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    SIEL ARM repeat superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820027, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SIEL
    Official Full Name
    ARM repeat superfamily protein
    Primary source
    TAIR:AT3G08800
    Locus tag
    AT3G08800
    See related
    Araport:AT3G08800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SHORT-ROOT interacting embryonic lethal
    Summary
    Encodes a nuclear and endosome localized protein with ARM and HEAT domains that interacts with SHR and other non-cell-autonomous proteins and may be involved in their intercellular movement. Hypomorphic mutant phenotypes suggest involvement of the protein in root patterning.
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    Genomic context

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    See SIEL in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (2671052..2675333)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene lipid transfer protein 6 Neighboring gene BRISC complex subunit Abro1-like protein Neighboring gene ENTH/VHS/GAT family protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An essential protein that interacts with endosomes and promotes movement of the SHORT-ROOT transcription factor. Koizumi K, et al. Curr Biol, 2011 Sep 27. PMID 21924907
    2. The movement of the non-cell-autonomous transcription factor, SHORT-ROOT relies on the endomembrane system. Wu S, et al. Plant J, 2014 Nov. PMID 25124761
    3. snRNA 3' End Processing by a CPSF73-Containing Complex Essential for Development in Arabidopsis. Liu Y, et al. PLoS Biol, 2016 Oct. PMID 27780203, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SHR can move from multiple different cell types in the root. Analysis of subcellular localization indicates that in the cytoplasm of root or leaf cells, SHR localizes to endosomes in a SIEL-dependent manner.
      Title: The movement of the non-cell-autonomous transcription factor, SHORT-ROOT relies on the endomembrane system.
    2. SIEL localizes to the nucleus and cytoplasm of root cells where it is associated with endosomes.
      Title: An essential protein that interacts with endosomes and promotes movement of the SHORT-ROOT transcription factor.
    Submit: New GeneRIF Correction

    General gene information

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    NM_111714.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within intercellular transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root radial pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within snRNA 3'-end processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ARM repeat superfamily protein
    NP_187492.2
    • ARM repeat superfamily protein; FUNCTIONS IN: binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); Has 149 Blast hits to 148 proteins in 72 species: Archae - 0; Bacteria - 6; Metazoa - 108; Fungi - 3; Plants - 22; Viruses - 0; Other Eukaryotes - 10 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2671052..2675333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337771.1 → NP_001326641.1  ARM repeat superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LPW8

    2. NM_001337772.1 → NP_001326642.1  ARM repeat superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LPW8

    3. NM_111714.4 → NP_187492.2  ARM repeat superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187492.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZA0, Q9C9Y0
      UniProtKB/TrEMBL
      A0A178V721
      Conserved Domains (2) summary
      COG1413
      Location:206 → 453
      HEAT; HEAT repeat [General function prediction only]
      sd00044
      Location:349 → 375
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VZA0.1

    Gene LinkOut

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