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    GA2OX8 gibberellin 2-oxidase 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827868, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GA2OX8
    Official Full Name
    gibberellin 2-oxidase 8
    Primary source
    TAIR:AT4G21200
    Locus tag
    AT4G21200
    See related
    Araport:AT4G21200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GIBBERELLIN 2-OXIDASE 8; ATGA2OX8; F7J7.140; F7J7_140; gibberellin 2-oxidase 8
    Summary
    Encodes a protein with gibberellin 2-oxidase activity which acts specifically on C-20 gibberellins.
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    Genomic context

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    See GA2OX8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (11302682..11306770)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene DnaJ / Sec63 Brl domains-containing protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene Cytochrome c oxidase biogenesis protein Cmc1-like protein Neighboring gene PPDK regulatory protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A study of gibberellin homeostasis and cryptochrome-mediated blue light inhibition of hypocotyl elongation. Zhao X, et al. Plant Physiol, 2007 Sep. PMID 17644628, Free PMC Article
    2. Overexpression of a novel class of gibberellin 2-oxidases decreases gibberellin levels and creates dwarf plants. Schomburg FM, et al. Plant Cell, 2003 Jan. PMID 12509528, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. scc7-D (suppressors of cry1cry2)is a gain-of-expression allele of the GA2ox8 gene.
      Title: A study of gibberellin homeostasis and cryptochrome-mediated blue light inhibition of hypocotyl elongation.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001160789.1
    NM_001341476.1
    NM_118239.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables C-19 gibberellin 2-beta-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables C-20 gibberellin 2-beta-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gibberellin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gibberellin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    gibberellin 2-oxidase 8
    NP_001154261.1
    • gibberellin 2-oxidase 8 (GA2OX8); FUNCTIONS IN: C-20 gibberellin 2-beta-dioxygenase activity; INVOLVED IN: gibberellin metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, flower; EXPRESSED DURING: petal differentiation and expansion stage; BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 7 (TAIR:AT1G50960.1); Has 2321 Blast hits to 2310 proteins in 244 species: Archae - 0; Bacteria - 75; Metazoa - 4; Fungi - 39; Plants - 2120; Viruses - 0; Other Eukaryotes - 83 (source: NCBI BLink).
    NP_001320018.1
    • gibberellin 2-oxidase 8 (GA2OX8); FUNCTIONS IN: C-20 gibberellin 2-beta-dioxygenase activity; INVOLVED IN: gibberellin metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, flower; EXPRESSED DURING: petal differentiation and expansion stage; BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 7 (TAIR:AT1G50960.1); Has 2972 Blast hits to 2961 proteins in 383 species: Archae - 0; Bacteria - 137; Metazoa - 2; Fungi - 57; Plants - 2676; Viruses - 0; Other Eukaryotes - 100 (source: NCBI BLink).
    NP_193852.2
    • gibberellin 2-oxidase 8 (GA2OX8); CONTAINS InterPro DOMAIN/s: Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 7 (TAIR:AT1G50960.1); Has 8586 Blast hits to 8547 proteins in 1007 species: Archae - 0; Bacteria - 1133; Metazoa - 115; Fungi - 1020; Plants - 4926; Viruses - 0; Other Eukaryotes - 1392 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11302682..11306770
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118239.3 → NP_193852.2  gibberellin 2-oxidase 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193852.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MF87, O49561, Q1PE62
      UniProtKB/TrEMBL
      A0A178UVM9, A0A5S9XUE7, A0A654FRC1
      Conserved Domains (3) summary
      PLN02403
      Location:40 → 333
      PLN02403; aminocyclopropanecarboxylate oxidase
      pfam03171
      Location:186 → 290
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
      pfam14226
      Location:42 → 137
      DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal

    2. NM_001341476.1 → NP_001320018.1  gibberellin 2-oxidase 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UUC9, F4JIN8

    3. NM_001160789.1 → NP_001154261.1  gibberellin 2-oxidase 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154261.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UUC9, F4JIN9
      Conserved Domains (1) summary
      pfam14226
      Location:42 → 105
      DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49561.2

    Gene LinkOut

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