LUT1 Cytochrome P450 superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: LUT1
Official Full Name: Cytochrome P450 superfamily protein
Primary source: TAIR:AT3G53130
Locus tag: AT3G53130
See related: Araport:AT3G53130
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: CYP97C1; CYTOCHROME P450 97C1; LUTEIN DEFICIENT 1
Summary: Lutein-deficient 1 (LUT1) required for lutein biosynthesis, member of the xanthophyll class of carotenoids. Involved in epsilon ring hydroxylation. Maps at 67.3 cM on chromosome 3.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Data shows that LUT1/CYP97C1 protein reveals a major beta-carotene hydroxylase activity in vivo when depleted in its preferred substrate alpha-carotene.
Title: A quadruple mutant of Arabidopsis reveals a β-carotene hydroxylation activity for LUT1/CYP97C1 and a regulatory role of xanthophylls on determination of the PSI/PSII ratio.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_115173.3

Function	Evidence Code	Pubs
enables carotene epsilon hydroxylase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carotenoid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast	TAS Traceable Author Statement more info	PubMed
located_in chloroplast envelope	HDA more info	PubMed

NP_190881.2

LUTEIN DEFICIENT 1 (LUT1); FUNCTIONS IN: epsilon hydroxylase activity, oxygen binding; INVOLVED IN: carotenoid biosynthetic process; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 97, subfamily A, polypeptide 3 (TAIR:AT1G31800.1); Has 31038 Blast hits to 30928 proteins in 1581 species: Archae - 62; Bacteria - 3557; Metazoa - 11361; Fungi - 6359; Plants - 8451; Viruses - 3; Other Eukaryotes - 1245 (source: NCBI BLink).