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    UKL5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822365, updated on 22-Aug-2024

    Summary

    Official Symbol
    UKL5
    Primary source
    Araport:AT3G27440
    Locus tag
    AT3G27440
    See related
    TAIR:AT3G27440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    uridine kinase-like 5
    Summary
    One of the homologous genes predicted to encode proteins with UPRT domains (Uracil phosphoribosyltransferase). Five of these genes (At5g40870, At3g27190, At1g55810, At4g26510 and At3g27440) show a high level of identity, and are annotated as also containing a N-terminal uracil kinase (UK) domain. These genes are referred to as UKL1 (UK-like 1), UKL2, UKL3, UKL4 and UKL5, respectively.
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    Genomic context

    See UKL5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (10155438..10158215)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene bromodomain testis-specific protein Neighboring gene ECA1-like gametogenesis related family protein Neighboring gene N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein Neighboring gene miscRNA Neighboring gene SGF29 tudor-like domain-containing protein

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables uracil phosphoribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables uridine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in CTP salvage IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in UMP salvage IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    uridine kinase-like 5
    NP_189380.1
    • uridine kinase-like 5 (UKL5); FUNCTIONS IN: uracil phosphoribosyltransferase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 13214 Blast hits to 13202 proteins in 2627 species: Archae - 217; Bacteria - 10041; Metazoa - 552; Fungi - 516; Plants - 596; Viruses - 2; Other Eukaryotes - 1290 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10155438..10158215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338873.1NP_001326122.1  uridine kinase-like 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VGZ4, A0A1I9LNB3
    2. NM_113659.2NP_189380.1  uridine kinase-like 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189380.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LTY6
      UniProtKB/TrEMBL
      A0A178VGZ4, A0A5S9XGX8
      Conserved Domains (2) summary
      cd02023
      Location:31228
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:246447
      UPRTase; Uracil phosphoribosyltransferase
    3. NM_001338874.1NP_001326121.1  uridine kinase-like 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VGZ4, A0A1I9LNB2