis via miR-424-5p/AKT3 axis. Xian J, Shang M, Dai Y, Wang Q, Long X, Li J, Cai Y, Xia C, Peng X. | 03/12/2022 |
Hypomethylation-driven AKT Serine/Threonine Kinase 3 promotes testicular germ cell tumors proliferation and negatively correlates to immune infiltration. | Hypomethylation-driven AKT Serine/Threonine Kinase 3 promotes testicular germ cell tumors proliferation and negatively correlates to immune infiltration. Luo Y, Zhou Q, Zhu F, Fan L, Bo H, Wang X., Free PMC Article | 02/19/2022 |
Circ_0016760 accelerates non-small-cell lung cancer progression through miR-646/AKT3 signaling in vivo and in vitro. | Circ_0016760 accelerates non-small-cell lung cancer progression through miR-646/AKT3 signaling in vivo and in vitro. Chen S, Zhou L, Ran R, Huang J, Zheng Y, Xing M, Cai Y., Free PMC Article | 02/5/2022 |
miR-150 and SRPK1 regulate AKT3 expression to participate in LPS-induced inflammatory response. | miR-150 and SRPK1 regulate AKT3 expression to participate in LPS-induced inflammatory response. Yao Y, Wang H, Xi X, Sun W, Ge J, Li P., Free PMC Article | 01/29/2022 |
CircRNA WHSC1 promotes non-small cell lung cancer progression via sponging microRNA-296-3p and up-regulating expression of AKT serine/threonine kinase 3. | CircRNA WHSC1 promotes non-small cell lung cancer progression via sponging microRNA-296-3p and up-regulating expression of AKT serine/threonine kinase 3. Shi F, Yang Q, Shen D, Chen J., Free PMC Article | 01/15/2022 |
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis. | Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis. Wang S, Yi M, Zhang X, Zhang T, Jiang L, Cao L, Zhou Y, Fang X. | 01/8/2022 |
CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer. | CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer. Ding L, Xie Z. | 12/25/2021 |
Long noncoding RNA LINC01224 promotes cell proliferation and inhibits apoptosis by regulating AKT3 expression via targeting miR4855p in endometrial carcinoma. | Long non‑coding RNA LINC01224 promotes cell proliferation and inhibits apoptosis by regulating AKT3 expression via targeting miR‑485‑5p in endometrial carcinoma. Zuo X, Li W, Yan X, Ma T, Ren Y, Hua M, Yang H, Wu H, Zhu H., Free PMC Article | 12/25/2021 |
LncRNA TP73-AS1 promotes oxidized low-density lipoprotein-induced apoptosis of endothelial cells in atherosclerosis by targeting the miR-654-3p/AKT3 axis. | LncRNA TP73-AS1 promotes oxidized low-density lipoprotein-induced apoptosis of endothelial cells in atherosclerosis by targeting the miR-654-3p/AKT3 axis. Ni J, Huang Z, Wang D., Free PMC Article | 12/25/2021 |
CircRNA circTRAF3 promotes nasopharyngeal carcinoma metastasis through targeting miR-203a-3p/AKT3 axis. | CircRNA circTRAF3 promotes nasopharyngeal carcinoma metastasis through targeting miR-203a-3p/AKT3 axis. Fang X, Huang W, Wu P, Zeng J, Li X. | 11/27/2021 |
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFbeta/CTGF Axis. | Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis. Hinz N, Baranowsky A, Horn M, Kriegs M, Sibbertsen F, Smit DJ, Clezardin P, Lange T, Schinke T, Jücker M., Free PMC Article | 10/23/2021 |