Haspin Protein kinase superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: Haspin
Official Full Name: Protein kinase superfamily protein
Primary source: TAIR:AT1G09450
Locus tag: AT1G09450
See related: Araport:AT1G09450
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtHaspin; F14J9.11; F14J9_11; Haspin-related gene
Summary: Encodes a protein kinase that phosphorylates histone H3 at Thr3 and Thr11 and plays a role in mitotic cell division.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

histone phosphorylation by haspin
Title: In vitro phosphorylation of histone H3 at threonine 3 by Arabidopsis haspin is strongly influenced by posttranslational modifications of adjacent amino acids.
AtHaspin phosphorylates histone H3 at threonine 3, and is highly expressed in tissues with a high level of cell proliferation and differentiation.
Title: AtHaspin phosphorylates histone H3 at threonine 3 during mitosis and contributes to embryonic patterning in Arabidopsis.
Haspin kinase is a histone H3 threonine kinase that is involved in cell division.
Title: Identification and characterization of plant Haspin kinase as a histone H3 threonine kinase.

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NM_100816.5

Function	Evidence Code	Pubs
enables histone H3T11 kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables histone H3T3 kinase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in post-translational protein modification	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_172416.2

Protein kinase superfamily protein; FUNCTIONS IN: protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation, N-terminal protein myristoylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719); Has 302 Blast hits to 302 proteins in 127 species: Archae - 0; Bacteria - 0; Metazoa - 120; Fungi - 113; Plants - 37; Viruses - 0; Other Eukaryotes - 32 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain