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    mettl27 methyltransferase like 27 [ Danio rerio (zebrafish) ]

    Gene ID: 678636, updated on 28-Oct-2024

    Summary

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    Official Symbol
    mettl27provided by ZNC
    Official Full Name
    methyltransferase like 27provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060421-5918
    See related
    Ensembl:ENSDARG00000069507 AllianceGenome:ZFIN:ZDB-GENE-060421-5918
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wbscr27; im:7139431; wu:fe50c11; zgc:136279
    Summary
    Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Orthologous to human METTL27 (methyltransferase like 27). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mettl27 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (25795965..25801956, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (25759275..25765351, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene claudin 28 Neighboring gene claudin 30 Neighboring gene NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor b Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene calneuron 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The lasting after-effects of an ancient polyploidy on the genomes of teleosts. Conant GC. PLoS One, 2020. PMID 32298330, Free PMC Article
    2. Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Gao S, et al. Biochim Biophys Acta Gen Subj, 2017 Mar. PMID 27773705
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC136279

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    methyltransferase-like protein 27
    Names
    Williams Beuren syndrome chromosome region 27

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040381.1 → NP_001035471.1  methyltransferase-like protein 27

      See identical proteins and their annotated locations for NP_001035471.1

      Status: PROVISIONAL

      Source sequence(s)
      BC115068
      UniProtKB/TrEMBL
      Q1RMA0
      Related
      ENSDARP00000091993.3, ENSDART00000101219.5
      Conserved Domains (1) summary
      pfam08241
      Location:71 → 165
      Methyltransf_11; Methyltransferase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      25795965..25801956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005161203.5 → XP_005161260.1  methyltransferase-like protein 27 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B874
      Conserved Domains (1) summary
      pfam08241
      Location:71 → 165
      Methyltransf_11; Methyltransferase domain
    Nucleotide Protein Strain
    Heading Accession and Version

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