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    HA3 H[+]-ATPase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835841, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HA3
    Official Full Name
    H[+]-ATPase 3
    Primary source
    TAIR:AT5G57350
    Locus tag
    AT5G57350
    See related
    Araport:AT5G57350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AHA3; ARABIDOPSIS THALIANA ARABIDOPSIS H(+)-ATPASE; ATAHA3; H(+)-ATPase 3; MJB24.16; MJB24_16; P-TYPE H(+)-ATPASE ISOFORM 3
    Summary
    member of Plasma membrane H+-ATPase family
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    Genomic context

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    See HA3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Sequence:
    Chromosome: 5; NC_003076.8 (23230874..23236682, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Galactose mutarotase-like superfamily protein Neighboring gene ras guanine nucleotide exchange factor Q-like protein Neighboring gene uncharacterized protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene U4/U6.U5 small nuclear ribonucleoprotein Neighboring gene Fibronectin type III domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immunocytological localization of an epitope-tagged plasma membrane proton pump (H(+)-ATPase) in phloem companion cells. DeWitt ND, et al. Plant Cell, 1995 Dec. PMID 8718619, Free PMC Article
    2. Functional comparisons between plant plasma membrane H(+)-ATPase isoforms expressed in yeast. Palmgren MG, et al. J Biol Chem, 1994 Jan 28. PMID 8300635
    3. Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Nühse TS, et al. Mol Cell Proteomics, 2003 Nov. PMID 14506206
    4. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    5. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203630.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables P-type proton-exporting transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables P-type proton-exporting transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proton export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    H[+]-ATPase 3
    NP_001190559.1
    • H(+)-ATPase 3 (HA3); FUNCTIONS IN: ATPase activity, hydrogen-exporting ATPase activity, phosphorylative mechanism; INVOLVED IN: cation transport, metabolic process, ATP biosynthetic process; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, plasma-membrane proton-efflux (InterPro:IPR006534), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: H(+)-ATPase 2 (TAIR:AT4G30190.1).
    NP_200545.1
    • H(+)-ATPase 3 (HA3); FUNCTIONS IN: ATPase activity, hydrogen-exporting ATPase activity, phosphorylative mechanism; INVOLVED IN: cation transport, metabolic process, ATP biosynthetic process; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, plasma-membrane proton-efflux (InterPro:IPR006534), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: H(+)-ATPase 2 (TAIR:AT4G30190.1); Has 36687 Blast hits to 32635 proteins in 3162 species: Archae - 691; Bacteria - 23215; Metazoa - 3969; Fungi - 2549; Plants - 1910; Viruses - 3; Other Eukaryotes - 4350 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23230874..23236682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345258.1 → NP_001331203.1  H[+]-ATPase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BD43

    2. NM_125118.3 → NP_200545.1  H[+]-ATPase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200545.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P20431
      UniProtKB/TrEMBL
      A0A178UHY0, A0A5S9YEW2, Q93ZM8
      Conserved Domains (1) summary
      TIGR01647
      Location:33 → 805
      ATPase-IIIA_H; plasma-membrane proton-efflux P-type ATPase

    3. NM_001345259.1 → NP_001331204.1  H[+]-ATPase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P20431
      UniProtKB/TrEMBL
      A0A178UHY0, A0A5S9YEW2, Q93ZM8
      Conserved Domains (1) summary
      TIGR01647
      Location:33 → 805
      ATPase-IIIA_H; plasma-membrane proton-efflux P-type ATPase

    4. NM_001203630.1 → NP_001190559.1  H[+]-ATPase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190559.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P20431
      UniProtKB/TrEMBL
      A0A178UHY0, A0A5S9YEW2, Q93ZM8
      Conserved Domains (1) summary
      TIGR01647
      Location:33 → 805
      ATPase-IIIA_H; plasma-membrane proton-efflux P-type ATPase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20431.2

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