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    UKL3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842031, updated on 22-Aug-2024

    Summary

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    Official Symbol
    UKL3
    Primary source
    Araport:AT1G55810
    Locus tag
    AT1G55810
    See related
    TAIR:AT1G55810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20N2.21; F20N2_21; uridine kinase-like 3
    Summary
    One of the homologous genes predicted to encode proteins with UPRT domains (Uracil phosphoribosyltransferase). Five of these genes (At5g40870, At3g27190, At1g55810, At4g26510 and At3g27440) show a high level of identity, and are annotated as also containing a N-terminal uracil kinase (UK) domain. These genes are referred to as UKL1 (UK-like 1), UKL2, UKL3, UKL4 and UKL5, respectively.
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    Genomic context

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    See UKL3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (20860507..20864287)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ferredoxin-fold anticodon-binding domain protein Neighboring gene BolA-like family protein Neighboring gene lysine-specific demethylase, putative (DUF1296) Neighboring gene coiled-coil protein Neighboring gene Sec14p-like phosphatidylinositol transfer family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001333734.1
    NM_001333735.1
    NM_001333736.1
    NM_001333737.1
    NM_104458.4
    NM_202307.3
    NM_202308.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uracil phosphoribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uridine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CTP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in UMP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 

    General protein information

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    Preferred Names
    uridine kinase-like 3
    NP_175977.1
    • uridine kinase-like 3 (UKL3); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 12937 Blast hits to 12923 proteins in 2615 species: Archae - 215; Bacteria - 9909; Metazoa - 552; Fungi - 508; Plants - 588; Viruses - 2; Other Eukaryotes - 1163 (source: NCBI BLink).
    NP_974036.2
    • uridine kinase-like 3 (UKL3); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 12796 Blast hits to 12782 proteins in 2591 species: Archae - 213; Bacteria - 9841; Metazoa - 556; Fungi - 487; Plants - 538; Viruses - 2; Other Eukaryotes - 1159 (source: NCBI BLink).
    NP_974037.1
    • uridine kinase-like 3 (UKL3); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20860507..20864287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202307.3 → NP_974036.2  uridine kinase-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974036.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WDH0
      Conserved Domains (3) summary
      COG0572
      Location:43 → 249
      Udk; Uridine kinase [Nucleotide transport and metabolism]
      cd02023
      Location:46 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:262 → 458
      UPRTase; Uracil phosphoribosyltransferase

    2. NM_202308.2 → NP_974037.1  uridine kinase-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974037.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQ84, Q8VYB2, Q9LG32
      UniProtKB/TrEMBL
      A0A178WDH0
      Conserved Domains (3) summary
      COG0572
      Location:43 → 249
      Udk; Uridine kinase [Nucleotide transport and metabolism]
      cd02023
      Location:46 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:262 → 463
      UPRTase; Uracil phosphoribosyltransferase

    3. NM_104458.4 → NP_175977.1  uridine kinase-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175977.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQ84, Q8VYB2, Q9LG32
      UniProtKB/TrEMBL
      A0A178WDH0
      Conserved Domains (3) summary
      COG0572
      Location:43 → 249
      Udk; Uridine kinase [Nucleotide transport and metabolism]
      cd02023
      Location:46 → 244
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:262 → 463
      UPRTase; Uracil phosphoribosyltransferase

    4. NM_001333734.1 → NP_001323276.1  uridine kinase-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WDH0, A0A1P8AWM1

    5. NM_001333735.1 → NP_001323275.1  uridine kinase-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WDH0, A0A1P8AWM1

    6. NM_001333736.1 → NP_001323277.1  uridine kinase-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQ84, Q8VYB2, Q9LG32
      UniProtKB/TrEMBL
      A0A178WDH0

    7. NM_001333737.1 → NP_001323278.1  uridine kinase-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WDD0, A0A1P8AWK0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VYB2.1

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