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    [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838447, updated on 22-Aug-2024

    Summary

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    Primary source
    TAIR:AT1G18660
    Locus tag
    AT1G18660
    See related
    Araport:AT1G18660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6A14.25; F6A14_25
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    19
    Sequence:
    Chromosome: 1; NC_003070.9 (6420856..6425898)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene LONGIFOLIA protein Neighboring gene glycine-rich RNA-binding protein 6 Neighboring gene 3-phosphoserine phosphatase Neighboring gene plasmodesmata callose-binding protein 3 Neighboring gene Protein kinase superfamily protein Neighboring gene HNH endonuclease domain-containing protein Neighboring gene Galactosyl transferase GMA12/MNN10 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING 9 Protein Is a Regulator of Basal Immunity in Arabidopsis thaliana. Wang Y, et al. Mol Plant Microbe Interact, 2019 Jan. PMID 29958083
    2. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
    3. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001332356.1
    NM_101724.3
    NM_179356.3
    NM_179357.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    colocalizes_with plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger (C3HC4-type RING finger) family protein
    NP_001319035.1
    • zinc finger (C3HC4-type RING finger) family protein; FUNCTIONS IN: ATP-dependent peptidase activity, binding, zinc ion binding; INVOLVED IN: proteolysis; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S16, lon N-terminal (InterPro:IPR003111), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Tetratricopeptide-like helical (InterPro:IPR011990), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: ATP-dependent protease La (LON) domain protein (TAIR:AT1G75460.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_564060.1
    • zinc finger (C3HC4-type RING finger) family protein; FUNCTIONS IN: ATP-dependent peptidase activity, binding, zinc ion binding; INVOLVED IN: proteolysis; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S16, lon N-terminal (InterPro:IPR003111), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Tetratricopeptide-like helical (InterPro:IPR011990), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: ATP-dependent protease La (LON) domain protein (TAIR:AT1G75460.1); Has 12320 Blast hits to 11867 proteins in 1696 species: Archae - 10; Bacteria - 754; Metazoa - 7268; Fungi - 935; Plants - 1517; Viruses - 81; Other Eukaryotes - 1755 (source: NCBI BLink).
    NP_849687.1
    • zinc finger (C3HC4-type RING finger) family protein; FUNCTIONS IN: ATP-dependent peptidase activity, binding, zinc ion binding; INVOLVED IN: proteolysis; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S16, lon N-terminal (InterPro:IPR003111), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Tetratricopeptide-like helical (InterPro:IPR011990), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: ATP-dependent protease La (LON) domain protein (TAIR:AT1G75460.1); Has 12320 Blast hits to 11867 proteins in 1696 species: Archae - 10; Bacteria - 754; Metazoa - 7268; Fungi - 935; Plants - 1517; Viruses - 81; Other Eukaryotes - 1755 (source: NCBI BLink).
    NP_849688.1
    • zinc finger (C3HC4-type RING finger) family protein; FUNCTIONS IN: ATP-dependent peptidase activity, binding, zinc ion binding; INVOLVED IN: proteolysis; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S16, lon N-terminal (InterPro:IPR003111), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Tetratricopeptide-like helical (InterPro:IPR011990), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: ATP-dependent protease La (LON) domain protein (TAIR:AT1G75460.1); Has 12352 Blast hits to 11899 proteins in 1704 species: Archae - 10; Bacteria - 756; Metazoa - 7295; Fungi - 938; Plants - 1517; Viruses - 81; Other Eukaryotes - 1755 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6420856..6425898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332356.1 → NP_001319035.1  zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4ICB5, Q8LDH8

    2. NM_179356.3 → NP_849687.1  zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849687.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WKL0, Q8H0X2, Q8LDH8
      Conserved Domains (6) summary
      PLN03088
      Location:42 → 161
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      COG5243
      Location:167 → 254
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      sd00006
      Location:42 → 67
      TPR; TPR repeat [structural motif]
      cd00162
      Location:196 → 233
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      cl19481
      Location:278 → 479
      LON; Found in ATP-dependent protease La (LON)
      cl17238
      Location:193 → 234
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    3. NM_101724.3 → NP_564060.1  zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564060.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WKL0, Q8H0X2, Q8LDH8
      Conserved Domains (6) summary
      PLN03088
      Location:42 → 161
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      COG5243
      Location:167 → 254
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      sd00006
      Location:42 → 67
      TPR; TPR repeat [structural motif]
      cd00162
      Location:196 → 233
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      cl19481
      Location:278 → 479
      LON; Found in ATP-dependent protease La (LON)
      cl17238
      Location:193 → 234
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    4. NM_179357.2 → NP_849688.1  zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849688.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WKL0, Q8H0X2, Q8LDH8
      Conserved Domains (6) summary
      PLN03088
      Location:42 → 161
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      COG5243
      Location:167 → 254
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      sd00006
      Location:42 → 67
      TPR; TPR repeat [structural motif]
      cd00162
      Location:196 → 233
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      cl19481
      Location:278 → 479
      LON; Found in ATP-dependent protease La (LON)
      cl17238
      Location:193 → 234
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein
    Heading Accession and Version

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