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    Mettl27 methyltransferase like 27 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688407, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Mettl27provided by RGD
    Official Full Name
    methyltransferase like 27provided by RGD
    Primary source
    RGD:1588881
    See related
    EnsemblRapid:ENSRNOG00000046700 AllianceGenome:RGD:1588881
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Wbscr27
    Summary
    Orthologous to human METTL27 (methyltransferase like 27). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in Kidney (RPKM 74.5), Heart (RPKM 50.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mettl27 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (27394067..27403220, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (21757545..21766698, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (24767351..24775891, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene actin related protein 2/3 complex, subunit 5-like, pseudogene 3 Neighboring gene claudin 4 Neighboring gene claudin-4-like Neighboring gene uncharacterized LOC120095920 Neighboring gene transmembrane protein 270

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    methyltransferase-like protein 27
    Names
    Williams Beuren syndrome chromosome region 27
    Williams-Beuren syndrome chromosomal region 27 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109499.3 → NP_001102969.1  methyltransferase-like protein 27

      See identical proteins and their annotated locations for NP_001102969.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A8I6AP98, A6J0G7, D4AED6
      Conserved Domains (1) summary
      pfam13649
      Location:71 → 162
      Methyltransf_25; Methyltransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      27394067..27403220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089764.1 → XP_038945692.1  methyltransferase-like protein 27 isoform X2

      UniProtKB/TrEMBL
      D4AED6
      Conserved Domains (2) summary
      COG4976
      Location:30 → 115
      COG4976; Predicted methyltransferase, contains TPR repeat [General function prediction only]
      pfam13649
      Location:71 → 109
      Methyltransf_25; Methyltransferase domain

    2. XM_039089763.1 → XP_038945691.1  methyltransferase-like protein 27 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZPD6, D4AED6
      Related
      ENSRNOP00000065369.3, ENSRNOT00000074851.3
      Conserved Domains (1) summary
      pfam13649
      Location:71 → 162
      Methyltransf_25; Methyltransferase domain
    Nucleotide Protein Strain
    Heading Accession and Version

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