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    isoc1 isochorismatase domain containing 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 780052, updated on 4-Nov-2024

    Summary

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    Official Symbol
    isoc1provided by Xenbase
    Official Full Name
    isochorismatase domain containing 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-491284
    See related
    Ensembl:ENSXETG00000008281 AllianceGenome:Xenbase:XB-GENE-491284
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    cgi-111
    Summary
    Predicted to be active in cytoplasm. Orthologous to human ISOC1 (isochorismatase domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See isoc1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (167448741..167459447, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (158886625..158897261, complement)

    Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene membrane integral NOTCH2 associated receptor 2 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 19 Neighboring gene uncharacterized LOC101733588 Neighboring gene small nucleolar RNA SNORD34 Neighboring gene solute carrier family 27 member 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC146040

    Gene Ontology Provided by Xenbase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    isochorismatase domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079129.1 → NP_001072597.1  isochorismatase domain-containing protein 1

      See identical proteins and their annotated locations for NP_001072597.1

      Status: PROVISIONAL

      Source sequence(s)
      BC122966
      UniProtKB/Swiss-Prot
      Q0IHU5
      UniProtKB/TrEMBL
      A0A5S6LA88
      Related
      ENSXETP00000018162.5, ENSXETT00000018162.5
      Conserved Domains (1) summary
      cd01012
      Location:126 → 280
      YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      167448741..167459447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012965593.3 → XP_012821047.2  isochorismatase domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A803J4B6, A0A803J6K5
      Related
      ENSXETP00000102669.1, ENSXETT00000120190.1
      Conserved Domains (1) summary
      cd01012
      Location:135 → 289
      YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...

    2. XM_012965599.3 → XP_012821053.2  isochorismatase domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A803J6K5, A0A803JUD3
      Related
      ENSXETP00000111618.1, ENSXETT00000121880.1
      Conserved Domains (1) summary
      cd01012
      Location:134 → 288
      YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...

    3. XM_018094550.2 → XP_017950039.2  isochorismatase domain-containing protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q0IHU5
      UniProtKB/TrEMBL
      A0A5S6LA88
      Conserved Domains (1) summary
      cd01012
      Location:126 → 280
      YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0IHU5.1 GenPept UniProtKB/Swiss-Prot:Q0IHU5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.