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    NEK1 NIMA-related serine/threonine kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841893, updated on 15-Feb-2024

    Summary

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    Gene symbol
    NEK1
    Gene description
    NIMA-related serine/threonine kinase 1
    Primary source
    Araport:AT1G54510
    Locus tag
    AT1G54510
    See related
    TAIR:AT1G54510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNEK1; F20D21.32; F20D21_32; NIMA-RELATED KINASE1; NIMA-related serine/threonine kinase 1
    Summary
    Encodes AtNEK1, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
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    Genomic context

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    See NEK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Sequence:
    Chromosome: 1; NC_003070.9 (20358319..20362624, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene exoribonuclease 4 Neighboring gene Rubredoxin-like superfamily protein Neighboring gene myelin-associated oligodendrocyte basic protein Neighboring gene Calcium-binding EF hand family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001198295.1
    NM_001198296.1
    NM_001333653.1
    NM_001333654.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NIMA-related serine/threonine kinase 1
    NP_001185224.1
    • NIMA-related serine/threonine kinase 1 (NEK1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2).
    NP_001319226.1
    • NIMA-related serine/threonine kinase 1 (NEK1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2).
    NP_175853.1
    • NIMA-related serine/threonine kinase 1 (NEK1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2); Has 126786 Blast hits to 124499 proteins in 4540 species: Archae - 112; Bacteria - 14456; Metazoa - 47155; Fungi - 12426; Plants - 31152; Viruses - 487; Other Eukaryotes - 20998 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20358319..20362624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104329.5 → NP_175853.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175853.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    2. NM_001198295.1 → NP_001185224.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185224.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    3. NM_001333653.1 → NP_001319226.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    4. NM_001198296.1 → NP_001185225.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185225.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    5. NM_001333654.1 → NP_001322059.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WLV4, A0A1P8AST4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SLI2.2

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