wdr91 WD repeat domain 91 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: wdr91provided by Xenbase
Official Full Name: WD repeat domain 91provided by Xenbase
Primary source: Xenbase:XB-GENE-969792
See related: Ensembl:ENSXETG00000020237 AllianceGenome:Xenbase:XB-GENE-969792
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable phosphatidylinositol 3-kinase inhibitor activity. Predicted to be involved in early endosome to late endosome transport. Predicted to act upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in cytosol and endosome membrane. Predicted to be active in early endosome membrane and late endosome membrane. Orthologous to human WDR91 (WD repeat domain 91). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	3	NC_030679.2 (6785767..6815104)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	Unplaced Scaffold	NW_016683467.1 (266969..301185, complement)

Chromosome 3 - NC_030679.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables phosphatidylinositol 3-kinase inhibitor activity	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol 3-kinase inhibitor activity	ISS Inferred from Sequence or Structural Similarity more info
enables phosphatidylinositol 3-kinase regulator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in early endosome to late endosome transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within early endosome to late endosome transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within early endosome to late endosome transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
is_active_in early endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
located_in early endosome membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in endosome membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in late endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
located_in late endosome membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WD repeat-containing protein 91

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079111.1 → NP_001072579.1 WD repeat-containing protein 91

See identical proteins and their annotated locations for NP_001072579.1

Status: PROVISIONAL

Source sequence(s)

BC122936

UniProtKB/Swiss-Prot

Q05B30

UniProtKB/TrEMBL

A0A6I8RSE2, A0A8J1JBA0

Related

ENSXETP00000057530.4, ENSXETT00000057530.4

Conserved Domains (2) summary

sd00039
Location:416 → 452

7WD40; WD40 repeat [structural motif]

cl29593
Location:407 → 743

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

6785767..6815104

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_031898071.1 → XP_031753931.1 WD repeat-containing protein 91 isoform X1

UniProtKB/Swiss-Prot

Q05B30

UniProtKB/TrEMBL

A0A6I8RSE2, A0A8J1JBA0

Conserved Domains (2) summary

sd00039
Location:416 → 452

7WD40; WD40 repeat [structural motif]

cl29593
Location:407 → 743

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...