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    ecsit ECSIT signalling integrator [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 779865, updated on 25-Apr-2024

    Summary

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    Official Symbol
    ecsitprovided by Xenbase
    Official Full Name
    ECSIT signalling integratorprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-853811
    See related
    Ensembl:ENSXETG00000016738
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    sitpec
    Orthologs
    human mouse all
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    Genomic context

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    See ecsit in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (139300497..139310446, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (128433993..128441421, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene ELAV like neuron-specific RNA binding protein 3 Neighboring gene zinc finger protein 653 Neighboring gene TLC domain containing 4, gene 2 Neighboring gene calponin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC147313

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    involved_in cell surface receptor protein serine/threonine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of oxidoreductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within regulation of protein complex stability ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
    Names
    ECSIT homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078943.1 → NP_001072411.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001072411.1

      Status: PROVISIONAL

      Source sequence(s)
      BC121633
      UniProtKB/Swiss-Prot
      Q0V9C9
      UniProtKB/TrEMBL
      A0A803K392
      Related
      ENSXETP00000114799.1, ENSXETT00000122957.1
      Conserved Domains (3) summary
      sd00004
      Location:78 → 106
      PPR; PPR repeat [structural motif]
      pfam06239
      Location:41 → 252
      ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
      pfam14784
      Location:255 → 377
      ECSIT_C; C-terminal domain of the ECSIT protein

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      139300497..139310446 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012953176.3 → XP_012808630.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_012808630.1

      UniProtKB/Swiss-Prot
      Q0V9C9
      UniProtKB/TrEMBL
      A0A803K392
      Conserved Domains (3) summary
      sd00004
      Location:78 → 106
      PPR; PPR repeat [structural motif]
      pfam06239
      Location:41 → 252
      ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
      pfam14784
      Location:255 → 377
      ECSIT_C; C-terminal domain of the ECSIT protein

    2. XM_031898055.1 → XP_031753915.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A803K392, A0A8J1JA68
      Conserved Domains (3) summary
      sd00004
      Location:78 → 106
      PPR; PPR repeat [structural motif]
      pfam06239
      Location:43 → 252
      ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
      pfam14784
      Location:255 → 348
      ECSIT_C; C-terminal domain of the ECSIT protein

    3. XM_031898056.1 → XP_031753916.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A803K392, A0A8J1JB83
      Conserved Domains (3) summary
      sd00004
      Location:78 → 106
      PPR; PPR repeat [structural motif]
      pfam06239
      Location:43 → 252
      ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
      pfam14784
      Location:255 → 348
      ECSIT_C; C-terminal domain of the ECSIT protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0V9C9.1 GenPept UniProtKB/Swiss-Prot:Q0V9C9

    Gene LinkOut

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