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    OCT1 organic cation/carnitine transporter1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843656, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OCT1
    Official Full Name
    organic cation/carnitine transporter1
    Primary source
    TAIR:AT1G73220
    Locus tag
    AT1G73220
    See related
    Araport:AT1G73220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtOCT1; organic cation/carnitine transporter1; T18K17.11; T18K17_11
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    Genomic context

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    See OCT1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (27538190..27540235)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF789) Neighboring gene ncRNA Neighboring gene Nascent polypeptide-associated complex NAC Neighboring gene nucleoporin protein Ndc1-Nup protein Neighboring gene GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural variation in the expression of ORGANIC CATION TRANSPORTER 1 affects root length responses to cadaverine in Arabidopsis. Strohm AK, et al. J Exp Bot, 2015 Feb. PMID 25403917, Free PMC Article
    2. Genome-wide evaluation of histone methylation changes associated with leaf senescence in Arabidopsis. Brusslan JA, et al. PLoS One, 2012. PMID 22427974, Free PMC Article
    3. Disruption of AtOCT1, an organic cation transporter gene, affects root development and carnitine-related responses in Arabidopsis. Lelandais-Brière C, et al. Plant J, 2007 Jul. PMID 17521409
    4. Spermine modulates the expression of two probable polyamine transporter genes and determines growth responses to cadaverine in Arabidopsis. Sagor GH, et al. Plant Cell Rep, 2016 Jun. PMID 26905725
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_105981.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbohydrate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables carnitine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cadaverine transport IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    organic cation/carnitine transporter1
    NP_565059.2
    • organic cation/carnitine transporter1 (1-Oct); FUNCTIONS IN: carnitine transporter activity, carbohydrate transmembrane transporter activity, transporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: organic cation/carnitine transporter 2 (TAIR:AT1G79360.1); Has 16805 Blast hits to 16754 proteins in 1584 species: Archae - 351; Bacteria - 7847; Metazoa - 4511; Fungi - 2312; Plants - 1172; Viruses - 0; Other Eukaryotes - 612 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27538190..27540235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105981.4 → NP_565059.2  organic cation/carnitine transporter1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565059.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LAB6, Q9CAT6
      UniProtKB/TrEMBL
      A0A178WJR7, A0A5S9WTY5, A0A654ENI4
      Conserved Domains (1) summary
      cd17378
      Location:102 → 511
      MFS_OCT_plant; Plant organic cation/carnitine transporters of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CAT6.1

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