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    qrsl1 QRSL1, glutaminyl-tRNA amidotransferase subunit A [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 780239, updated on 4-Nov-2024

    Summary

    Official Symbol
    qrsl1provided by Xenbase
    Official Full Name
    QRSL1, glutaminyl-tRNA amidotransferase subunit Aprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-5787967
    See related
    Ensembl:ENSXETG00000027717 AllianceGenome:Xenbase:XB-GENE-5787967
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to act upstream of or within translation. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 40. Orthologous to human QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See qrsl1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (79111299..79132311, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (76140093..76161097, complement)

    Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene mitochondrial transcription rescue factor 1 Neighboring gene uncharacterized LOC100490489 Neighboring gene reticulon 4 interacting protein 1 Neighboring gene crystallin beta-gamma domain containing 1

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • MGC146451

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in glutaminyl-tRNAGln biosynthesis via transamidation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within glutaminyl-tRNAGln biosynthesis via transamidation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mitochondrial translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of glutamyl-tRNA(Gln) amidotransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of glutamyl-tRNA(Gln) amidotransferase complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
    Names
    glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
    glutamyl-tRNA(Gln) amidotransferase subunit A homolog
    NP_001072779.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079311.1NP_001072779.1  glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

      See identical proteins and their annotated locations for NP_001072779.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118816
      UniProtKB/Swiss-Prot
      Q0VFI5
      UniProtKB/TrEMBL
      A0A6I8QT22
      Related
      ENSXETP00000072343.2, ENSXETT00000095112.2
      Conserved Domains (1) summary
      PRK00012
      Location:13494
      gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      79111299..79132311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)