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    SYP122 syntaxin of plants 122 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824405, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SYP122
    Official Full Name
    syntaxin of plants 122
    Primary source
    TAIR:AT3G52400
    Locus tag
    AT3G52400
    See related
    Araport:AT3G52400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSYP122; syntaxin of plants 122
    Summary
    syntaxin protein, involved in the negative regulation of defense pathways such as programmed cell death, salicylic acid signalling pathway, jasmonic acid signalling pathway
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    Genomic context

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    See SYP122 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (19425632..19427230, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene FASCICLIN-like arabinogalactan protein 15 precursor Neighboring gene chloroplast RNA-binding protein 33 Neighboring gene TatD related DNase Neighboring gene pseudo Neighboring gene outer envelope membrane protein 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SNAREs SYP121 and SYP122 Mediate the Secretion of Distinct Cargo Subsets. Waghmare S, et al. Plant Physiol, 2018 Dec. PMID 30348815, Free PMC Article
    2. A SNARE-protein has opposing functions in penetration resistance and defence signalling pathways. Zhang Z, et al. Plant J, 2007 Jan. PMID 17241452
    3. The PEN1 syntaxin defines a novel cellular compartment upon fungal attack and is required for the timely assembly of papillae. Assaad FF, et al. Mol Biol Cell, 2004 Nov. PMID 15342780, Free PMC Article
    4. The carbon/nitrogen regulator ARABIDOPSIS TOXICOS EN LEVADURA31 controls papilla formation in response to powdery mildew fungi penetration by interacting with SYNTAXIN OF PLANTS121 in Arabidopsis. Maekawa S, et al. Plant Physiol, 2014 Feb. PMID 24394775, Free PMC Article
    5. Selective targeting of plasma membrane and tonoplast traffic by inhibitory (dominant-negative) SNARE fragments. Tyrrell M, et al. Plant J, 2007 Sep. PMID 17662029

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SYP121 and SYP122 are associated with different subsets of cargo proteins that are targeted for secretion at the plasma membrane.
      Title: SNAREs SYP121 and SYP122 Mediate the Secretion of Distinct Cargo Subsets.
    2. The domain of SEC11 that bound the SYP121 N terminus was itself able to block secretory traffic in the wild type and syp122 but not in syp121 mutant Arabidopsis.
      Title: Binding of SEC11 indicates its role in SNARE recycling after vesicle fusion and identifies two pathways for vesicular traffic to the plasma membrane.
    3. SYP122 may have a general function in secretion and a role in cell wall deposition, while its homolog PEN1 appears to have a basal function in secretion and a specialized defense-related function
      Title: The PEN1 syntaxin defines a novel cellular compartment upon fungal attack and is required for the timely assembly of papillae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_115100.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables SNAP receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SNAP receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to fungus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular protein transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within jasmonic acid mediated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within membrane fusion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of cellular defense response IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of programmed cell death IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of plant-type hypersensitive response IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within salicylic acid mediated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    syntaxin of plants 122
    NP_190808.1
    • syntaxin of plants 122 (SYP122); FUNCTIONS IN: SNAP receptor activity; INVOLVED IN: in 9 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Target SNARE coiled-coil domain (InterPro:IPR000727), t-SNARE (InterPro:IPR010989), Syntaxin/epimorphin, conserved site (InterPro:IPR006012), Syntaxin, N-terminal (InterPro:IPR006011); BEST Arabidopsis thaliana protein match is: syntaxin of plants 121 (TAIR:AT3G11820.2); Has 2448 Blast hits to 2448 proteins in 275 species: Archae - 5; Bacteria - 34; Metazoa - 1056; Fungi - 527; Plants - 461; Viruses - 0; Other Eukaryotes - 365 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19425632..19427230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115100.3 → NP_190808.1  syntaxin of plants 122 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190808.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SUJ2, Q9SVC2
      UniProtKB/TrEMBL
      A0A178VEE7, A0A5S9XKX9
      Conserved Domains (2) summary
      pfam00804
      Location:43 → 248
      Syntaxin
      cl22856
      Location:216 → 282
      SNARE; SNARE motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SVC2.1

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